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Biomedical subjects

A Tukić

Publications and source records attributed to A Tukić.

6 recordsLinked to original sources

Work performance evaluation in patients suffering from hypertension.

In 41 patients suffering from hypertension blood pressure values obtained in routine examinations in an outpatient clinic were analysed by correlating the highest values of blood pressure measured using the 24-hour monitoring model developed by Holter and those obtained in exertion tests developed by Bruce. The correlation coefficients indicated poor correlation. The results proved the author's hypothesis that it was not possible to predict blood pressure development in 24-hour monitoring based on values of blood pressures obtained in routine outpatient practice only nor could these values be used for the assessment of work performance. It can be concluded that individual functional testing of patients suffering from hypertension is the best method for assessing their work performance.

Blood Pressure Monitoring, Ambulatory↗

Perfect-mixer retention function by analytical deconvolution of tracer histograms: application to evaluation of left-ventricular contractility and competence.

The analytical solution for the perfect-mixer retention function, r(t), was developed from tracer histograms sampled at the system input, i(t), and its output, y(t), linked by the convolution integral y = i * r. Theories were developed for both continuous-output mixer and pulsatile, discrete mixer. The latter method was applied in first-pass radioangiography (FPRA) to calculate the forward ejection fraction of the left ventricle (LVFEF). Curves generated over the lungs and the ventricle provided system input and output respectively. LVFEF correlated strongly with the reference values obtained with simultaneously acquired gated FPRA(LVGEF) in 32 non-regurgitant patients: LVGEF = 0.90LVFEF + 5.93, r = 0.96, SEE = 3.98, p less than 0.001. In 14 patients with left-side valvular incompetence LVFEF values (0.41 +/- 0.13) were consistently lower than the corresponding LVGEF values (0.63 +/- 0.11). The method is free from instability inherent in numerical deconvolution. Applied in FPRA it yielded accurate estimates of LV contractility and competence. The continuous-mixer theory may apply to arbitrary compartmental models studied via tracer kinetics.

Adolescent↗