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Biomedical subjects

A V Barinov

Publications and source records attributed to A V Barinov.

4 recordsLinked to original sources

[Use of octagam and pentaglobin in the treatment of severe sepsis in the neonatal period].

Many patients with sepsis are immunocompetent. They respond well to standard combinations of antibiotics and cardiovascular support. However, immunocompetent patients, particularly small-for-date newborns, are in need of stronger immune protection. Although the mechanisms due to which antibody preparations yield positive effects are not quite clear, clinical studies carried out in many countries and our own results indicate a high protective effect of intravenous immunoglobulins and necessitate their use at least in intensive care departments.

Age Factors↗

[Changes in the beta 2-microglobulin level during hemodialysis].

The authors studied changes of the beta 2-microglobulin level during hemodialysis with dialyzers AIP-02-02 (cuprophane membrane), E2 (cuprophane membrane), AIP-03-02 (polysulfone membrane), F60 (polysulfone membrane), and hemodiafiltration with dialyzer F60. The following data were obtained. The beta 2-microglobulin level in patients undergoing hemodialysis is approximately 20 times the normal level. No essential fluctuations of the level of this protein occurs during hemodialysis and hemodiafiltration. The cuprophane membrane does not cause increase of beta 2-microglobulin generation during hemodialysis. Standard hemodialysis with the cuprophane membrane and the highly-permeable polysulfone membrane does not lead to decrease of the beta 2-microglobulin level. Hemodiafiltration with the highly-permeable polysulfone membrane is an effective method for the elimination of this protein.

Adult↗