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Biomedical subjects

A V Spiridonov

Publications and source records attributed to A V Spiridonov.

5 recordsLinked to original sources

[Load tests in silent myocardial ischemia and latent heart failure in patients with IHD and intermittent claudication].

244 patients with ischemia of the lower limbs were treated surgically in the specialized cardiovascular center. No lethal outcomes were reported because previously derived algorithm of detecting silent myocardial ischemia in patients with intermittent claudication and load tests (bicycle ergometry and drug stress tests) had allowed the surgeons to ascertain the extent of coronary damage and detect subclinical cardiac failure. Valid assessment of cardiac factors enabled the right choice between surgical and therapeutic methods and staging of the procedures.

Arteriosclerosis↗

[The significance of modifying factors in evaluating the effect of radionuclides].

The authors provide the data obtained in experimental animals, pertaining to the influence of certain modifying factors on metabolism and biological effects induced by radioactive isotopes of iodine, by transuranium elements and beryllium. Out of all the modifying factors investigated, the form of the introduced compound and age turned out the most significant ones.

Aging↗

[Prospects for determining age from human soft tissues (a morphometric study)].

Biometric studies of the aorta, endocrine glands (testes, prostate, and thyroid), and x-ray examination of the hands from 427 corpses of men and women aged 17-89 years helped formulate equations of paired and multiple linear regression for the diagnosis of age. The difference between biological and passport age is significant if the diagnosis is made on the basis of a single object or single sign. Complex use of several objects described by many signs is recommended; in this case the confidence intervals is no more than +/- 4.09 years.

Adolescent↗

[Radionuclide biokinetics as a function of the age of experimental animals].

Behaviour of radionuclides with different distribution types in the organism of animals of various ages was studied. Depending on the age of experimental animals, an essential difference in biokinetic parameters such as coefficients of absorbtion from gastro-intestinal tract, distribution and retention levels in critical organs, retention and excretion rates of radionuclides was found.

Administration, Oral↗

[The forensic medical assessment of age-related changes in the thyroid].

The problem of assessing the age of unidentified corpses remains a pressing one. Relevant published data is reviewed in brief. This study was aimed at assessing the possibility of using quantitative morphometric parameters of thyroid involution for forensic medical evaluation. The method of using these parameters and their mathematical processing is described. An optimal model is selected for assessing the biological age from two parameters, the percentage and diameter of follicles; this model permits the diagnosis of age with an accuracy of 88%.

Adolescent↗