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A V Karlyshev

Publications and source records attributed to A V Karlyshev.

5 recordsLinked to original sources
PubMed1992

Caf1R gene and its role in the regulation of capsule formation of Y. pestis.

A new transcription unit of the f1 gene cluster was found. The DNA sequencing revealed one long open reading frame. Deletion and frame shift mutation analyses have demonstrated the importance of a corresponding gene product for the F1 antigen biosynthesis. A homology of the deduced amino acid sequence with that of AraC family DNA-binding regulators was shown. A potential regulatory DNA region is discussed.

Amino Acid Sequence↗
PubMed1992

A new gene of the f1 operon of Y. pestis involved in the capsule biogenesis.

The DNA sequence determination of the f1 operon between the genes encoding the F1 subunit (caf1) and chaperone-like protein (caf1M) revealed a large open reading frame that codes for a polypeptide similar to some E. coli proteins involved in the biogenesis of fimbria. The deletion and in trans complementation analyses showed that this gene is not necessary for extracellular transport of the F1 subunit but plays a role in the capsule assembly.

Amino Acid Sequence↗