PubMed Health⌕ Search

Biomedical subjects

A W Eriksson

Publications and source records attributed to A W Eriksson.

At least 127 records · Page 7Linked to original sources

alpha1-antitrypsin: common subtypes of Pi M.

More than 20 different alleles are so far known at the Pi locus, corresponding to a total variant phenotype frequency of about 10% in most western Europeans. The common phenotype Pi M constitutes the remaining major group. Now it has been possible to identify three subtypes M1, M1M2 and M2, corresponding to the gene products of two common alleles PiM1 and PiM2, segregating as autosomal codominant alleles. Preliminary gene frequencies are reported for eight populations, the PiM2 frequency varying from 0.20 in Maris (USSR) to 0.02 in Bantus (Kenya).

Alleles↗

Blood pressure in adult Lapps and Skolts.

Casual blood pressures were recorded in 331 Lapps and 221 Skolts over the age of 20. The systolic pressure was found to rise more with age in women than in men. In neither sex did age affect the diastolic pressure. A general tendency towards higher blood pressure in Lapps than in Skolts was noted up to the age of 50-60 years. Comparison with a Finnish population and one from the Aland Islands revealed similar systolic blood pressures in females, but definitely lower values in male Lapps and Skolts. The Lapps and Skolts did not have the clear age dependence of the diastolic blood pressure as occurs in Finns. These findings, together with other population studies, support the hypothesis that the setting of the resting blood pressure level is influenced by different kinds of stress associated with technological development and with an urbanized way of life.

Adult↗