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Biomedical subjects

A W Pengelly

Publications and source records attributed to A W Pengelly.

10 recordsLinked to original sources
PubMed1999

The role of urine cytology in the assessment of lower urinary tract symptoms.

OBJECTIVE: To evaluate the role of urine cytology in the investigation of men with lower urinary tract symptoms (LUTS) in the absence of haematuria. PATIENTS AND METHODS: The study comprised 336 men attending a LUTS assessment clinic, who had neither macroscopic nor microscopic haematuria. One sample of urine was collected for cytology. Those with suspicious urine cytology were investigated with intravenous urography and cystoscopy. RESULTS: Five men had abnormal urine cytology results; on further investigation one of them was found to have carcinoma in situ (CIS) and one to have a transitional cell carcinoma. Three had false-positive urine cytology results. CONCLUSION: A bladder tumour or CIS was detected in 0.6% of the population tested. The cost per cancer diagnosed was GB pound 2020. Urine cytology is a simple noninvasive way of assisting accurate diagnosis of men who have LUTS in the absence of haematuria.

Carcinoma in Situ↗
PubMed1993

The mobile lithotriptor: an answer for the smaller centre.

The mobile lithotriptor is a new method of providing extracorporeal shock wave lithotripsy (ESWL) directly to the smaller urological centres. The unit, containing a Dornier HM4 lithotriptor, has treated 135 patients with a total of 168 treatments in 2 centres in the Oxford region. The overall success rate was 87% with no serious morbidity or mortality. The results compare well with the results from larger centres and the system is cost-effective. We suggest that it is one of the best methods of providing ESWL to the smaller urological centres.

Adolescent↗
PubMed1988

Oxybutynin: is it safe?

Oxybutynin has been widely prescribed in the United Kingdom for more than 5 years on a named patient basis. Complete knowledge of its side effects is therefore particularly important. The literature contains remarkably little data on this topic. We therefore reviewed 192 consecutive patients for whom the drug had been prescribed in a district general hospital; 57% derived benefit while 76% noted side effects, none of which was dangerous or irreversible. Oxybutynin obtained from the two principal suppliers did not appear to differ either in efficacy or side effects. We discuss the uncertain medicolegal implications of named patient prescriptions.

Adolescent↗
PubMed1980

A prospective trial of bladder training as treatment for detrusor instability.

Bladder training, without the additional use of drugs, has been used as treatment for detrusor instability. In a 3-month prospective trial, with historical controls, nearly half of the treated patients were either cured or improved. Bladder training is, therefore, a successful non-invasive technique devoid of complications and is recommended for the treatment of mild detrusor instability.

Adolescent↗
PubMed1979

The intravenous urodynamogram.

Modifications to the intravenous urogram are described. It is suggested that the time has come to rationalise the standard procedure. If an evaluation of the lower urinary tract is required, the voiding films may be modified to provide an intranvenous urodynamogram. If an evaluation of the upper urinary tract is directed at a specific question, then the number of spot-films can often be reduced.

Adult↗
PubMed1978

Results of prolonged bladder distension as treatment for detrusor instability.

Forty-six patients with urinary symptoms associated with unstable (uninhibitable) detrusor contractions have been treated by a total of 58 bladder distensions; 43 of these were fully re-evaluated urodynamically thereafter and none showed conversion from unstable to stable detrusor behaviour. Four patients with unstable bladders were symptomatically improved but 5 patients reported symptomatic deterioration. We have concluded that while over-distension may sometimes improve a patient's symptoms, it did not result in the abolition of detrusor contractions or the reversal of unstable detrusor behaviour.

Adolescent↗