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Biomedical subjects

A V Piskarev

Publications and source records attributed to A V Piskarev.

At least 19 recordsLinked to original sources

[Enzymatic differentiation and absorptive capacity of the epithelium of small intestine macrocolonies].

Research into the activity of the enzymes invertase, gamma-amylase, alkaline phosphatase in the macrocolonies of the rat small intestine has shown that each macrocolony has stringently individual functional properties and the predominance of one of the enzymes. The data have been also obtained, indicating different rate of lysin and leucin absorption by the macrocolony epithelium of the small intestine. The results prove the existence of a definite functional differentiation of epitheliocytes (macrocolonies) arising from the same stem cell of the intestinal epithelium.

Alkaline Phosphatase↗

[Radioprotective effect of pyrazolone derivatives].

The intraperitoneal injection of analgin (1000 mg/kg), antipurine (400 mg/kg), amidopyrine (100 mg/kg) 3 hours before the irradiation of mice in a dose of 800 R led to survival of 30 to 45% of the animals (against 12.5% in control) and to increase in the average duration of life of the animals that perished. 80-95% of mice survived the period of "intestinal deaths" (the 7th day after the irradiation) after combined prophylactic use of purasolone derivatives and cystamine before the irradiation of these animals in a dose of 1050 R. The radioprotective effect of pyrasolone derivatives given in therapeutic doses was less pronounced.

Aminopyrine↗

[Decrease in bacterial toxemia after radiation-thermal injury in the restoration of motor-evacuation function of the gastrointestinal tract].

Experiments were conducted on male Wistar rats to study the possibility of restoration of the motor-evacuative function (MEF) of the gastrointestinal tract (GIT) after radiothermal injury (irradiation with a dose of 6 Gr+Stage IIIb burn). Changes in the development of bacterial intoxication in the injured organism were analysed. Restoration of GIT MEF in the injured rats leads to simultaneous diminution of the degree of bacterial toxemia which plays an important role in the pathogenesis of radiothermic injury.

Animals↗

[Changes in small intestine function after radiation and thermal injury].

A study of the small intestine functions after radiation and thermal affection of rats has revealed an inhibited absorption of carbohydrates, fats and proteins. The disturbance of the resorption of these substances results from a change in the motor-evacuator function and a decrease in the activity of the appropriate enzymes in the small intestine mucosa.

Animals↗