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Biomedical subjects

A W Samuel

Publications and source records attributed to A W Samuel.

15 recordsLinked to original sources
PubMed1993

Functional outcome after intertrochanteric fractures of the femur: does the implant matter? A prospective study of 100 consecutive cases.

In a randomized study of 100 consecutive patients with an intertrochanteric fracture of the femur fixed internally either with a sliding hip screw or with a McLaughlin nail-plate, the functional outcome of the 6 months survivors has been analysed. There was no statistically significant difference between the two treatment groups with regard to the rehabilitation progress and recovery to the prefracture walking ability, pain and gait at 6 months. Of the 6 months survivors, 55 per cent whose fractures were unstable and 76 per cent whose fractures were stable regained 90 per cent or more of their individual prefracture walking ability. The incidence of failure by 'cutting-out', the reoperation rate and the mortality at 6 months were not statistically different in the two treatment groups.

Bone Nails↗
PubMed1987

A prospective study of parachute injuries in civilians.

A prospective study of 33 civilian parachutists with 41 injuries is presented. Because the training for civilians is less rigorous than that for military parachutists, the hospital admission rate for severe injuries was high (81.8%). Most injuries occurred during landing and the ankle was most frequently involved. The types and possible mechanisms of injury are discussed, as well as recommendations for modifying the civilian training programme.

Adolescent↗
PubMed1985

Isolated Dislocation of carpal scaphoid.

The functional role of the scaphoid in stabilising the wrist joint is discussed and the literature on scaphoid dislocations reviewed. A case of isolated dislocation of the scaphoid has been presented with the salient diagnostic features and preferred line of management which includes percutaneous Kirschner-wire fixation to ensure maintenance of the reduction.

Accidents, Occupational↗
PubMed1982

Primitive neuroectodermal tumor arising in the ulnar nerve. A case report.

Malignant peripheral nerve tumors are rare. A neuroectodermal tumor arose in a 59-year-old man from the ulnar nerve. Typically, the tumor reproduces some of the appearances of cells of the primitive central nervous system. The possibility that a primary tumor of the sympathetic nervous system, especially of the adrenal glands, should be considered in the differential diagnosis. The tumor may arise from a major peripheral nerve and show features of growth patterns of the embryonic central nervous system. Blood stream spread is not uncommon; awareness of this proclivity makes early diagnosis mandatory.

Humans↗
PubMed1981

The Larsen syndrome with multiple congenital dislocations and a normal facies.

Details of four children with congenital skeletal abnormalities are reported. In one, typical of the Larsen Syndrome, and autosomal dominant pattern of inheritance is demonstrated. The three others show marked skeletal abnormalities similar to those seen in the Larsen Syndrome but without the usual characteristic facial features.

Abnormalities, Multiple↗
PubMed1980

The effect of prostaglandin synthesis inhibitors and diphosphonates on tumour-mediated osteolysis.

Previous studies have shown that the prostaglandin synthesis inhibitor indomethacin reduced osteolysis produced by the experimental VX2 carcinoma, probably by inhibiting the stimulation of osteoclasts by prostaglandin E2. This study was carried out to determine whether prostaglandin inhibitors affect the tumour osteolysis produced by human mammary carcinoma as well as the VX2 carcinoma. The effect of diphosphonates on reducing tumour osteolysis was also investigated, since diphosphonates directly affect bone resorption. The results indicated that various non-steroidal, anti-inflammatory agents which inhibit prostaglandin synthesis reduced the osteolysis produced by human mammary or rabbit VX2 carcinomas. The diphosphonate compounds also produced a significant inhibition of tumour osteolysis. The results confirm the findings of Powles and his colleagues (1) that aspirin (also a prostaglandin synthesis inhibitor) reduced the osteolysis induced by human mammary carcinoma. It is suggested that these agents be evaluated as adjuvant therapy in patients with apparently 'early' mammary cancer in a controlled clinical trial.

Animals↗
PubMed1977

A review of malingering and hysteria in clinical practice.

Hysteria and malingering, both commonly seen, especially in orthopaedic clinics, are reveiwed. Advances in psychology and psychiatry are often unknown or ignored by surgeons, who may thus mistreat or misdiagnose a multitude of conditions.

Diagnosis, Differential↗