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Biomedical subjects

A V Guliaev

Publications and source records attributed to A V Guliaev.

At least 19 recordsLinked to original sources

[Current trends in the diagnosis and therapy of colorectal cancer].

The report deals with the 30-year experience gained by the Department in the treatment of nearly 5,500 cases of tumors of large bowel. Radical surgery for colonic tumor was followed by lethality in 3.0 and 5-year survival-80.8%; rectal tumor resection-5.3 and 58.2%, respectively. Individually-tailored modalities have been devised for a spectrum of cases of colonic wall invasion and metastatic lesions in regional lymph nodes. A choice of sparing, extended and combined surgical procedures vis-a-vis these factors has been developed, the latter offering most advantage. Therapeutic strategies for hepatic metastasis have been worked out on individual basis.

Colorectal Neoplasms

[A rational surgical procedure in diffuse polyposis and multiple primary cancer against a background of polyps of the large intestine].

Under examination there were 292 patients. An analysis of results of treatment enabled the authors to conclude that surgical treatment of patients with diffuse polyposis of the colon is the method of choice. The method and volume of operations must be determined according to the involvement of the colon in polyposis, the age and state of the patients. The best method of surgery is a one-step radical operation-subtotal resection of the colon. Polyps concomitant to cancer of the colon should be ablated before the main operation since their histological analysis can change the volume of the planned radical operation. When choosing the method of surgical intervention for patients with primary-multiple cancer against the background of polyps the total portion of the colon with polyps should be ablated.

Colectomy

[Organization of urgent surgical treatment for complicated colonic cancers in a large industrial city].

The study was concerned with evaluating the results of follow-up of 756 cases of complications of colorectal cancers urgently admitted for surgery to four hospitals of St. Petersburg. Most patients were hospitalized late when complications diagnosed as an acute disease of organs of the abdominal cavity were apparent. Frequent postoperative complications and poor results of treatment were due to advanced age of patients, their grave general condition, concommitant pathologies, frequent errors of diagnosis made before and during hospitalization and lack of a single strategy of therapy. No improvement in the results of treatment of these grave cases can be expected unless the quality of diagnosis and the standards of urgent surgical aid organization are improved and an efficient therapeutic strategy is developed.

Aged

[Specifics of sphincter-preserving surgery in patients with extensive colorectal carcinoma].

The results of combined abdomino-anal resection performed in 56 patients with locally extended cancer of the rectum have been evaluated. Indications for combined and organ-saving operations for extensive rectal cancers have been evolved. If the uterus and even cervix uteri and the vault of the vagina are involved, leaving the lower part of the vagina intact does not affect the radical nature of surgery. Simultaneously, this procedure assures complete rehabilitation of patients because sexual function is not impaired.

Adult

[The efficacy of subtotal distal gastric resection in a modified Billroth-I in cancer].

For the period from 1982 to 1994 subtotal resection of the stomach (96) or gastrectomy (10) was performed on 106 patients by the Bilroth-I method. Efficiency of this method is confirmed by the 5 year survival data, which was determined by dynamic method in 42 patients and was 69.8%. Total postoperative lethality was 6.7%, and gastrectomy-4.2%.

Anastomosis, Surgical

[The surgical treatment of polyps and early forms of cancer of the large intestine].

The article describes the present-day principles of surgical treatment of polyps and early forms of colorectal carcinoma appearing against their background. The investigation performed has shown that all benign adenomas of the colon can be successfully treated by local dissection. Sessile tumors located on the lower- and middle-ampullar portions of the rectum, are liable to endorectal dissection, in pedicular tumors endoscopic polypectomy is most expedient. In cases with carcinoma against the background of adenoma, the main criterion determining choice of the method of surgical intervention is the degree of ingrowth of the tumor into the colon walls. An analysis of long-term results of treatment shows that in carcinoma of the colon developing against the background of adenoma, local dissection is not inferior in efficiency to typical radical operations.

Adenoma

[Cytogenetic and medical genetic research on families with a high predisposition for the development of cancer of the gastrointestinal tract].

Three families suspected of predisposition to tumor development in the gastrointestinal tract have been followed in a medico- and cytogenetical study. According to genealogical analysis, cancer predisposition was confirmed in one family only. However, both specific and non-specific signs of genome instability and possible malignant transformation of cells were identified in members of the other two families.

Adolescent

[Simultaneous intrapleural resection of malignant tumors of the esophagus and cardioesophageal region].

Results of transpleural resection of esophageal and cardioesophageal tumors in 115 patients are discussed. Extensive combined access, formation of invagination anastomosis, preoperative preparation and intensive therapy for correction of homeostasis proved the basic elements of the therapeutic modality. The use of these elements assured lower postoperative lethality (13.9%), particularly, due to surgical complications (9.3%). In patients undergoing extensive combined resection, lethality rate was 10.0%. Intrapleural anastomosis failed in 5.7%.

Adenocarcinoma

[Operative interventions on the urinary tract in combined surgical treatment of cancer of the rectum and sigmoid].

Immediate and long-term results of 28 combined operations for carcinoma of the distal part of the colon with resection of different portions of the urinary system are thought by the authors to justify such interventions even in a real spread of tumour to the adjacent organs. A wider range of resectability does not exert a negative effect on immediate and long-term results of the surgery. Complications due to a wider volume of surgery are noted rarely and never result in lethal outcomes. The incidence of recurrences and metastases in the group of patients subjected to combined operations is the same as compared with typical interventions.

Adult

[Surgical prophylaxis of peritonitis and other suppurative-inflammatory complications following intra-abdominal resections in cancer of the large intestine].

The report discusses a surgical procedure for prevention of pyo-inflammatory complications and peritonitis tested experimentally in 21 rabbits and clinically in 44 patients with colorectal cancers. The frequency of pyo-inflammatory complications was reduced following a reinforcement of anastomosis sutures with autoplastic materials in a procedure employing extraperitonization.

Animals

[Diagnostic errors and inadequate therapeutic tactics in tumors of the large intestines].

The authors observed 21 patients after previous non-radical treatment in other medical institutions. The age of the patients was from 38 to 80. Radical operations were performed on all the patients during relaparotomies. The authors make a conclusion that choice of a rational surgical and curative tactics in colonic tumors was determined individually with special reference to the general state of the patient, careful assessment of the degree of local spread of the tumor. A dogmatic approach is thought to be inadmissible.

Adult

[Laparoscopy in oncological practice].

The results of an analysis of laparoscopy performed in 204 patients for neoplasms of the peritoneal cavity, retroperitoneal space and lung carcinoma are presented. Laparoscopic findings were confirmed by subsequent surgery in 166 cases. These findings in lung cancer patients were compared with the results of a previous radionuclide examination of the liver, laparoscopic diagnosis being confirmed in 66.6%.

Diagnosis, Differential

[A method of treating villous tumors of the rectum].

A method of dissection of the rectum mucosa together with the tumor is described. The mucosa defect is closed by bringing the mucous membrane down and putting stitches on all the circumference. Successful operations were performed on 7 patients.

Female