PubMed HealthSearch

Biomedical subjects

A V Novikov

Publications and source records attributed to A V Novikov.

At least 19 recordsLinked to original sources

Laser-induced fluorescence line narrowing of native porphyrins in animal tissue.

Using monochromatic laser excitation, narrowing of the porphyrins 0-0 fluorescence line in rat muscle tissue to a width of 50-70 cm-1 at 4.2 K is observed. Fluorescence spectra at different excitation wavelengths and excitation spectra are measured. Fluorescence line peak follows the shift of the excitation frequency. Several of the most prominent vibrational frequencies of porphyrins in the excited electronic state are determined.

Animals

[Genetic approaches to Itsenko-Cushing disease].

107 patients with Itsenko-Cushing disease were examined for heredity: family history was analyzed in 75 cases, dermatoglyphics was assessed in 44 cases, I- and II-class HLA antigens were studied in 68 cases. The patients were found to have hereditary loading both by Itsenko-Cushing and other diseases (hypertension, atherosclerosis, autoimmune disorders). Clinico-genealogical evaluation made it possible to identify forms of the disease which are inherited autosome-recessively and autosome-dominantly. However, in the majority of patients the disease onset had multifactorial nature, as there were HLA-antigen associations by DR4, DR5, DR7, DRw53, DQw3. Pilot experience with genetic study of the disease showed its genetic determination in some forms, its association with hypertension and atherosclerosis, approaches to prevention, prognosis, classification. Practical recommendations on detailed family history collection in patients with Itsenko-Cushing disease have been developed.

Adult

[Method of studying the opinion of patients on the operation of an ambulatory rehabilitation center].

A questionnaire has been developed to study the extent of patient's satisfaction with rehabilitative treatment under conditions of a specialized rehabilitation centre. 100 neurological and traumatological patients were surveyed by means of questionnaires. A technique for the data obtained processing has been suggested which permitted one to identify the main factors lessening the extent of satisfaction with the outcomes of treatment. A comparative analysis was made of patients' and physicians' opinion on the quality of treatment provided. The comparison of questionnaire data provided by patients and objective indicators of health institution performance is aimed at increasing the level of health care delivery.

Ambulatory Care Facilities

[Methodological approaches to the evaluation of the effects of environmental pollution on morbidity of the population].

A method is proposed which is based on the comparison of calculation coefficients estimated by eliminating the actual rates of morbidity resulting in temporary disability among workers and employees of some branches of national economy residing in different territories. Calculation algorithms are provided, the use of which is illustrated by relative and specific examples. It is demonstrated that the method based on the evaluation of present information systems is fully acceptable for assessing the influence of environmental pollution on the morbidity of able-bodied population.

Absenteeism

[Thermographic examination of patients with neurologic manifestations of lumbar osteochondrosis].

The article deals with thermography data collected for 94 patients with different clinical signs of lumbar osteochondrosis (reflex, radicular, vascular, radiculo-spinal). The features of thermograms were described as depending on the leading clinical syndrome of the disease. A lack of direct correlation between the severity of the pain syndrome and thermoasymmetry was registered. The data suggest wider use of the diagnostic capacities of IR-imaging techniques in patients with vertebrogenic pathology.

Adult

[Changes in the resting ECG in males with impaired carbohydrate tolerance of different degrees without clinical symptoms of ischemic heart disease and arterial hypertension].

The resting ECGs were analyzed in males aged 20-60 years with various tolerance to carbohydrates. There were statistically significant differences between the values characterizing the functions of automatism and conductivity on the resting ECG in patients with diabetes mellitus without any clinical symptoms of coronary heart disease (CHD), arterial hypertension, cardiac failure and other chronic diseases and in healthy males with the normal tolerance to carbohydrates. in patients with borderline impairments of carbohydrate tolerance (CT), these parameters occupied an intermediate position between the corresponding values in patients with diabetes mellitus and in subjects with the normal tolerance to carbohydrates. During the mass screening of the population the complex of the examinations conducted should include the methods of monitoring carbohydrate metabolism in order to identify individuals with CT impairments who are at risk of developing both CHD and diabetes mellitus.

Blood Pressure

[Effect of propranolol on the indicators of carbohydrate metabolism and lipid transport in patients with diabetes mellitus type 2].

The paper is concerned with some data on the time course of indices of carbohydrate metabolism and lipid spectrum in patients with type II diabetes mellitus with concomitant CHD or arterial hypertension during therapy with mean doses of propranolol. The course treatment with propranolol resulted in the deterioration of carbohydrate metabolic indices and unfavorable shifts in the lipid spectrum of some patients. Patients on insulin therapy might demonstrate a significant decrease in the blood sugar level after physical exercise. The results obtained indicate the necessity of control over indices of carbohydrate and lipid metabolism in patients with type II diabetes mellitus during propranolol therapy.

Adult