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Biomedical subjects

A V Iakushin

Publications and source records attributed to A V Iakushin.

15 recordsLinked to original sources
PubMed1995

[Pregnancy and diffuse intestinal polyposis].

A follow-up of 52 pregnant women with diffuse polyps of the colon showed that gestation deteriorated the course of diffuse polyposis and provoked the appearance of the first symptoms of this disease. Diffuse polyposis had virtually no effect on the course of pregnancy and labor. Gestation eventuated in normal full-term delivery in 22 patients, in preterm delivery in 4, in 3 patients cesarean section was performed, in 1 the fetus was extracted with obstetrical forceps, 1 delivery finished with manual detachment and extraction of the placenta. Late spontaneous abortions occurred in 4 women, induced abortions were carried out in various periods in 68 women. Previous extensive resections of the colon undertaken for diffuse polyposis were not a contraindication to surgical delivery.

Colonic Polyps↗
PubMed1994

[Effectiveness of preserving large intestinal segments in surgical treatment of proliferative diffuse polyposis].

Among 390 patients who were operated on in the Research Institute of Proctology for the proliferative form of diffuse polyposis, 242 underwent various types of operations in which polyp-free segments of the large intestine were not resected. In the first 5 postoperative years all 242 patients were examined, in follow-up periods of 6 to 10 years 144 patients (59.5%), in periods of 11 to 15 years 88 patients (36.4%), in periods of 16 to 20 years 28 patients (11.6%), and after 21 years 8 patients (3.3%) were examined. Development of carcinoma in the preserved segments was encountered in 26 patients (10.7%), and intensive growth of polyps for which the preserved segment had to be removed was found in 5 patients (2.1%). There was no significant increase of the risk of carcinoma development in the preserved intestinal segments in patients who previously had a malignant tumor in the resected part of the large intestine. The development of carcinoma and intensive growth of polyps were encountered most frequently in patients in whom the distal parts of the large intestine were not removed during the operation. The obtained data are evidence of the validity of the choice of the volume of the operation based on the endeavor to preserve the polyp-free parts of the large intestine for rehabilitation of the patients.

Adolescent↗
PubMed1993

[Comparative characteristics of various types of operations performed in treatment of diffuse colonic polyposis].

Diffuse polyposis of the large intestine characterized by the development of multiple polyps in it and their subsequent malignant degeneration is one of the most severe disease of the gastrointestinal tract. That it must be treated by surgery needs no proof. However, the volume and the character of the surgical intervention on the large intestine is still a debatable problem. The article discusses the experience in the follow-up of 445 patients for periods of 12 months to 30 years after operation for diffuse polyposis. In 228 patients various segments of the large intestine which were free from polyps were not resected. During these follow-up periods malignant tumors developed in the preserved parts of the large intestine in 10.1% patients and intensive growth of polyps was encountered in 3.5% of patients. The frequency of carcinoma development depended significantly less on the length of the follow-up period and much more on the character of affection of the preserved parts of the large intestine with the polyps.

Adolescent↗
PubMed1991

[The therapeutic procedure for desmoids in patients with diffuse polyposis of the large intestine].

Desmoid was diagnosed in 54 out of 632 patients who had been operated on for diffuse polyposis. The age of patients with desmoid ranged from 18-61 years. Twenty of them had desmoid in the anterior abdominal wall whereas 30--in the small intestine mesentery or retroperitoneal space. Dissection was carried out in 14 out of 18 patients with anterior abdominal wall desmoid. Recurrence was registered in 6 patients. Dissection was attempted in 12 out of 26 patients with intraabdominal desmoid but radical procedure could be performed in 5 only. In a group of 4 patients with synchronous desmoid of both sites, both tumors were removed in one patient only whereas in the other 3--only anterior abdominal wall tumor could be dissected.

Adolescent↗
PubMed1991

[Colectomy with resection of the rectal mucosa and formation of the ileo-rectal anastomosis as an alternative of permanent ileostomy].

A new method for surgical management of patients with diffuse polyposis of the large intestine is described. It was applied in 22 patients with total involvement of all parts of the large intestine in polyps. The essence of the suggested operation consists in preservation of the rectum after its demucosation and the formation of a cecal++-ileorectal anastomosis at the level of the pelvic peritoneum. The operative techniques are described. Experience in various types of intestinal anastomoses with a demucosated rectum as well as the techniques of the most optimal anastomosis are analysed. Retrospective analysis of the results of treatment allowed the authors to conclude that in inclusion of demucosated rectum into the intestinal passage its reservoir and accumulative function is maintained. Follow-up of the patients showed that small intestinal type mucosa regenerates in the rectum after mucosectomy in one third of patients and colonic-type mucosa in the remaining patients. It is pointed out that recurrent growth of polyps in the rectum after adequate demucosation was not encountered.

Adolescent↗
PubMed1987

[Clinical evaluation of the condition of patients with ileostomy operated on for diffuse polyposis of the large intestine].

The work gives a clinical assessment of the state of 116 patients with ileostoma after radical surgery for diffuse polyposis of the colon. Metabolic disorders were noted in 40-50% of the patients with ileostoma for a long time after surgery. More than 60% of the patients do not participate in socially useful labor being the 1 and 2nd group invalids. Persons with ileostoma need dispensary observation, treatment at the hospital including therapeutic measures and reconstructive-restorative operations.

Adolescent↗
PubMedDate not supplied

[A comparative study of nonsurgical methods in the treatment of hemorrhoids].

The authors conducted comparative appraisal of the results of treatment of hemorrhoids in 3 groups of patients at a higher surgical risk in 1989-1990. Group 1 consisted of 79 patients given the traditional nonoperative treatment. Group 2 was made up of 17 patients in whom the hemorrhoidal nodes were ligated by means of latex rings. Forty-three patients of group 3 were treated by the traditional nonoperative methods and, in addition, by infrared photocoagulation, 33 at in-patients and 10 at out-patient clinics. The follow-up periods range from 3 to 12 months. The study showed that nonoperative therapy produced a temporary effect, clinical manifestations of hemorrhoids recurred in 100% of patients. In group 2 59% of patients were cured, which is evidence of the pathogenetic substantiation of the method. The treatment, however, in this group was marked by a great number of complications of an inflammatory character. The best effect was produced among patients of group 3; 37 (86%) patients were cured. Thus, the results of comparative analysis of the efficacy of these methods of treatment in patients at a higher surgical risk showed the advantages of infrared photocoagulation over nonoperative treatment and ligation of hemorrhoids with latex rings. The method of infrared photocoagulation is technically simple, convenient, and can be applied both in in- and out-patient clinics.

Aged↗
PubMedDate not supplied

[Fat absorption in patients with inflammatory diseases of the large intestine and diffuse polyposis].

Radioisotope method with oral administration of 131I-trioleate glycerin and 131I-oleic acid was used to study the absorption of neutral fats and fatty acids in 123 patients with ulcerative colitis, diffuse polyposis of the large intestine, and in 7 patients with ileostomy. It was found that fat secretion with feces was insignificantly higher than the normal and fluctuated within the range of 6.6-11.7%. Steatorrhea did not play a role in the development of clinical symptoms of the disease, and it might be caused by concomitant disorders in the bacterial flora. Slight disorders revealed in the fat absorption should not be considered as an obstacle to their normal use in the diet.

Adenomatous Polyposis Coli↗
PubMedDate not supplied

[The possibility of performing reconstructive-restorative operations in patients with a permanent ileostomy].

An analysis of 69 patients after colectomy with abdomino-anal resection of the rectum for diffuse polyposis was made for the estimation of possibilities to carry out reconstructive-restorative operations with the creation of pelvic small intestine reservoirs. The indications and contraindications for performing such reconstructive operations, main criteria were determined which allowed to estimate the possibility of performing surgical interventions on patients with permanent ileostomy. The significance of each of the criteria is shown for solution of the question of possible performing reconstructive-restorative operations with the formation of pelvic intestinal reservoirs after the previously performed resection of the colon.

Adult↗