Biomedical subjects

A V Belareva

Publications and source records attributed to A V Belareva.

2 recordsLinked to original sources

PubMedDate not supplied

[Comparative study of E. coli strains producing amino acids].

Transduction of the locus of stability to high threonine concentrations (Thrr) into E. coli str M1 and C600 resulted in enhancements of the amino acid production and retardation of the culture development. Besides the mutation caused increase of the specific activity of glutamate synthase, aspartate kinase and homoserine dehydrogenase. The cells of the mutant strains had poorly developed walls and were smaller than those of the parent strains.

Amino Acids↗

PubMedDate not supplied

[Amination in E. coli strains effectively producing threonine].

The effect of the mutation of threonine and homoserine resistance (thrr) on the activity of the enzymes catalysing the biosynthesis of glutamic acid, glutamate synthase (EC 1.4.1.13) and glutamate dehydrogenase (EC 1.4.1.4), and on the productivity of a threonine-producing E. coli strain obtained by gene engineering was being studied. The resistance to threonine was found to correlate well with the increasing activities of the abovementioned enzymes and with a higher productivity of the E. coli strain.

Culture Media↗