Biomedical subjects
Publications and source records attributed to A V Fedorova.
An examination was performed in 15 patients who had developed pronounced osteomalacia following gastric resection. The discussion covers potential pathogenetic mechanisms responsible for bone tissue metabolism disorders and approaches to correction thereof.
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Electrolytic imbalance is a frequent finding in malabsorption syndrome. Derangement of calcium metabolism present clinically in different variants is most serious. Some patients develop hypocalcemia manifesting clinically with specific myasthenia, paresthesias, convulsions, hemorrhages, etc. In other variants severe skeletal lesions are seen which may become dominating in the clinical picture though hypocalcemia was absent. Investigation of calcium metabolism, hormonal profile (parathormone, in particular) in malabsorption syndrome can prognosticate and prevent the onset of osteomalacia.
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