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Biomedical subjects

A W Eller

Publications and source records attributed to A W Eller.

31 records · Page 2Linked to original sources
PubMed1990

Serous retinal detachment resembling central serous chorioretinopathy following organ transplantation.

Two patients developed unilateral serous retinal detachments of the macula resembling idiopathic center serous chorioretinopathy within 9 months of cardiac transplantation, while one renal transplant recipient developed bilateral serous detachments within 6 months of surgery. In two cases (three eyes), dense, yellow, fibrlin-like exudates were present in the subretinal fluid. At the time of presentation, each of the three patients had a modest elevation of blood urea nitrogen. Laser photocoagulation was performed in three eyes with limited success, although ultimately the detachments resolved leaving only mild visual impairment (6/9 vision). The differential diagnosis of visual loss in the transplant population includes serous detachment of the sensory retina as well as more serious chorioretinal infections related to immunosuppression.

Choroid Diseases↗
PubMed1988

Pneumatic repair of primary and secondary retinal detachments using a binocular indirect ophthalmoscope laser delivery system.

Using intravitreal gas injection of sulfur hexafluoride after retinopexy utilizing a binocular indirect ophthalmoscope argon laser delivery system, the authors treated 12 primary rhegmatogenous retinal detachments and 10 detachments which recurred after previous scleral buckle surgery. Topical anesthesia only was used in most of the cases (18 of 22). Detachments in all quadrants of the fundus were repaired. Twenty cases remained successfully attached after a minimum follow-up of 6 months. Two failures occurred early in eyes with primary retinal detachments and both were successfully repaired by conventional scleral buckling techniques. The authors found pneumatic retinal reattachment in conjunction with laser retinopexy to be particularly valuable in repairing secondary detachments, thereby avoiding conventional surgical reoperations.

Cryosurgery↗
PubMed1987

Use of directly acquired digital fundus and fluorescein angiographic images in the diagnosis of retinal disease.

Direct on-line acquisition of digital fundus and fluorescein images is a useful alternative to conventional fundus photography. Immediately after acquisition, digital images may be electronically reassembled, manipulated, and displayed, avoiding the delays inherent in film development. Digital fundus images, conventional photographs, and fluorescein angiograms were obtained at the same sitting in 50 consecutive patients with retinal disease. Digital studies were displayed on a video monitor and diagnoses were made directly from the screen. The interpretations based on digital images alone were virtually identical to those made from photographs, although the resolution of digital images was not equal to that of the photographic images. Despite this disadvantage, the system proved extremely versatile, and for this reason, digital image acquisition was used to routinely document the retinal findings in the majority of the clinical patients.

Fluorescein Angiography↗
PubMed1987

Retinopathy of prematurity. The association of a persistent hyaloid artery.

In a review of 160 cases of retinopathy of prematurity (ROP), 14 patients were found to have an associated persistent hyaloid vascular system. The following four different manifestations of a persistent hyaloid system were identified: hyaloid artery anastomosed to peripheral neovascularization (1 case); hyaloid artery present with attached retina (3 cases); fibrous-appearing stalk with detached retina (3 cases); and massive persistent hyaloid vascular system (7 cases). In some cases, the hyaloid artery was only an associated finding and unrelated to ROP. In other cases, the hyaloid artery appeared to be an integral component of the retrolental membrane. Recognition of a massive persistent hyaloid artery has important prognostic value because the vessels are adherent to the retina and the retrolental membrane complicating surgical repair. The role of the associated hyaloid artery in ROP is described.

Humans↗
PubMed1985

In situ actin distribution in excised retrolental membranes in retinopathy of prematurity.

Actin, an intracellular contractile protein, is associated with cell movements in both muscle and nonmuscle tissues. Using the fluorescent derivative of the mushroom toxin, phallacidin, which specifically binds to polymerized (filamentous) actin, we demonstrated the distribution of actin in retrolental membranes excised during open-sky vitrectomy from six infants with leukokoria due to retrolental fibroplasia. Actin was detected in ubiquitous linear bundles, which is consistent with the existence of contractile forces. Actin was also concentrated in the cortical cytoplasm of cells, thus outlining the plasma membranes. Transmission electron microscopy has identified many of these cells to be myofibroblastlike in appearance. Myofibroblasts are known to contract like smooth-muscle cells and have been reported as the putative causal factor in the contraction of scars and transvitreal membranes.

Actins↗
PubMed1983

Retinal disorders of childhood.

Included in this discussion of retinal disorders affecting infants and children are retrolental fibroplasia, diabetic retinopathy, sickle cell retinopathy, retinal detachment, retinal hemorrhages of neonates, macular disease, colobomas, ocular toxocariasis, and TORCH syndrome.

Anemia, Sickle Cell↗
PubMed1983

Blue nevi of the conjunctiva.

Two examples of conjunctival blue nevi are presented. The clinical and histologic features of these lesions are not in accord with descriptions of blue nevi in the ophthalmic literature. In both cases, the nevi's clinical appearance was brown instead of blue; the nevi could be moved with the conjunctiva over the sclera; and they were not present at birth. Histologically, they demonstrated subepithelial, spindle-shaped melanocytes. The location of the cells was no deeper than that of common acquired compound or subepithelial conjunctival nevi.

Adult↗
PubMed1983

Quantitated trauma following radial keratotomy in rabbits.

Radial keratotomy was performed in 33 rabbits using an eight-incision technique. At various postoperative intervals up to 90 days, these eyes were enucleated and subjected to increasing quantitated trauma until ocular rupture occurred. Control animals (13 eyes) were subjected to similar trauma. The eyes that had surgery required approximately 50% of the control energy to rupture over the 90-day period (P less than 0.001). Corneal microperforations at surgery greatly increased the trauma risk (P = 0.02). Consistent rupture patterns resulted, both grossly and microscopically.

Animals↗
PubMed1980

Melanocytoma of the ciliary body and iris.

A 29-year-old woman had a pigmented ciliary body mass that extended through the iris into the anterior chamber. On the basis of clinical findings and ancillary diagnostic studies, the clinical diagnosis was malignant melanoma of the ciliary body. The enucleated eye showed the tumor to be composed of cells identical to those of a melanocytoma of the optic disk.

Adult↗
PubMedDate not supplied

Subretinal neovascularization in children and adolescents.

Subretinal neovascular membranes (SRNVM) in the pediatric population are rare. The clinical presentation, etiology, course, and management of SRNVM in 25 children (27 eyes) were studied retrospectively. Inflammatory or infectious conditions predominated (10 of 25). Eleven of 19 untreated SRNVM (58%) spontaneously involuted, with 9 of these 11 achieving a final visual acuity of 20/50 or better. A hyperpigmented ring on fluorescein angiography was associated with 9 of the 11 involuted SRNVM. The presence of this pigmented ring may help to identify those cases with a better visual prognosis.

Adolescent↗
PubMedDate not supplied

Laser pneumatic retinopexy for repair of recurrent retinal detachment after failed scleral buckle--ten years experience.

BACKGROUND: Although pneumatic retinopexy was introduced for the repair of primary retinal detachments, we have had excellent long-term success in employing this technique along with laser photocoagulation following failure of routine scleral buckle surgery in nonvitrectomized eyes over the last 10 years. PATIENTS AND METHODS: We categorized a consecutive series of 40 eyes that failed primary scleral buckling surgery and had at least six months follow-up. Eyes were separated into two groups: those with 1) subretinal fluid persisting or developing during the first 14 days after surgery or 2) those accumulating subretinal fluid at least 14 days after initially successful anatomic reattachment of the retina. RESULTS: In these groups, 36 of the 40 eyes (90%) were successfully reattached using outpatient pneumatic retinopexy alone. Complications were limited to the production of new retinal breaks in 5 patients. The 4 pneumatic retinopexy failures were all subsequently treated successfully with either scleral buckle revision or vitrectomy. CONCLUSION: We believe that laser pneumatic retinopexy repair of recurrent retinal detachments following scleral buckle and without significant proliferation vitreoretinopathy (PVR) should be considered ahead of conventional surgical intraoperative techniques. Laser pneumatic retinopexy may be a very successful procedure for the treatment of recurrent retinal detachments after failed scleral buckle surgery. In a consecutive series of 40 eyes with recurrent retinal detachment, we were able to repair 36 with pneumatic retinopexy alone.

Adolescent↗