Biomedical subjects
Publications and source records attributed to A V Markin.
Evidence is provided for the value and priority of sanitary and hygienic measures and hygienic education of the population in the prevention of enterobiasis. It is emphasized that preventive work can be successful only when the parents, tutors of preschool institutions and teachers of schools are obligatorily attracted to it.
The efficacy and tolerance of embovin, a new anthelminthic manufactured in Russia, was studied in 60 patients with nematodiases. The results evidence its high efficacy in ankylostomiasis (100%), enterobiasis (100%), and ascariasis (90 +/- 6.4%). The drug was well tolerated in all the cases. No adverse effects on the liver, pancreas, kidneys, as well as on the peripheral blood and urine composition were detected. This recommends embovin for wide use in medical practice.
Presents data on enterobiasis prevalence, medicosocial significance, and epidemiologic features in the former USSR and CIS. Analyzes the causes of ineffective control of this disease. Emphasizes the necessity of simultaneous solution of medical and nonmedical (social) problems. Distinguishes the priority trends in the disease prevention.
Two epidemiologically unrelated outbreaks of trichinellosis were registered in Rostov Province in the November and December of 1984 with 16 patients in the Salsk District and 20 patients in Rostov-on-Don. The course of the disease was characterized by 6-20% of severe and 31-45% moderate forms, respectively. The source of the infection was pork that had not been controlled for Trichinella spiralis. Late diagnosis and inadequate treatment in one case led to a fatal outcome. Economic losses accounted for 490,000 rubles (as of 1985). In spite of energetic prophylaxis measures, the situation in the Rostov Province continues to be serious. In 1989-1992, eighteen cases of trichinellosis were registered in the Salsk District again.
Risk factors for enterobiasis were qualitatively and quantitatively assessed by a questionnaire given to 277 health schoolchildren and 277 schoolchildren who suffered from enterobiasis. A prognostic table was developed for primary screening of risk groups. Preventive measures are recommended in the paper.
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The pupils from Rostov-on-Don were interviewed by a questionnaire on medical helminthology. They were found to poor knowledge in this sphere. They do not observe elementary personal hygienic rules. The ways of improving the hygienic education of pupils.
The paper provides evidence for dividing the prevention of enterobiasis, which is the major human helminthiasis in Russia, into social and medical ones. It proposes to implement 4 directions of medical prophylaxis: behavioral, sanitary and hygienic, functional and biological, and therapeutic and health-improving actions. The paper also characterizes measures underlying each of them.
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The authors examined 20 general educational schools in Rostov-on-Don and identified 8 informative determinants of enterobiasis prevalence among them, such as the frequency of wet cleaning, the number of recreational rooms and gymnasia, over-crowding, the presence of extended-day groups, water supply, shower-rooms in the gymnasia, and shifts of educational processes.
Fifty-six patients subjected to aortofemoral bilateral shunting under prolonged epidural anesthesia are examined. Swan-Gans catheter was used to evaluate central and pulmonary hemodynamics. Ganglionic blocking with pentamine for taxiphylaxis was carried out in 31 patients prior to catheterization of the epidural space. Epidural anesthesia with ganglional blocking is associated with reduced vasodilation and hypotension and attenuates the hemodynamic reactions during clamping and unclamping of the aorta, thus decreasing the incidence of intra- and postoperative complications.