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Biomedical subjects

A V Bloch

Publications and source records attributed to A V Bloch.

10 recordsLinked to original sources
PubMed1988

Periappendicitis and diagnostic consequences.

A ten year series of 2660 appendicectomies revealed the microscopic diagnosis to be periappendicitis in 50 cases (1, 9%). In 7 cases the appendicectomy was incidental. Of the remaining 43 patients 21 had salpingitis, 15 had other intraperitoneal inflammation, and in 7 cases no obvious explanation could be found. Peroperatively, periappendicitis was suspected in 3 of the 43 cases, in 18 patients the appendix was judged to be normal and in 17 inflamed. It is important to be aware of the existence of periappendicitis as it often produces signs of intraperitoneal inflammation.

Adolescent↗
PubMed1987

Catamenial pneumothorax.

Recurrent spontaneous pneumothorax associated with the menstrual bleeding--catamenial pneumothorax--is a rare condition. Only 56 cases have so far been described. Two cases are hereby presented, and the different ways of treatment are mentioned. The basic cause of the condition remains unknown.

Adult↗
PubMed1987

Epidemiology of tetanus in Denmark 1920-1982.

Tetanus is still a major health problem in developing countries and still occurs in countries with a high medical standard. To guide planning of future prophylactic programs, incidence and mortality from tetanus in Denmark previous and present prophylactic efforts have been studied. Incidence and mortality from neonatal tetanus decreased in the thirties probably consequently to social and hygienic improvement, and a very marked decrease coincided with the introduction of vaccination against tetanus in 1947. Since 1970 no case of neonatal tetanus has been observed. Mortality from non-neonatal tetanus was reduced markedly in 2 steps, coinciding with an increased use of tetanus antitoxin around 1930 and the introduction of vaccination respectively. The effect of routine vaccination in childhood from 1950 was especially prominent. Tetanus in childhood is now nearly eradicated. A survey of all hospitalized cases of tetanus 1978-1982 showed that the majority of patients were incompletely or never vaccinated, but 10% had a history of complete vaccination. The majority of cases developed from minor posttraumatic lesions, of which only 41% had been professionally treated, and 13% developed from non-traumatic lesions. It is concluded that vaccination programs offering continuous protection are needed for a complete eradication of tetanus. Fatality remains high, in the present series 9.4%, and is mostly due to cardiovascular manifestations.

Adult↗
PubMed1986

Revaccination of adults against diphtheria. II: Combined diphtheria and tetanus revaccination with different doses of diphtheria toxoid 20 years after primary vaccination.

Immunity following diphtheria vaccination in childhood is temporary, and recent outbreaks of diphtheria in adult populations evoked interest in the effect of and side-reactions to revaccination of adults. 237 military recruits were randomly allocated to revaccination with 6 Lf tetanus toxoid or 6 Lf tetanus toxoid combined with 2 Lf or 5 Lf diphtheria toxoid. Side-reactions were recorded one week later, and antitoxin response was assessed after 4 weeks. Protective serum diphtheria antitoxin levels were attained by all subjects receiving diphtheria toxoid containing vaccines. Antibody response was related to dose, indicating a safer long-term protection by revaccination with 5 Lf diphtheria toxoid. All vaccinees, except one without documentation for primary vaccination, attained high tetanus antitoxin levels. Interference phenomena between toxoids were insignificant. Mild local reactions were reported by 22% of the vaccinees. More pronounced local reactions were experienced by 5% and systemic reactions by 3%, independent of vaccine. No serious reactions were observed. Reactions were significantly related to tetanus antitoxin response only. It was concluded that combined revaccination of adults, primary vaccinated around 20 years previously, may be performed without immune assessments.

Adult↗