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Biomedical subjects

A Varga

Publications and source records attributed to A Varga.

At least 19 recordsLinked to original sources
PubMed1995

[15-year echocardiographic follow-up of acromegalic patients].

An echocardiographic follow-up of 25 patients (pts) was performed, after the first examinations in 1978-1979. 15 pts have died in the last 15 years (Group 1), while 10 still living (Group 2). In Group 1 either the impaired global left ventricular at the time of the first echocardiography predicted a high mortality i.e. there were only two pts with normal echocardiographic findings. The other 6 acromegalic pts with a "normal heart" have survived. The left ventricular hypertrophy of pts in Group 2 was observed to increase during the 15-year follow-up, because of the development of systemic hypertension. In conclusion, the echocardiographic findings are of a good predictive value in estimations of the survival rate in acromegalic pts.

Acromegaly↗
PubMed1995

[Angiologic screening of postal workers].

The authors present the results of an angiological survey conducted on 500 postal workers (374 males, 126 females, mean age 43.4 years). All subjects were interviewed about the history of cardiovascular diseases and risk factors. Clinical angiological examination, measurement of Doppler and oscillometric index, plethysmography (rest flow, peak flow, time to peak flow) were carried out. In 8.4% of the subjects (42 cases; 32 males, 10 females) peripheral arterial circulatory disturbance (PACD) was detected, seven of them (16.6%) had intermittent claudication. Frequency of smoking, hypertension and manual working proved to be significantly higher in the group of subjects with PACD than without PACD. Dorsalis pedis and/or tibialis posterior arteries were not palpable in seven (16.6%) of the patients with PACD, and in 25 (5.45%) of the subjects without PACD. The mean values of Doppler index, oscillometric index, peak flow, time to peak flow differed significantly between PACD "positive" and "negative" groups.

Adult↗
PubMed1995

Early and late complications of uretero-enteric anastomosis.

The authors report on early and late complications of uretero-enteric anastomosis. The results of pre- and postoperative US evaluations in 67 patients with urinary diversion using isolated bowel segment are reviewed. Ultrasonography (US) is the first method of choice in recognizing postoperative complications. Authors observed 5 early and 5 late complications directly related to the uretero-enteric anastomosis operation. Possible treatment modalities and the role of US guided nephrostomy are discussed.

Anastomosis, Surgical↗
PubMed1994

[Comparative evaluation of dipyridamole and dobutamine 2-dimensional echocardiography in ischemic heart disease].

Dipyridamole and dobutamine stress were performed in the same 41 angiographically controlled patients. Both tests were followed by 2 dimensional-echocardiography. The dose of dipyridamole was 0.56 mg/kg/4 min. or 0.84 mg/kg over 10 min., while the dose of dobutamine was 10-20-30-40 and 40 micrograms/kg/min. over 3 min. each step. In addition, to reach the submaximal heart rate 0.25 mg/min Atropine was also injected for 4 minutes in 13 cases. One vessel disease was found in 15 cases, and 2 vessel disease was in 2 cases. The number of coronarography negative cases was 24. The sensitivity, specificity, positive and negative predictive values for both tests were 70%, 91%, 85% and 81%, respectively. False positive results were observed in 2 cases and false negative ones were found in 5 cases, mainly at left anterior descendent stenosis. There was a good agreement between the wall motion abnormality and the anatomic localization of stenoses. Both non-invasive tests are suitable for the diagnosis of ischaemic heart disease.

Adult↗
PubMed1992

Some possible gynaecological indications for peripheral antidopamine therapy.

The effect of the dopamine receptor blocking domperidone (Motilium) has been examined in 73 gynaecological patients in a wide indication field. The treatment was successful in controlling dyspeptic symptoms of different origins, nausea-vomiting of different etiologies, climacteric flushes, and in the prevention of migraines in 67.1% of the cases. Partial response was obtained in 19.2%, and no response in 13.7% of the cases. According to the opinion of the authors the gastrokinetic and antiemetic effect of domperidone is of high value, the use of the drug may be attempted as a monotherapy or an adjuvant therapy for the prevention of migraine and the treatment of climacteric flushes.

Adult↗
PubMed1991

[Diagnosis of femoral pseudoaneurysm and factors contributing to its incidence after heart catheterization].

Two-hundred patients who underwent heart catheterization between 30 November 1989 and 30 September 1990, were followed up to establish the frequency of the vascular complications (mainly femoral pseudoaneurysm) of the procedure. Factors were evaluated which may promote the occurrence of femoral pseudoaneurysms. This complication was diagnosed in 6 cases. Two-dimensional and Doppler echocardiography (conventional and colour-coded) played an important role in the diagnosis. Systemic hypertension, anticoagulant therapy, obesity and technical difficulties (multiple punctures and catheter guidance problems) proved to be factors promoting femoral pseudoaneurysms. Serial echocardiograms revealed a tendency to spontaneous healing even in cases of relatively large pseudoaneurysms.

Aneurysm↗
PubMed1991

[The significance of the dipyramidole echocardiography test in ischemic heart disease].

The diagnostic value of the dipyridamole echocardiography test was investigated in 46 patients who underwent coronary angiography due to suspected ischaemic heart disease. Twenty-two of 46 patients were found to have a narrowing of at least 70% one vessel. Twenty-four hour ECG monitoring was also performed on 19 patients on the day of the dipyridamole test. The sensitivity and specificity of the two-dimensional echocardiography test (new wall motion abnormality) were 72.7% and 62.5%. The ECG (V2-5-9) had a low sensitivity during the test (43.8%). Good agreement was found between the localization of the wall motion abnormalities and the site of anatomic narrowing in the ischaemic group. No significant ventricular arrhythmias were detected, and the sensitivity and specificity of ST-T changes were found to be 62.5% and 54.6% by means of Holter monitoring. The dipyridamole echocardiography test proved to be a suitable noninvasive method for the diagnosis of ischaemic heart disease and for the selection of patients for coronary angiography.

Coronary Angiography↗
PubMed1991

[Doppler echocardiography in the examination of normally functioning artificial mitral and aortic valves].

Patients with prosthetic valves were investigated by Doppler echocardiography in 902 cases between November 1987 and February 1990. The parameters of 209 of 344 mitral and 258 of 299 aortic prosthetic valves were evaluated. No significant correlation was found between the type of aortic or mitral prosthetic valves and the measured gradient. As concerns the size of the valve and the measured gradient, a close correlation for aortic valve replacement was detected. For a normally functioning mitral prosthetic valve, a maximum early diastolic velocity of less than 2 m/s (16 mm Hg gradient) and a pressure half-time of less than 130 ms (mitral valve area 1.8 cm2) were characteristic. In cases of aortic valve replacements, the maximum velocity was less than 3 m/s (36 mm Hg gradient), except for the small-diameter valves. More than 95% of the cases met these criteria. (Even if small-diameter valves were included, a maximum velocity of more than 3 m/s occurred only in 8.9%.) Doppler echocardiography is a suitable tool for detecting normal prosthetic valve function, while colour Doppler allows the optimal alignment of jet direction and Doppler beam.

Aortic Valve Insufficiency↗
PubMed1991

[Systemic thrombolysis in acute obstruction of an artificial valve].

Prosthetic valve thrombosis is a characteristic, but fortunately not frequent complication of surgical valve replacement. Its occurrence may lead to haemodynamic catastrophe. Three cases involving prosthetic valve thrombosis are presented. Two patients suffered from thrombosis after tricuspid valve replacement (St. Jude Medical), while the third occurred after mitral valve replacement (Sorin). In the acute phase, systemic thrombolysis was initiated (2 MU Streptokinase during 22-28 hours). The obstruction of one of the tricuspid valves and the mitral valve was eliminated. Lysis of the other tricuspid valve was not complete, but it helped the patient to survive the acute phase until reoperation. Embolization occurred in the inferior extremity after thrombolysis of the mitral prosthetic valve, but it was cured. Two-dimensional and Doppler echocardiography (conventional and colour-coded) played an important role in the diagnosis of the obstruction and in the follow-up of the effectivity of thrombolysis. Systemic thrombolysis may be a lifesaving procedure in acute prosthetic valve thrombosis. In spite of the potentially dangerous complications, it has to be attempted.

Adult↗
PubMed1991

[Judging the severity of regurgitation in acquired heart defects using color-coded Doppler echocardiography].

In the study, 139 valvular regurgitations of 120 patients (55 mitral and 84 aortic regurgitations) were investigated and compared by means of colour flow mapping and heart catheterization. During the echocardiographic examination, the length and width of the regurgitant jets were measured and the jet area was planimetered besides the subjective grades. The above parameters were correlated with the angiographic grades. Good agreement was found between the results of the two methods. As concerns the different parameters of the regurgitant jets in mitral regurgitation, the most severe (grade IV) category was easily distinguished from the others, while in aortic regurgitation all four categories were differentiated by colour flow mapping. These measurements indicated that colour-coded Doppler echocardiography is a suitable tool for detection of the severity of valvular regurgitations in a noninvasive way.

Aortic Valve Insufficiency↗
PubMed1991

Comparison of topical fungicides in women suffering from vulvovaginitis.

The effects of Nizoral cream and clotrimazole ointment have been compared under identical experimental conditions in 35 resp. 37 women suffering from mycotic vulvovaginitis. Nizoral tablet was administered as a basic therapy. Significant differences were not observed when comparing the results of the different 10-day long adjuvant therapies. Considering therapeutic action Nizoral cream was found to be equivalent to the successfully used clotrimazole ointment.

Administration, Intravaginal↗
PubMed1991

Klion infusion for controlling surgical and other bacterial gynaecological febrile complications.

The incidence of febrile infectious postoperative complications following Caesarean sections and gynaecological major operations during 2 two-year periods has been retrospectively analysed. In the operated group receiving Klion infusion as an adjuvant to postoperative therapy infectious febrile complication occurred only in 2.63% of the cases versus the 6.73% of the control period without Klion therapy. The acute period of febrile acute pelvic inflammations decreased to 1-2 days in women treated with Klion infusion as well, versus the 3-4 days of the control cases. The study proved that prevention and therapy with metronidazole infusion decrease the incidence of complications and inflammations in which anaerobic pathogens play an important to about 50%.

Adult↗
PubMed1990

[Nondisplaced (impacted) femoral neck fracture--conservative or surgical treatment?].

The treatment of undisplaced femoral neck fractures, having been disputed for the past 50 years, is analysed on the basis of 111 observations during the period of 1981 to 1983. Osteosynthesis proved to be advantageous. Fixation with a three-flanged nail did not increase mortality rate, had no negative effect on late complications, while it could prevent dislocation and permitted full loading at an early stage.

Aged↗
PubMed1989

[Bladder repair using an ileocecal segment].

Subtotal cystectomy and bladder replacement from shorted-out ileocecal segment as well as uretero-ileostomy was carried out in a 25-year-old woman because of a contracted urinary bladder, consequence of a developmental disorder, i.e. colonic-type mucous membrane of the bladder. The patient is continent passes urine every 3-4 hours without residuum.

Adult↗
PubMed1989

Significance of urgent (within 6h) internal fixation in the management of fractures of the neck of the femur.

The value of internal fixation of fractures of the neck of the femur within 6 h was assessed in a review of a 3-year series. Three groups were compared, in which the operation was performed within 6 h, between 6 and 24 h and after 24 h respectively. The time and quality of union and the incidence of collapse of the head of the femur were significantly better in the first group. The difference in the results between the other two groups was not significant. In view of these data the authors recommend the internal fixation of fractures of the neck of the femur within 6 h.

Adolescent↗