Biomedical subjects

A Uzel

Publications and source records attributed to A Uzel.

5 recordsLinked to original sources

PubMed2005

Antibiotics prophylaxis in laparoscopy.

OBJECTIVE: This study was to determine which prophylactic antibiotic regimen is most effective in reducing the incidence of infectious morbidity in women undergoing laparoscopy. DESIGN: Randomized, nonblinded comparative study of a single preoperative dose of first generation cephalosporins vs. the control group which did not receive the antibiotic. METHODS: The operations were performed using standard technique. Women (n = 450) with indication for laparoscopy were randomly allocated to two groups. Group 1 (n = 200) received the single dose in first generation cephalosporins and group 2 (n = 250) did not receive it. Both groups were followed up during 7 days for detection of signs of wound infection, idiopathic fever, peritonitis and urinary tract infection, and respiratory tract. Prevalence of postoperative infection, mean hospital stay. RESULTS: Women completing the study (n = 450) were distributed into group 1 (n = 200) and group 2 (n = 250). No significant difference was found either in the prevalence of postoperative infection or in the mean hospital stay. No death occurred. Each patient was assessed daily until discharge to evidence wound infection, idiopathic fever, peritonitis and urinary tract infection, and respiratory tract. Hospital stay did not differ significantly between groups (p>0.005). CONCLUSION: In our setting, the administration of a single dose of 2 g of first generation cephalosporins before laparoscopy for prevention of infection is clinically equivalent to control group. Single dose of 2 g of first generation cephalosporins appears to offer no added benefit over control group.

Adult↗

PubMed2004

Chemical composition and antimicrobial activity of the essential oils of Anthemis xylopoda O. Schwarz from Turkey.

The chemical composition and the antimicrobial activity of the essential oils isolated from the leaves (LEO) and flowers (FEO) of Anthemis xylopoda, an endemic taxon of Turkey, were investigated. Borneol was the major constituent of both the oils studied (30.15 and 31.85%, respectively). The antimicrobial activities of both oils were separately evaluated against 13 microorganisms. The disc diffusion method was used for the antimicrobial activity test. Results showed that both oils of Anthemis xylopoda exhibited a significant antimicrobial activity.

Anthemis↗

PubMed2004

Transmission of Streptococcus mutans in a group of Turkish families.

BACKGROUND/AIMS: To investigate the transmission of Streptococcus mutans in a group of Turkish families using AP-polymerase chain reaction (PCR) detection. METHODS: Eight mothers who had high S. mutans levels in unstimulated saliva and 8 children aged between 2 and 3 years participated in the study. Plaque samples from each child were collected with the tips of sterile toothpicks for S. mutans counts. Although not part of the original study design, S. mutans samples were also obtained from the unstimulated saliva of the three fathers who shared the same households. Three typical isolates of S. mutans were isolated from TYCSB agar of each subject and identified by sugar fermentation tests. S. mutans ATCC 10449 was used as the reference strain. AP-PCR was conducted with OPA-05 primer. RESULTS: All of the mothers and fathers shared the similar genotypes within their children. The fathers also harbored similar genotypes to their spouses. CONCLUSION: The mothers or the fathers could be the source for the transmission of S. mutans to their children.

Adult↗

PubMed2001

Subclinical chorioamnionitis as an etiologic factor in preterm deliveries.

OBJECTIVE: This study was performed to determine the possible relationship between histologic chorioamnionitis and genital tract cultures and their contribution to preterm delivery. METHODS: The study group consisted of 45 preterm and 37 term pregnancies. Cervico-vaginal cultures were obtained from all patients at admission and placentas were histopathologically evaluated and graded for inflammation of the chorial plate, amniochorionic membrane, umbilical cord and villi. Inflammation scores and presence of pathogenic bacteria were compared between the preterm and term patients. RESULTS: Severe chorionic plate inflammation was present in 35.5% of 45 preterm deliveries as compared to 5.4% of 37 term deliveries. Amniochorionic-decidual inflammation was not present in 14 of the term deliveries (38%), mild (Grade 1--2) in 20 (54%) and severe (Grade 3--4) in 3 (8%) as compared to 14 (31%), 17 (38%), and 14 (31%) in the preterm group, respectively (P<0.05). Pathogenic bacteria were isolated from the lower genital tracts of all patients who had severe chorionic plate (CP) and/or chorioamnionic (CA) inflammation while this was true only in 37.5% of the patients with no or only mild chorionic plate inflammation (P<0.001 for CP, P<0.01 for CA). CONCLUSION: Our results show that pathogenic bacterial colonisation of the cervicovaginal region is closely associated with placental inflammation, preterm labor and cervico-vaginal cultures which may be useful in determining the pregnancies at risk for preterm labor.

Adult↗

PubMed1998

An evaluation of transvaginal ultrasound-guided aspiration of simple adnexal cysts.

We carried out this clinical study to evaluate the benefits the risks of transvaginal ultrasound-guided aspiration in a group of patients. The study group consisted of 22 premenapausal women who were detected as having benign adnexal cysts, based on ultrasound appearances. Before the procedure, all patients were evaluated thoroughly by pelvic examination, transvaginal ultrasound and serum measurements of CA-125. Oestradiol CA-125, follicle stimulating hormone, luteinising hormone and progesterone were analysed in aspirated cystic fluids as well as cytological evaluation. It was concluded that measurements of follicle stimulating hormone, luteinising hormone, oestradiol and progesterone concentrations in cystic fluid had no prognostic significance. But CA-125 levels over 55 iu/ml were likely to predict the recurrence of the cysts. Cytological examination of the aspirated cystic fluids revealed that 21 cysts were benign functional cysts, but one was serous cystadenoma. We observed recurrence following aspiration in five patients (22.7%) who were followed for 6 months. Patients with simple ovarian cysts will benefit from transvaginal ultrasound-guided aspiration by being saved from surgery and its related complications. However, its use should be limited to those masses that appear to be completely cystic with well-defined borders, because of the risk of the intra-abdominal spillage of the contents of complicated cysts.

Journal Article↗