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Biomedical subjects

A V Aleksandrova

Publications and source records attributed to A V Aleksandrova.

At least 19 recordsLinked to original sources

[State of vaginal microbiocenosis and its correction in pregnant women living under conditions of constant exposure to low doses of radiation].

Microflora of the vaginal mucosa was investigated bacteriologically in 44 pregnant women at the pregnancy term of 27-28 weeks. It was shown that in half of the women the vaginal microbiocenosis was within the normal and did not depend on urogynecological diseases in the case histories. In the women with impaired microbiocenosis the level of the impairment depended on gynecological diseases in the case histories. In the pregnant women without urogynecological diseases only slightly pronounced changes in the vaginal microbiocenosis were detected. The prophylactic use of eubiotics (bifidumbacterin and lactobacterin) was not efficient. In the women with urogynecological diseases in the case histories the levels of the microbiocenosis impairment were different. The prophylactic use of the eubiotics was efficient when the changes in the vaginal microbiocenosis were slightly pronounced or marked. When the changes were extreme the prophylactic use of the eubiotics failed.

Adult↗

[Perinatal care for the fetus in women exposed to ionizing radiation after the Chernobyl nuclear plant accident].

Thorough examination covered 114 pregnant women living in the second zone of radioactive pollution (Novozybkov town in Briansk region). Occurrence of miscarriage, late gestosis, intrauterine hypoxia and hypotrophia of fetus was higher vs. control. Laboratory studies helped to reveal underlying mechanisms of the stated conditions which are caused by compromised immunity and changes in fetoplacental system.

Female↗

[The immune status of nonpregnant and pregnant women living constantly under ionizing radiation exposure conditions].

A total of 455 women, both pregnant and nonpregnant ones, permanently living in zones I and II of ionizing irradiation, were examined in 13 months after the Chernobyl Power Plant accident. Monocyte phagocytic activity and humoral immunity parameters were under study. An imbalance of the immunity parameters were characteristic of all the examinees living in zone I: they presented with disordered phagocytic activity of the monocytes, elevated levels of circulating R proteins, reduced production of natural and specific antibodies, changed concentrations of the principal immunoglobulin classes. The immune status of women living in the zone II was found lowered at the expense of reduced phagocytic activity of the monocytes, production of natural antibodies and immunoglobulins, shifted to either sides R protein levels, this necessitating immunocorrective therapy before pregnancy onset.

Accidents↗