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Biomedical subjects

A Violante

Publications and source records attributed to A Violante.

9 recordsLinked to original sources
PubMed1991

Normal serum biochemical and hematological parameters in Macaca fascicularis.

The effects of age, sex, pregnancy, were analyzed and data from fasted and fed animals were compared in a population of cynomolgus macaques. No significant sex effects were observed for biochemical values and no changes were found in male hematological parameters in relation to age. Most values of females during pregnancy were within normal ranges. Comparison between fed and fasted animals showed that several biochemical parameters (e.g., ALT, glucose, CPK, LDH) and several hematological parameters (e.g., monocytes, eosinophils, basophils, hemoglobin, MCV, MCHC, and MCH) were affected by food intake.

Age Factors↗
PubMed1990

Pituitary granuloma and pyoderma gangrenosum.

Pyoderma gangrenosum is a rare chronic and recurrent skin disease characterized by progressing lesions from papulopustules to large necrotic sterile ulcers. Its definite etiology remains unknown. In a 40-year-old woman with typical pyoderma gangrenosum an intrasellar mass with suprasellar extension was diagnosed and removed by transsphenoidal surgery. Histopathological features of the lesion were those of a nonspecific granulomatous hypophysitis. Five months postoperatively the patient experienced visual defects and hypopituitarism demonstrated by endocrine evaluation. Computerized tomography showed the recurrence of the intrasellar expanding mass. Extensive and repeated evaluation failed to find any evidence of sarcoidosis, tuberculosis or histiocytosis. Corticosteroid therapy was preferred to surgery and 80 mg daily prednisone produced a dramatic shrinkage of the pituitary pseudotumor. Long-term follow-up studies did not disclose any recurrence of the pituitary granulomatous process nor objective evidence of underlying disease even after steroid dosage has been tapered. The hypothesis of a pituitary localization of pyoderma gangrenosum is suggested by the similarity between the histopathologic findings of the two conditions and the excellent response to steroid therapy.

Adult↗
PubMed1990

[Relation between the production of deoxynivalenol and zearalenone and the mycelial growth of Fusarium graminearum on solid natural substrates].

A toxicogenic strain of Fusarium graminearum which produces DON and ZEA was cultivated on natural solid substrates (wheat, polished rice and hulled rice) under different environmental conditions. The production of both toxins and mycelium growth (in terms of glucosamine) were evaluated to establish the relation between the production of DON and ZEA and the different mycelium growth on the substrates mentioned above. Polished rice was the substrate on which most production of both toxins was obtained. Comparing the three substrates studied, the highest quantities of DON were obtained at a temperature of 27 degrees C during incubation period, being indifferent to the presence of light except in the case of hulled rice. Whereas for ZEA the best conditions in wheat and polished rice were medium temperatures (17 degrees-21 degrees C respectively) and darkness. While in hulled rice the ideal conditions for the production of both toxins were temperature of 27 degrees C and the presence of light. Concerning the mycelium growth, this was very scarce when cultivated in hulled rice, increasing in polished rice and being largest in wheat. The increase or reduction of the mycelium growth in the different substrates was not proportional to the increase or decrease of the production of both toxins. Therefore, production of DON and ZEA could be subjected to the nature of the substrate and environmental conditions, more than the rate of development of Fusarium graminearum in cereal grains.

Food Microbiology↗
PubMedDate not supplied

[Antileukocyte antibodies. Synthetic review and experimental data].

An account is given about the results of investigations carried out in repeatedly transfused patients. We observed an increased presence of the antileucocyte antibodies in relation to the repeatedly transfused patients. The work was extended also to the repeatedly pregnancies; in this research it was also observed a sensibly increased presence of the antileucocyte antibodies in relation with the number of the pregnancies.

Agglutination Tests↗
PubMedDate not supplied

[Laboratory tests applied to transfusion problems. Identification of dangerous universal donors and their frequency].

We studied 504 subjects, whose blood group wes O; they were periodic or occasional blood donors from Transfusional Center A.V.I.S., Policlinico "Umberto I", Roma. Our research was based on the principle stated by Gandini: he states that the natural isoagglutinin concentration equal or superior to 1:200 and the presence of hemolytic isoantibodies may make universal donors dangerous. Our results indicated that the percentage of this kind of donors is 27.75%. Sice 17.26% of our studied subjects showed hemolytic antibodies, we consider it is sufficient to identify dangerous donors through a dosage of hemolytic isoantibodies.

Blood Donors↗