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Biomedical subjects

A W Macleod

Publications and source records attributed to A W Macleod.

8 recordsLinked to original sources

Cat-scratch disease: a case report.

Cat-scratch disease is the most common cause of benign lymphadenopathy in children and young adults. A 21-year-old patient presented with a 14-day history of asymptomatic left submental swelling. Clinical and radiographic examination revealed no dental cause. An enlarged, firm nodule was excised. The histopathologic appearance was consistent with cat-scratch disease. This article summarizes the relevant literature and discusses diagnosis and treatment of cat-scratch disease.

Adult↗

An infected mandibular fracture. Case report.

A case of an infected mandibular fracture is presented. A submandibular abscess appeared to arise from chronic pericoronal infection associated with a third molar tooth in the line of fracture. Treatment of the case is described followed by a short discussion on the aetiology and management of infected mandibular fractures. The importance of adequate first aid and prompt referral is stressed.

Abscess↗

The effects of diflunisal on bleeding time and platelet aggregation in a multidose study.

Diflunisal, a potent nonsteroidal anti-inflammatory agent, has been confirmed as an effective analgesic in oral surgery. It is generally stated that there is only slight impairment of coagulation at the recommended dosage of diflunisal; however, only a few multidose studies have been conducted, most being single dose studies. This report is of a multidose study of the effects of diflunisal on coagulation in 15 oral surgery patients, being the first such study reported. The results showed that the bleeding time was increased in 53% of the group, but in no case did the increase exceed the upper limit of normal. Additionally, platelet aggregation studies were affected in 38% of patients with increased bleeding time. The overall results substantiate the safety of diflunisal in relation to effect on coagulation, and are directly applicable to postoperative use in oral surgery.

Adolescent↗

A clinical study of bupivacaine for mandibular anesthesia in oral surgery.

Previous studies have shown the usefulness of bupivacaine in oral surgery. A clinical trial was conducted comparing bupivacaine to lidocaine in 20 patients undergoing the surgical removal of bilateral impacted mandibular third molar teeth at separate appointments. A combination analog and category pain scale was used to assess pain on four occasions over the first 24 hours following the operation. Results showed a marked reduction in postoperative pain experienced over this time and almost unanimous patient preference for bupivacaine.

Adolescent↗