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Biomedical subjects

A Tugayé

Publications and source records attributed to A Tugayé.

6 recordsLinked to original sources
PubMed1991

[A new contribution of Doppler echography of renal arteries: follow-up studies of angioplasties. A retrospective study of 50 cases].

OBJECTIVE: analysis of Doppler Duplex (DD) contribution to renal artery percutaneous angioplasty (ATL) follow-up. METHOD: between 1983 and 1989, SO ATL were performed in 47 subjects with renovascular hypertension. Their average age was 50 +/- 12 years. The lesions were fibromuscular dysplasia (n = 20) and atherosclerosis (n = 27). The DD was performed simultaneously with arteriography (A degrees) (considered the gold standard), when the stenosis was discovered (n = 32), before (n = 32) and after (n = 39) ATL, and during the follow-up between the 6th and 12th month (n = 38). RESULTS: during the initial exploration, the concordance between DD and A degrees is 78% and the sensitivity of DD for the diagnosis of stenosis is 90%. ATL was performed once on the basis of DD alone, that showed a tight and significant stenosis with dysplasia, when A degrees failed to detect it. ATL confirmed the lesion and was successful, and hypertension cured. The concordance DD-A degrees before and after ATL is respectively 88% and 77%. At the late control, the concordance is 92%, the sensitivity 73% and the specificity 85% for all stenosis. While maintaining a good specificity, DD recognized the 3 tight found by the A degrees control. The complications encountered during ATL were diagnosed by DD most of the time: all the local complications at the site of entry (n = 5), all the dissections with obliteration (n = 2) and 5 of the 8 dissections without obliteration of the renal artery. CONCLUSION: the detection and the lesional assessment of post-ATL complications are facilitated by DD. The good sensitivity of DD combined with satisfactory specificity will allow the reduction of angiographic surveillance by taking advantage of a non-invasive method.

Adult↗
PubMed1990

[Creatinine levels in polycystic kidney disease complicated by arterial hypertension. Role of blood pressure control].

As hypertension often precedes renal failure in polycystic kidney disease, it has been suggested that efficient blood pressure control could slow down the progress of the disease. To test this hypothesis, we made a retrospective study of 32 hypertensive patients with familial polycystic kidney disease who had been followed up for an average period of 75 months (range: 20 to 168 months). We examined the relations between creatinine levels or the slope for their increase with time on the one hand, and the mean blood pressure measurements recorded during the surveillance period on the other hand. For the group of 32 patients as a whole, there was no significant correlation between creatinine levels or their variations and blood pressure or its variations. The 13 patients whose creatinine levels rose by more than 50 p. 100 did not differ from the 19 others as regards age, known duration of hypertension, initial or final blood pressure or the number or nature of the antihypertensive drugs they received. This preliminary investigation does not rule out the existence of a link between blood pressure control and the maintenance of renal function during polycystic kidney disease complicated by hypertension, but it does suggest that any such link is tenuous.

Adult↗
PubMed1981

[Screening for phaeochromocytoma : in which hypertensive patients? A semiological study of 2585 patients, including 11 with phaeochromocytoma (author's transl)].

In an attempt to find out whether phaeochromocytoma could be screened by questioning, the authors have recorded in a population of 2585 hypertensive patients the symptoms known to be most frequently associated with the tumour, i.e. headaches, palpitations and sweating attacks. Since 72.4% of the entire population reported one or another of these complaints, no single symptom could be taken as suggestive of phaeochromocytoma. However, only 6.5% of the patients reported all three symptoms and could therefore be considered as forming a subgroup likely to have the tumour. Patients in this subgroup differed from the others in the predominance of females (p less than 0.01), the higher frequency of anxiety (p less than 0.01) and above all, the higher incidence of phaeochromocytoma (5.9% as against 0.04%; p less than 0.01). The symptomatic triad (headaches, palpitations, sweating attacks) has a specificity of 93.8%, a sensitivity of 90.9% and an exclusion value of 99.9% for the diagnosis of phaeochromocytoma. Its presence in hypertensive patients justifies systematic assays of blood or urinary catecholamines. In its absence, the probability of phaeochromocytoma is inferior to 1 in 1 000.

Adrenal Gland Neoplasms↗