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Biomedical subjects

A V Strotskiĭ

Publications and source records attributed to A V Strotskiĭ.

9 recordsLinked to original sources
PubMedDate not supplied

[The dispensary care and work disability expertise of bladder cancer patients following cystectomy].

A question of the principles and methods of medical prophylactic survey in patients with bladder cancer who have undergone cystectomy with subsequent ureterosigmoid anastomosis and ureterocutaneostomy is not currently developed. On a basis of 79 follow-ups of patients with bladder cancer after cystectomy, a procedure of prophylactic survey in the setting of regional oncologic dispensary and district polyclinic was worked out. It is stressed that it is necessary to follow up the patients for a possible relapse and metastasis development as well as complications of the upper urinary tract and kidneys and metabolic shifts (acidosis, dyselectrolytemia). From this viewpoint we propose a scope of essential examinations during the medical prophylactic survey. Our results of the patients follow-ups after cystectomy are also given. Recommendations for the patients working ability estimation are proposed and it is noted that the estimation is to be carried out on a strictly individual basis because the patient's rehabilitation depends on many factors. But the main principles of such patients' working ability estimation are submitted in schemes of a working ability examination. They depend on the stage of the process and on the method of urine drainage after cystectomy.

Ambulatory Care↗
PubMedDate not supplied

[The content of the carcinoembryonic antigen in the blood serum of patients with bladder tumors at various stages of combined treatment in relation to the disease stage].

Serum level of a tumor marker, carcinoembryonic antigen (CEA), was examined in patients at different stages of vesical cancer before and during combined treatment, including preoperative large-fraction radiotherapy and surgery. Sixty patients with histologically documented vesical cancer, stages T1N0M0, T2N0M0, T3N0-1M0 and T4N0M0 were investigated. All patients underwent large-fraction radiotherapy prior to surgery. Transvesical resection of the bladder wall with the tumor or cystectomy was performed within 24-72 hrs after radiation exposure. Serum CEA was measured repeatedly (on admission, after preoperative radiotherapy, postoperatively, at discharge) by enzyme immunoassays. It is demonstrated that CEA variation in the course of combined treatment depends on the stage of cancer. CEA level decreased after preoperative large-fraction radiotherapy in patients with T1, T3 and T4 stages of cancer, and increased in patients at the T2 stage. Following combined treatment, serum CEA was reduced two-fourfold as compared to pretreatment values in patients with first, third and fourth stages of vesical cancer, an evidence of the adequacy and radical quality of treatment and a favorable predictive sign.

Biomarkers, Tumor↗