Biomedical subjects
Publications and source records attributed to A Tozzi.
Vascular injuries in the arthroscopic meniscectomy of the knee are uncommon. A case of pseudoaneurysm of the descending genicular artery in a 39-year-old man, after medial arthroscopic meniscectomy, is reported. The pseudoaneurysm was simple to diagnose with computed tomographic scan and angiography, and treatment was successful surgical resection.
Twenty-six children (mean age: 16.3 months) with vomiting and/or respiratory symptoms and 28 children (mean age 10.5 months) with vomiting and/or regurgitation underwent dual-site 24-hour oesophageal pH recording. Thirty-nine children had gastro-oesophageal reflux and in all of them, irrespective of respiratory symptoms, distal oesophageal acid exposure was significantly (p < 0.01) longer than proximal exposure. Furthermore, data from the proximal pH electrode were not significantly different between children with and without respiratory symptoms for any of the variables studied. In conclusion, no single features of reflux pattern, as determined by 24-hours pH-metry, account for respiratory symptoms in children with documented gastro-oesophageal reflux.
A case of cystic degeneration of the popliteal artery in a 58-year-old male is reported. Symptoms consisted of a claudication of abrupt onset and the correct diagnostic clue was initially given by magnetic resonance of the knee and confirmed by angiography. Treatment consisted of surgical removal of the cyst and saphenous vein angioplasty of the popliteal artery, with good anatomic and functional result at one year follow-up. Diagnostic tools and treatment of the condition are briefly discussed.
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The paper describes the obstetric management of an unique case of twin, bicorial, biamniotic pregnancy in which the second twin born 36 days after the first. Both twins are living today.
A simple, inexpensive and novel method is proposed to acquire information on the motion characteristics of a patient during ambulation, by assuming the earth's magnetic field as reference.
At certain doses metoclopramide (MT), sulpiride and bromopride produce anti-cholinesterase effects as shown by studies on the serum and erythrocyte cholinesterases of the rabbit and the dog, and by those on the hypotensive effect of ACh incubated with rabbit serum in the presence or absence of MT. The anti-cholinesterase effect of MT was more intensive than that of sulpiride, bromopride, procainamide or procaine, but less pronounced than that of prostigmine.
Following the casual observation of an unusual possibility of achieving telepathic communication during a hypno-therapeutic relationship, an examination was made of the real existence of this phenomenon and its extent through a systematic projective research. The positive results noted in 16 subjects, while offering little possibility of expressing a final and certain judgement on the point, are highly significant, and suggest that the therapist should establish a true and intense relationship with the patient before him. It is only by satisfying these requirements that the transference relationship will allow the achievement of the results expected, and remain a supremely rewarding experience for the partners.
Organic pathologies with psychoaffective aetiology are numerous, and in all diseases, mental and rational elements are concomitant with the organic situation. Aware of the psycho-dynamic mechanisms he sets in motion by his actions and appreciating those underlying the symptomatology he has to deal with, the hypnologist transcends the overspecialisation of medical science to restore the patient's psycho-physical unitary reality. This explains both the possibilities of hypnositherapy in general medicine and its impassable limits. The hypnositherapy that the general practitioner can (and most implement must be perfected by a qualified psychotherapeutist when symptomatology cannot be eradicated without tackling the aetiological factor with a serious analysis of the profound. Hypnosis is, therefore, an extra therapeutic possibility for the physician and this is why it can only be used with science, awareness and on the basis of ethics.
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BACKGROUND: The diagnosis of oesophagitis is mainly based on histology, but interpretation of endoscopic biopsies is often difficult. We performed immunohistochemical studies on oesophageal biopsies to see if better characterization of the inflammatory cell infiltrate would improve the accuracy of the histologic diagnosis of gastro-oesophageal reflux disease. METHODS: The study groups consisted of 40 consecutive children (mean age +/- SD: 79.6 +/- 5l.9 months; 20 boys) with gastro-oesophageal reflux disease and 7 symptomatic children (mean age +/- SD: 52.6 +/- 37.0 months; 3 boys) without gastro-oesophageal reflux disease. All patients underwent upper gastrointestinal endoscopy with oesophageal biopsies. The diagnosis of gastro-oesophageal reflux disease was established by conventional endoscopic and histologic criteria. In each mucosal biopsy specimen, the number of intraepithelial CD3+, CD25+ (IL2 receptor+), ICAM+, HLA-DR+ and mucosal mast cells were determined. RESULTS: Conventional histology was in close agreement with endoscopic findings (p<0.001) and reflected the clinical score even more than endoscopic findings. Conventional histology significantly correlated with each inflammatory immunohistochemical marker (<0.05 for each), but the markers were not predictive of symptom severity. Immunohistochemical markers were always abnormal in the gastro-oesophageal reflux disease patients, even in the mildest cases of oesophagitis. CONCLUSIONS: Although there is a good correlation between symptoms and histology, in a subset of patients, immunohistochemical studies appear useful in supporting the histological diagnosis of gastro-oesophageal reflux disease.
A 69-year-old man living in Florence reported fever and acute lumbar pain one month after transurethral resection of a superficial transitional cell carcinoma of the bladder. The radionuclide bone scan suggested metastatic lesions of the L3-L4 vertebrae. However cobalt treatment was ineffective. A bone biopsy of L4 showed an inflammatory pattern and antibiotic therapy was started which did not produce any clinical improvement. Six months after the onset of the back pain brucellar spondylitis was serologically diagnosed and treatment with doxycycline and streptomycin produced a significant clinical and radiological improvement. After 2 months the patient's wife presented with fever and lumbar pain, and brucellar spondylitis was diagnosed as well. An extensive epidemiological examination revealed that 8 months earlier the family had eaten unpasteurized goat cheese and serological examination of the entire family showed that 3 out of 4 members had significant titres of brucellar antibodies. Finally it was discovered that 4 months after consuming the cheese the third infected subject experienced an episode of epidydimoorchitis for which no diagnosis and effective treatment was found. This family cluster of brucellar infection indicates that a high degree of suspicion in the diagnosis of brucellosis is necessary even in non-endemic areas, to reduce the delay in the diagnosis and treatment of the disease and to prevent the occurrence of complications that may prove difficult to treat.