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Biomedical subjects

A V Pugaev

Publications and source records attributed to A V Pugaev.

At least 19 recordsLinked to original sources

[Surgical treatment of purulent complications of acute pancreatitis].

The results of the treatment of 34 patients with purulent lesions of the pancreas and parapancreatic fat are presented. The surgical policy is proposed, depending on the location of purulent cavities. The policy includes evaluation of the rate of the purulent process dissemination, dissection of the necrotic and nonviable tissues and adequate drainage of the parapancreatic fat with subsequent aspiration (in 48-72 hours) and irrigation of the cavities starting from the 5-7th day. The blood vessels, located in purulent zone should be ligated. 26 of 34 patients have been successfully discharged. Postoperative enteric fistulas have developed in 3 patients.

Acute Disease↗

[Conservative treatment of complete distal pancreatic fistula].

36 patients with external pancreatic fistulas have been analysed. Complete distal fistulas have been demonstrated in 23 patients. Pancreatic fistulas were caused by trauma of the pancreas (8), acute pancreatitis (10), surgical treatment of the pancreatic cancer (5). The study of endocrine and exocrine functions has demonstrated that in 2-3 months a gradual decrease of exocrine function of the distal segment of the pancreas takes place. This segment is drained through the fistula. The processes of fibrosis and atrophia are major factors of such a decrease. The method of "biological" filling based on the results of the study of fistulas' pathogenesis, usage of a rational therapy and capillary drain appeared to be the most effective in treatment of this complication. It provided a gradual formation of a narrow fistula and its closure with granulations.

Adolescent↗

[The effect of the duration of dynamic intestinal obstruction on the occurrence of suppurative complications in acute pancreatitis].

Longer periods of the dynamic intestinal obstruction in acute pancreatitis are responsible for more frequent purulent complications. Laparotomy in acute pancreatitis is responsible for a longer duration and greater degree of the dynamic intestinal obstruction and more frequent purulent complications. Early administration of cooled electrolytic solutions into the jejunum, according to the authors' data, reduced the periods of the dynamic intestinal obstruction and decreased lethality.

Acute Disease↗

[Microbiological study of peritoneal exudate in acute pancreatitis of diverse severity].

Bacteriologic investigation of peritoneal exudate was performed in 62 patients, including 19--while performing laparotomy and 43--laparoscopic investigation. In the enzyme toxemia phase the exudate was infected in 19.3% of patients. In acute pancreatitis of mild degree the peritoneal exudate was sterile in all of the patients, while in middle degree and severe one the microorganisms were discovered in peritoneal exudate accordingly in 23 and 33.3% of patients. Appearance of obligate anaerobic microorganisms in peritoneal exudate in the first phase of an acute pancreatitis presents the risk factor for suppuration of necrosis foci.

Acute Disease↗

[The use of enteral tube feeding in patients with gastric and duodenal peptic ulcer].

The authors used enteral tube feeding with a multicomponent balanced mixture "Ovolakt" in complex treatment of gastric and duodenal ulcer in 69 patients among which 42 had complicated forms (stenosis, penetration, bleeding) and 27 had no complications. In establishing the diagnosis laboratory tests and radiological and endoscopic examination were conducted. The gastric secretory function was studied by intragastric pH-metry and pH-chromoscopy conducted during enteral feeding and in dynamics after it was ended. In most cases of cicatrization of the gastric and duodenal defects, hypo- and hyperchlorhydria respectively, persisted. Among 42 patients with complicated course of peptic disease, 21 were treated by operation and 19 received nonoperative treatment. The postulcer cicatrix formed 2-3 weeks after enteral feeding was ended in 27 cases of uncomplicated peptic ulcer and in 19 patients with complicated ulcers who were given nonoperative treatment. Complications after operative treatment were not encountered. Patients not treated by operation spent 20-30 days in the hospital.

Adult↗

[Prospects of intraoperative dynamic cholangio-manometry by tensor detectors with graphic recording of pressure function].

Intraoperative cholangio-manometry with a miniature tensor sensor and graphic recording of the results were conducted to study the function of the major duodenal papilla in 53 patients. A periodical activity of the ampulla of the papilla was revealed, which was characterized by certain values of the peak and basal pressure, and duration of contraction and relaxation periods. The numerical values and the pattern of the pressure curve differed in patients with obstructive cholecystitis, biliary pancreatitis, and a concrement incarcerated in the ampulla of the papilla. The informativeness of the study increases with the use of the glucagon test.

Adult↗

[Transumbilical cholangiostomy].

The authors suggest a method for decompression of the biliary system in obstructive jaundice with bile drainage blocked at a high level. The method consists in catheterization of the bile ducts through the lumen of the umbilical vein dilated by bougienage. The efficacy and safety of the method were proved in 15 cases. No complications were encountered.

Adolescent↗

[Endoscopic placement of a jejunal tube and a method of conducting enteral feeding with special mixtures].

The endoscopic placement of a nasoenteral probe for jejunal nutrition can be brought about by four main technical modes: conducting the probe through the biopsy canal of the endoscope, placement along the string, parallel introduction with the endoscope and combination of the above methods. An emulsion product containing 1 kkal/ml, macro-, microelements, vitamins was used for the enteral nutrition. Three main methods of enteral probe nutrition were used depending on specificity of the main disease, character of functional disorders of the intestine and the presence of inflammation in digestive organs.

Digestive System Diseases↗

[Prevention and treatment of complications of acute pancreatitis].

Results of treatment of 156 patients with acute pancreatitis (with the first attack of the disease) were analyzed. These patients had 284 early and 76 late complications of the disease. Causes of the complications observed are discussed. The authors describe their methods of conservative and operative treatment and give practical recommendations for prevention of complications of acute pancreatitis. The complex treatment of acute pancreatitis with special attention to prophylactics and improved methods of treatment of the complications is shown to give better results.

Acute Disease↗