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Biomedical subjects

A V Nedostup

Publications and source records attributed to A V Nedostup.

At least 19 recordsLinked to original sources

[State of autonomic regulation in patients with mitral valve prolapse and dysfunction of sinus node].

This study was made of 62 patients with idiopathic mitral prolapse, 17 patients with vagus sinus dysfunction and 8 patients with combination of the above disorders. Clinical, psychological and electrophysiological examinations revealed in all the patients psychovegetative syndrome with paroxysmal and permanent vegetative disorders, anxious-hypochondriacal and anxious-depressive conditions. Vegetative disorders were characterized by definite discoordination of vegetative regulation manifesting as hyperactivity of suprasegmental vegetative structures and insufficiency of both sympathetic and parasympathetic vegetative regulation.

Adult

[The use of hemosorption and plasmapheresis for treating cardiac arrhythmias (a preliminary report)].

The authors present pilot experience in extracorporeal blood purification (hemosorption, plasmapheresis) aimed at correction of cardiac arrhythmia. Seven responders of 8 patients treated had less frequent episodes of cardiac fibrillation the severity of which decreased, they suffered no more from high-grade extrasystoles, were put on reduced doses of antiarrhythmic drugs. The response is attributed to improvement of blood rheology and elimination of arrhythmogenic substances.

Aged

[Clinical efficacy of cefixime (results of multicenter trials)].

Multicentre trials of cefixime (Cefspan, Fujisawa Pharmaceutical Co., Ltd., Japan) were performed in 1992. The trials involved 137 children and 269 adult patients with inflammatory infections of the respiratory organs and urinary tracts and otorhinolaryngologic affections. Positive clinical and bacteriological results of the trials were stated in 76-90 per cent of the cases. The adverse reactions such as skin eruption and dyspepsia were rare and did not require the specific treatment.

Adolescent

[A comparative evaluation of the electric impulse treatment of atrial fibrillation based on the data from 2 clinics. 2. The late results].

Long-term results of electroimpulse treatment for cardiac fibrillation in 1292 patients performed in cardiological clinics of Moscow and Kaunas have been compared. It is shown that more strict selection, longer preparation for the impulse exposure may secure a significant decrease in the number of the fibrillation recurrences both 1 and 6 months after recovery of the normal rhythm.

Atrial Fibrillation

[A method of choosing maintenance anti-arrhythmia therapy after sinus rhythm restoration in patients with a permanent form of atrial fibrillation].

The authors suggest a new method of choice of the drug (quinidine or cordarone) for the maintenance antiarrhythmic therapy after sinus rhythm recovery in patients with permanent atrial fibrillation, in patients with rheumatic heart disease and coronary heart disease. The method is based on the formalized prediction of the results of cardioversion and on the distinguishing groups with a good and bad prognosis. In the former group, both drugs can be administered, in the latter group, it is desirable that cordarone may be used.

Amiodarone

[Spontaneous restoration of cardiac rhythm in patients with a persistent form of atrial fibrillation].

A total of 15 patients with spontaneously arrested sustained atrial fibrillation (its duration 7.0 +/- 1.6 years) were followed up. After termination of atrial fibrillation, all the patients had signs of the sick sinus syndrome (profound sinus bradycardia, pacemaker migration, inferior atrial and atrioventricular rhythms). Thirteen of 15 patients suffered from rheumatic heart disease, nine of them had severe heart failure. Four patients immediately died. An atrial fibrillation relapse occurred in the immediate period in most cases, and rhythm recovery was unaccompanied by the improvement of the patients' condition.

Adult

[The prognosis of the late results of electroimpulse therapy for atrial fibrillation in ischemic heart disease patients].

The deciding rule has been derived of predicting long-term results of electropulse therapy of permanent atrial fibrillation in patients with coronary heart disease. During checking with the prospective material, the prediction as regards preservation of the sinus rhythm up to 6 months turned out correct in 93% of cases. The deciding rule is based on the commonly available clinical parameters. Work with that rule does not require the use of computers. Prognosis obtained with the aid of the given rule appeared significantly more accurate than that determined by the physician specialized in the field of cardiology.

Adult

[A comparison of the efficacy of quinidine and kordaron as agents to stabilize the recovered sinus rhythm in patients with the permanent form of atrial fibrillation].

The efficacy of chinidine and cordarone as agents preventing the recurrence of the disturbed sinus rhythm was studied and compared on a material of 459 patients with permanent atrial fibrillation eliminated by electropulse therapy. The sinus rhythm was preserved significantly better in a group of patients given cordarone as a preventive agent, which is confirmed with the aid of a multidimensional statistical analysis as well as an analysis of "competing hypotheses".

Adolescent