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Biomedical subjects

A V Butler

Publications and source records attributed to A V Butler.

6 recordsLinked to original sources

Comparison of intradermal and intramuscular hepatitis B vaccination in university students.

Antibody levels following intradermal and intramuscular hepatitis B vaccination were compared in a group of university students matched for age and sex. Intradermal vaccination gave satisfactory antibody levels in females, but much lower levels than by the intramuscular route and an unacceptable failure rate in men. The cost implications of introducing a selective vaccination policy in health care workers are discussed.

Adult↗

Student health during overseas electives.

Ill health is often encountered by travellers. As medical students are encouraged to spend their electives overseas, it was considered worthwhile to study the morbidity experience of University of Bristol medical students and to see whether any additional preventive measures could be identified for them. The findings suggest that the quality of advice could be further improved for medical students undertaking their electives abroad. Additional preventive measures were suggested by the students themselves. The suggestions may also be useful for other groups of travellers.

Health Status↗

Morphological responses of prostatic carcinoma to testosterone in organ culture.

Slices of human prostatic adenocarcinoma obtained by transurethral resection were maintained in organ culture for 4 days. Preservation of histological appearance was good with little evidence of necrosis within the viable tissue. Slices of tumour cultured in the presence of testosterone showed a morphological change to a more differentiated type of neoplasm whereas explants cultured in the absence of steroid hormone, or with stilboestrol diphosphate, showed no change. In the case of a relatively anaplastic tumour, testosterone produced a significant increase in the number of mitotic figures seen.

Adenocarcinoma↗