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Biomedical subjects

A Verbuţă

Publications and source records attributed to A Verbuţă.

At least 19 recordsLinked to original sources
PubMedDate not supplied

[The evolution of lumbar myalgia under the influence of the product Pelnicol administered in suppositories].

After having done a wide study in vitro and in vivo reported in several publications, we applied the lyophylized extract "Pelnicol" under the form of suppositories, in 36 cases of secondary back diseases. The improvement with "Pelnicol" suppositories is observed, by mean, the 6th day of treatment. It can be seen that etiopathological factors are determining the diseases evolution, which has to be, in first rang, considered causally. It is realised with the "Pelnicol" suppositories.

Adult↗
PubMedDate not supplied

[Methodology for quality control of an ointment with antivaricose properties].

A personal formulation of an ointment with antivaricose properties is presented. A methodology for the physicochemical and rheologic control, including all parameters required by the standards for ointments quality control, was designed. The analyses showed that the ointment is stable in time, has a thixotropic consistency and behaviour and does not require special preservation conditions.

Chemical Phenomena↗
PubMedDate not supplied

[The quality assessment of a product with adhesive properties for complete dental prostheses].

A formula of dental adhesive using as an agent responsible for this activity an indigenous product, C.M.C.Na 1080, gelified with preservative solution with added astringent agents was elaborated. The possible interaction between the constituents during preservation and the product qualities by determining the pH, extensibility index, sliding limit tension, antimicrobial activity and certain clinical aspects were evaluated.

Adhesives↗
PubMedDate not supplied

The efficiency of some natural drugs in the treatment of burns.

In this paper we present an original product for burns. It is an ointment with bacteriostatic, bactericidal and epithelializing action and it is make up in accordance with technology of sunflower oil, beeswax, sintopholin, chloramphenicol, procaine, and vitamin E. An experimental study on burnt animals in order to prove the efficiency of the product was carried out. For histological investigation tegument was collected from the burnt area. A rapid evolution of epithelialization was found in case of treated animals as distinguished from control sample, where the infected crust was far from being healed. We also present some photos in account with the upper fact.

Animals↗
PubMedDate not supplied

[A study of pyramidone suppositories].

Our aim was to find a formulation for pyramidon suppositories in which the physicochemical compatibility of the active substance with the excipient to be the highest. Fatty and hydrosoluble excipients were studied. Following up in time the quality of the obtained preparation, it was concluded that the fatty substances are preferable, the suppositories with glycero-gelatinous mass being more stable by an one hour freezing and two hours freeze drying.

Antipyrine↗
PubMedDate not supplied

[The study of resorcin eyedrops].

Seven resorcin eye drop formulas using various physico-chemical stabilizers, acid buffer solutions, antioxidants such as sodium pyrosulphite, cysteine and keodants such as EDTA--Na were prepared. A parallelism between the physico-chemical stability and local biological tolerance in rabbit eyes was found, fact demonstrating that the occurrence of some oxidation products are responsible for the biological intolerance manifestations. A pH under 5 is favourable to resorcin stability and local biological tolerance to resorcin eye drops.

Animals↗
PubMedDate not supplied

[The production of tablets with diethylaminoethanol p-acetylaminobenzoate].

A formulation for tablets with diethylaminoethanol p-acetylaminobenzoate was set. The obtained tablets are adequate from the point of view of organoleptic qualities, mean weight weight variations, mechanical strength and disaggregation, both after processing and one year storage. The kinetics of water and artificial gastric juice, determined with the help of a Nogami device, by tablets capillarity reveals a homogeneous porosity, fact that determines the complete disintegration of the tablets in due time, and thus a good availability.

Absorption↗
PubMedDate not supplied

Epithelial mesenchymal interrelations at the skin level. A quantitative study.

Epithelial mesenchymal interrelations at the skin level were quantitatively studied by analysing the modifications of fibrocytes in the framework of total connective cells and capillaries of the dermic mesenchyme and of the number of mitoses in the epidermis. A normal group of guinea pigs was compared with a massaged one (II) and a massaged one using ointment (III). There were found significant differences between the elements of the first and those of the second and third groups, and no significant differences between the 2nd and the 3rd ones. There were established and compared the ratio of dermal fibrocytes to other connective cells, to dermal capillaries and to epidermal mitoses: the ratio remained similar in all groups. These results lead to the conclusion that dermis (expressed by its cells and capillaries) and epidermis (reflected in mitoses) have a correlated response to the mechanical action exerted in physiological limits, and that the epithelial mesenchymal dependence at the skin level is determined by the strong interrelations which are not easily modifiable.

Animals↗