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Biomedical subjects

A V Molchanov

Publications and source records attributed to A V Molchanov.

9 recordsLinked to original sources

[The effect of combined treatment using bicycle exercise with a free choice of the load parameters on the hemodynamics in peptic ulcer patients].

AIM: To study the role of bicycle exercise in combined treatment of gastric and duodenal ulcer, its effect on central hemodynamics and microcirculation. MATERIALS AND METHODS: 94 patients with gastric and duodenal ulcer. 64 patients received conventional antiulcer treatment plus exercised on bicycle ergometer in free regimen of training. 30 patients on the routine treatment only served as control. RESULTS: Doppler echocardiography demonstrated that ulcer patients have eukinetic hemodynamic type more frequently. After combined treatment with bicycle exercise hyper- and hypokinetic hemodynamic types transformed into the eukinetic one, while the eukinetic type remained unchanged. Bicycle exercise contributed to normalization of microcirculation (as shown by conjunctival biomicroscopy), especially in location of ulcer in the duodenum. CONCLUSION: Introduction of bicycle exercise in the treatment of ulcer promoted acceleration of ulcer defects healing, especially in patients with hyperkinetic hemodynamics and duodenal ulcer.

Adolescent↗

[Lipid peroxidation in patients with gastric and duodenal peptic ulcers].

The oxidant and antioxidant status of 42 patients with pyloroduodenal ulcers aged 17-46 years was examined before and after traditional hospital treatment. Total oxidative activity and plasma concentrations of lipid hydroperoxides and malonic dialdehydes were higher in the patients before therapy than in the controls, this increase correlating with the disease duration. Total antioxidative activity and catalase of erythrocytes were decreased only in the patients with ulcer relapses, whereas in the patients with primary ulcers, these values were virtually normal. Erythrocyte superoxide dismutase activity was reduced in all the patients. Low activity of this enzyme negatively correlated with the disease duration. The treatment led to evident clinical and endoscopic improvement but did not completely normalize the increased level of free-radical oxidation parameters and decreased total antioxidative activity and erythrocyte catalase and superoxide dismutase activities.

Adolescent↗

[Actinic reticuloid].

A patient with a rare dermatosis, actinic reticuloid, is described. Differential diagnostic characteristics of this condition as against mycosis fungoides are presented, and rational therapy of such patients is discussed.

Diagnosis, Differential↗

[Combined therapy of interstitial cystitis using the "Aeltis-Synchro-02-Iarilo" device].

Multiple modality therapy of interstitial cystitis (IC)--the disease characterized by nicturia, pelvic pains, imperative pollakiuria--is considered. As IC nature is not well known, its treatment remains empiric. Among the underlying causes, most probable are autoimmune, allergic, infectious, neurological, vascular. Therefore, the treatment should be multi-modality. Most usable now is combined chemotherapy. Perspective is also IC treatment with medicines in combination with physiotherapy (electromagnetolaser AELTIS-SYNCHRO-02-YARILO"). Endovesical electrophoresis can be also applied.

Adult↗

[Bicycle exercise in the free load regimen and hemodynamics in inpatients with ischemic heart disease].

Hypokinesia is not an independent risk factor of ischemic heart disease (IHD) but it contributes to progression of this disease because of a positive correlation with such risk factors as arterial hypertension, dislipoproteinemia, obesity, hyperinsulinism, diabetes mellitus type 2. This dictates the necessity to add exercise to pharmacotherapy of IHD. Combined treatment of IHD including bicycle exercise in the free load regimen significantly improves cardiac pump function--a 32.0 and 34.7% mean rise in stroke index and ejection fraction in patients under 60 years of age, respectively. The above rise does not depend on the initial condition of hemodynamics. There are cases when the increase is the highest in patients with the least baseline indices showing the presence of adaptive reserves which realize in physical training. The patients treated had no complications. Thus, use of the above bicycle exercise in IHD patients can be recommended for hospital rehabilitation.

Aged↗