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Biomedical subjects

A V Bhat

Publications and source records attributed to A V Bhat.

28 records · Page 2Linked to original sources
PubMed1982

Response to phenelzine and amitriptyline in subtypes of outpatient depression.

Outpatients with depression and mixed anxiety-depression were treated for six weeks with phenelzine sulfate, amitriptyline hydrochloride, or placebo in a controlled trial. Both active drugs were superior to placebo and were closely comparable in efficacy. Interactions were examined between drug response and classifications based on three different usages of the term atypical depression: additional anxiety or phobic symptoms, atypical functional shift, and nonendogenous depression. Some additional related classifications were also included. There was a tendency for phenelzine to have stronger effects in patients with additional anxiety and without evidence of chronic characterological depression. However, interactions were relatively few. These findings suggest that the two classes of antidepressant affect similar clinical subgroups within the outpatient depressive spectrum, with only relatively weak differences.

Adult↗
PubMed1982

'Personality' and anorexia nervosa - the phobic avoidance stance. Its origins and its symptomatology.

Experience and behaviour in anorexia nervosa is subordinate to the need to achieve and maintain a low body weight in the presence of the impulse, generated by starvation, to forage and ingest, and moreover in the presence of abundant food supplies. The stance is a phobic avoidance one. Normal adult body weight and attendant post-pubertal 'fatness' is feared and avoided through the process of pubertal regression, facilitated primarily by dietary carbohydrate (and fat) avoidance, but otherwise and less effectively by the vomiting/purging syndrome. The maintenance of this stance requires a total commitment of self-control and control of the environment - which are experienced by others as a primary narcissism within the 'patient' and as a tyrannical manipulative attitude to those others.

Adolescent↗
PubMedDate not supplied

The gap in your knowledge: gender on wheels.

Among a group of young car drivers the size of the gap perceived as necessary to allow them to drive their cars through was related to their degree of measured fatness. This relationship extended to measured height and shoulder breadth in women and self-perception of shoulder breadth in men. No relationship could be found with the premenstrual phase in women. These findings may have important social implications.

Adolescent↗
PubMedDate not supplied

Comparison of biochemical characterisation of ICRC bacilli with M. leprae: effect of substrate alteration in the medium.

ICRC-bacilli strain C-44 when grown in Dubos medium of its equivalent, express M. avium taxonomic biochemical characters. Assuming that difference in characters of M. leprae and ICRC bacilli, could be due to 'in vivo' and 'in vitro' milieu, we altered the substrates in the medium. The bacilli grow well in the new medium containing selenium, ferric nitrate, magnesium chloride and deleting Tween 80. The ICRC strain C-44 grown in new medium expressed characters: 9/10 similarity with M. leprae. The 10 day tween hydrolysis reaction in weak but positive. It is probable that 'M. leprae culture isolate', may have acquired 'in vitro' growth potential by recombination with M. avium, an ubiquitous mycobacterium. The M. leprae culture isolate thus may express some characters of both M. leprae and M. avium.

Culture Media↗
PubMedDate not supplied

Dopa-oxidase activity on ICRC bacilli.

Presence of O-phenoloxidase is regarded as M. leprae specific character. This enzyme activity was found to be present in ICRC bacilli, Strain C-44. Though this strain is cultivable 'in vitro', the expression of DOPA-Oxidase activity strongly suggests that it carries M. leprae genome. The ICRC bacilli, therefore, may thus from a group of M. leprae culture isolates, distinct from other known cultivable mycobacteria which do not possess this enzyme activity.

Catechol Oxidase↗
PubMedDate not supplied

Effect of hydrocortisone on arginase activity in ICRC mouse mammary tumours in vitro.

Three fold increase of arginase activity was observed in hydrocortisone treated mammary tumour tissue when compared to the untreated tissue in vitro. No change in succinic dehydrogenase activity was observed. It is likely that arginase present in mammary tumour is due to the presence of mammary tumour virus and it is tempting to speculate that the increase in arginase activity by hydrocortisone may be due to sustained viral production in the presence of hydrocortisone.

Animals↗