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Biomedical subjects

A V Karalkin

Publications and source records attributed to A V Karalkin.

At least 19 recordsLinked to original sources

[Effectiveness of compressive hosiery < > for therapy of chronic venous insufficiency].

Total 40 patients with III grade chronic venous insufficiency underwent conservative treatment with compressive hosiery < >. Patients were divided into 2 groups: the first group used compressive stockings, the second--tights. To objectivize the assessment, all patients underwent volumetry, radionuclide phlebography and regional blood volume measurements. It was shown that in the first group pain syndrome was coped in 73% of patients, edematous--in 60%. According to volumetry data, mean calf volume has reduced by 183+/-41 ml, phlebography has revealed an improvement of muscular-venous pump capacity in 11 patients; in 9 patients it remained unchanged. Blood filling in the affected limb decreased in 16 patients from 10.7% to 8.2% and from 7.5% to 5.3% for thigh and calf, respectively. In the second group an improvement of venous return parameters was more pronounced. Compressive tights relieved pain in lower extremities in 95%, decreased led edema--in 90% of patients. There was significant reduction in calf volume--by 259+/-31 ml to the end of treatment course. Radionuclide phlebography has shown significant improvement of muscular-venous pump evacuatory function and reduction of blood filling in all patients of the second group. In conclusion, results of the study evidenced the effectiveness of compressive hosiery for treatment of chronic venous insufficiency.

Adult↗

[Preoperative care of microcirculatory vessels in patients with lower limb arteriosclerosis obliterans].

The paper analyses diagnosis and treatment outcomes for 20 men aged from 55 to 76 with lower limb arteriosclerosis obliterans. Based on exhaustive laboratory and instrumental diagnostic data the authors conclude that 10-days course of Vazaprostan (20 mkg per day) for patients with IIb stage of chronic lower limb arterial insufficiency yields not only improvement in tissue metabolism, but a reduction of peripheral vascular resistance as well. Thus such therapy can be used for preoperative care before reconstructive vascular interventions in order to reduce the risk of implant thrombosis in early postoperative period.

Aged↗

Radionuclide assessment of the treatment by compression of patients with chronic venous insufficiency.

A study was made of the efficacy of the compression medical tricot in the treatment of chronic venous insufficiency (CVI). To evaluate the treatment by compression, the authors, in addition to the clinical examination, used radionuclide techniques such as examination of the regional blood volumes and phleboscintigraphy. The results of the given work have shown that the compression products under test are effective agents for the treatment of CVI by compression which improves venous return and the patients' quality of life. The data obtained point out that in addition to the lowering of blood filling, the medical tricot influences the interstitial element of the edematous syndrome, leading to the elimination of the latter one. The use of elastic bandages creates the known difficulties (the necessity of the patient training in bandaging, complexity of creating an adequate bandage, quick depreciation). In view of this fact the use of the compression tricot which possesses the fixed grade of compression for a concrete form and stage of CVI is preferable in the therapy of chronic venous diseases.

Adult↗

[Peculiarities of cerebral hemodynamics in angiogenic cochlear vestibulopathy and lipid distress-syndrome (communication 1: ultrasonographic diagnosis].

Arterial and venous blood supply to the brain was studied in 221 patients with angiogenic cochleovestibulopathy and lipid distress-syndrome. Hemodynamic features are described with consideration of cochleovestibular problems and their causes. Alterations in elasticity of arterial wall reflecting systemic processes in atherosclerosis are characterized.

Adult↗

[Radionuclide methods of diagnosis of hepatic dysfunction in lipid distress syndrome and angiogenic cochlear vestibulopathy].

The article presents the results of radionuclide investigations of hepatic dysfunctions in angiogenic cochleovestibulopathies and lipid distress-syndrome. Hepatobiliscintigraphy was made to study bile-synthetizing and excretory function of hepatocytes. The function of reticuloendothelial cells of the liver was studied at scintigraphy. Advantages of radionuclide methods in diagnosis of liver lesions in lipid distress-syndrome are shown.

Adult↗

[Hemodynamic characteristics of the brain in angiogenic cochleovestibulopathies and lipid distress syndrome (Communication 2--radionuclide diagnosis)].

Radionuclide tracing employed to study arterial and venous blood supply to the brain in 100 patients with angiogenic cochleovestibulopathies and lipid distress syndrome has provided information on perfusion of the brain, arterial and venous hemodynamics with reference to the form of cochleovestibular disorders and atherosclerotic defects of extra- and intracranial cerebral arteries.

Brain↗

[Radionuclide tests of cerebral circulation in the assessment of treatment of sensorineural hearing loss].

Examination and treatment results are available for 59 patients with acute and chronic neurosensory hypoacusis. Cerebral circulation was investigated at radionuclide carotid arteriography and radionuclide single-photon emission computed tomography. Arterial flow to the brain, microcirculation of the gray matter and venous outflow from the cranial cavity were studied before and after the course of quantum hemotherapy.

Blood Transfusion, Autologous↗

[Disturbance of liver functions and dysbiosis in patients with lipid distress syndrome and its treatment with lactulose preparation "Duphalac" (lactulose)].

Disturbances of liver's functions and its connection with microflora pathology of large intestine were examined in the patients with lipid dysstress-syndrome. Severe dysbiosis (reduce of light fatty acids level and increase of anaerobe index) was revealed. Efficiency of "Dufalak" (lactulose disaccharide) on liver's functions was estimated.

Adult↗

[The status of cerebral hemodynamics in patients with vertebro-basilar insufficiency syndrome].

The state of venous and arterial cerebral hemodynamics was studied using ultrasonic dopplerography with application of hypo- and hypercapnia, angioencephaloscintigraphy with pertecnetate Tc-99m in 48 patients with syndrome of vertebrobasilar insufficiency. Estimation was performed in patients by the results of neurological and otoneurologic evidence, the data of nistagmography and registration of the truncal evoked potentials. It was found that at early stages of the development of vertebrobasilar insufficiency's syndrome disorders of vasomotor reactivity and disturbances in venous hemodynamics play a leading role in its pathogenesis. Stenosis damages of extra- and intracranial arteries become dominating in subsequent clinical picture.

Adult↗

[The regional hemodynamics in patients with chronic arterial insufficiency of the lower extremities after the transfusion of UV-irradiated autologous blood].

The regional haemodynamics was investigated in 39 patients by indirect radionuclide angiography, dopplerography, determination of the rate of elimination of radiodrugs from the leg tissue before, during and after a course of photohaemotherapy. It was shown that rheological properties of blood, lymph circulation, blood flow rate were improved at all stages of chronic insufficiency of lower extremities of the atherosclerotic and inflammatory genesis.

Adult↗

[Blood fibronectin and liver phagocytic function in peritonitis patients].

The concentration of blood fibronectin and the state of the phagocytic function in the liver was studied in 19 patients with an emergency pathology of the abdominal cavity complicated by the infective-toxin shock and polyorganic insufficiency. Patients with severe abdominal pathology had a considerably decreased level of circulating fibronectin, disturbed phagocytic function of the liver and development of the hypercatabolic state. Hypofibronectinemia was accompanied by polyorganic disorders, systemic bacteriotoxemia and disseminated intravascular coagulation. Causes of hypofibronectinemia and its role in pathogenesis of systemic complications in patients with emergency abdominal pathology are discussed.

Adult↗

[Metabolic disorders in peritonitis: hemodynamic or cellular disorders?].

Systemic and hepatic hemodynamics, gas exchange, acid-base balance in blood from the artery, portal, hepatic and peripheral veins were examined in 113 patients with diffuse peritonitis varying etiologically. In view of adequate tissue perfusion and oxygen transport revealed it is suggested that causes of metabolic derangement arising in peritonitis and responsible for multiple organ insufficiency should be searched into at the level of intracellular metabolism.

Acid-Base Equilibrium↗

[The current diagnostic procedure in chronic pathology of the veins of the lower extremities].

Stepwise (out- and inpatient) examination forms the basis of diagnostic examination tactics in chronic abnormalities of the veins. Noninvasive ultrasonic methods of studying the venous system are preferred. With the gradual formation of groups of patients with an affection of the veins, invasive isotope and angiographic methods are supplemented. The authors emphasize that such examination of patients in stages raises the efficacy and the quality of diagnosis in individuals with chronic venous abnormalities.

Diagnosis, Differential↗

[Hemorheological aspects of the Arvin therapy of acute thromboses of the magistral veins of the lower extremities].

The rheologic blood properties were studied in patients with acute venous thrombosis during Arvin therapy. A marked correcting effect of the agent in removing the hemorheological disorders was demonstrated. It was found that the action of Arvin, linked with reduction of fibrinogen concentration, is attended by a decrease of blood viscosity, diminished aggregation of blood formed elements, and improvement of the functional condition of the microcirculatory bed during the whole course of treatment. The duration of the positive hemorheological effect of Arvin exceeds that in treatment by a complex of antithrombotic agents.

Adult↗

[A present-day approach to surgery for the formation of crossed femoro-femoral shunts in unilateral occlusions of the ilio-femoral venous segment (indications, principles of the surgical technique)].

As distinct from the classical Palme-D'Esperon operation in which the anastomosis is established with the common femoral vein, the authors prefer to form the anastomosis in the region of the saphenofemoral communication in inadequate drainage in the iliofemoral segment in patients with the postthrombotic disease. Seven variants of crossed femorofemoral shunting (CFFS) were carried out. The anastomoses were formed by means of precision techniques; an operating microscope was used when the anastomosis measured less than 5 mm in diameter. The CFFS was found to be patent in follow-up periods of up to 2.5 years in all cases. From analysis of the late-term results of CFFS, the authors claim that functional block of venous drainage from the femoro-iliac segment, rather than anatomical occlusion, is the indication for this operation.

Anastomosis, Surgical↗

[Changes in peripheral hemodynamics in patients with chronic circulatory insufficiency in the extremities after the treatment by reinfusion of UV-irradiated blood].

Reinfusion of the blood irradiated with the ultra-violet rays in patients with chronic insufficiency of the blood supply of the extremities leads to significant increase in the linear and volumetric blood flow rate in the damaged extremities, improvement in the microcirculation, reduction in the blood viscosity. The effect doesn't depend on the genesis of occlusion and degree of the impairement of circulation.

Adult↗