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A V Dreval'

Publications and source records attributed to A V Dreval'.

At least 19 recordsLinked to original sources

[How physicians and patients look at the problem of obesity].

AIM: To elicit attitude of physicians and population to the problem of obesity; to assess awareness and diagnostic and therapeutic tool. MATERIAL AND METHODS: A questionnaire survey was performed among 384 endocrinologists and 54 other medical professional in 13 cities of Russia. 1405 randomly selected citizens of Moscow (males and females) aged 18-64 years were interviewed according to the standard questionnaire on the telephone. THE RESULTS: Opinion of the physicians. Endocrinologists think that the key factors of weight gain are the following: overeating (81%), hypodynamia (53%), heredity (36%), endocrine pathology (20%), diet rich in fat (18%). Body weight is assessed on the basis of BWI (80%), weight-height tables (38%), Brock's formula (25%), waist and hip circumferences (21%). Endocrinologists believe that obesity should be treated to improve wellbeing (75%), concomitant syndromes (53%), appearance (4%). 92% of endocrinologists recommend a low-calory diet, 82%--physical exercise, 15%--medication, 6%--food additives. Potential patients. 1/3 of city population have overweight. 1/4 of them want to lose weight. Women want to lose weight three times more frequently than men. The proportion of men and women wanting to lose weight is higher at the age group of 40-49 years. Obese subjects more frequently than subjects with normal weight want to lose weight without keeping diet (53 vs 39%) or extra physical activity (38% vs 27%). Women more frequently use methods of losing weight (both registered and unregistered). CONCLUSION: Physicians underestimate the role of obesity in genesis of concomitant diseases, the role of high-calory diets in development of obesity. Most of potential patients have an inadequate attitude to the necessity and feasibility of weight loss, are unrealistic as to methods of losing weight and effectiveness of such methods.

Adolescent↗

[Products with high glycemic indices as factors in the metabolic stress of patients with insulin-dependent diabetes mellitus].

Fifty-five patients aged 15-35 years with insulin-dependent diabetes mellitus lasting 3.8 +/- 1.2 years underwent carbohydrate food loading. Within 2 hours after the meal, at 15-min intervals measurements were made of glycemia, C-peptide, insulin, glucagon, hydrocortisone, blood STH levels. Contrary to foodstuffs with low glycemia indices (GI), i.e. vermicelli, buckwheat, the intake of fast absorbed products with high GI (potatoes, hardtack, bread) stimulates glycemia and residual secretion of the islet cells. Enhanced entrance of gastrointestinal glucose into the systemic blood flow and growing insulinemia aroused glucagon secretion depression. The body responses to the above processes, assessed as metabolic stress, with increasing blood hydrocortisone and STH concentrations.

Adolescent↗

[The immune status in different clinical forms of insulin-dependent diabetes mellitus].

Immune status with reference to the disease duration and genetic factors (HLA-typing) was studied in various clinical variants of insulin-dependent diabetes mellitus. The disease duration appeared the key factor in development of immune deficiency in insulin-dependent diabetes mellitus. Critical immunological values were established (CD5+ cells--1200 in 1 microliter, CD4+ cells--35%, expression of CD5 and antigens HLA class II--110 and 75%, respectively) for septic complications which are highly probable in lower indices. Females with diffuse thyroid enlargement, subclinical hypothyroidism, wide spectrum of antibodies to DNA, antigenic determinants of thyroid gland, hypophysis were found to be a group associated with HLA--DR3 carriage.

Adult↗

[Two-dimensional parameter of the kinetics of glucose (rho-criterion) in the assessment of the efficacy and prognosis of therapy of diabetes mellitus].

The authors describe the results of i. v. GTT in 10 patients with diabetes mellitus before and after a course of hyperbaric oxygenation, in 5 of them the test was repeated. The results of the test were processed with the help of a new type of model of glucose kinetics based on the production of glucose by the liver and its elimination in the test. A new quantitative criterion (the so-called rho-criterion) of a degree of carbohydrate metabolic derangement was introduced for diabetic patients. Its calculation before and after a course of HBO permitted reliable quantitative assessment of the efficacy of sugar lowering therapy in such patients. The new method permitted the assessment of the production of glucose by the liver and the rate of its elimination in i.v. GTT. The mechanism of HBO-action was unraveled (the suppression of glucose production by the liver). Examples of 2 patients with type II diabetes mellitus have demonstrated the efficacy of the rho-criterion in the prediction of a sugar lowering effect of antidiabetic tablets in serious clinical situations.

Adult↗