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Biomedical subjects

A Walsted

Publications and source records attributed to A Walsted.

5 recordsLinked to original sources

Hearing decrease after loss of cerebrospinal fluid. A new hydrops model?

In a prospective study of 12 patients undergoing operation for acoustic neuromas the hearing on the contralateral ear was tested before and systematically day by day after operation. In 11 cases a perceptive loss of at least 20 dB was found at one or more frequencies during the first 2 postoperative weeks. A maximal average threshold decrease of 16.5 dB was found in the treble (2.4, 8 kHz average), while a tendency of a more pronounced decrease of 19.6 dB was seen in the low frequencies (125, 250, 500 Hz average). After 3 months the hearing had normalized in all cases. The explanation for the transitional loss supports the present theory: The loss of cerebro-spinal fluid during operation diminishes the CSF pressure. This decrease is transmitted to the perilymph via the cochlear aqueduct producing a transitory perilymphatic hypotonia, which in turn hydromechanically results in a relative endolymphatic hypertension mimicking an endolymphatic hydrops thus representing a human hydrops model.

Adult

Low-frequency hearing loss after spinal anesthesia. Perilymphatic hypotonia?

Audiological tests were conducted on 34 patients before and after undergoing an operation under spinal anesthesia. One of these patients developed a considerable unilateral hearing loss in the low-frequency range, which persisted until an epidural blood-patch was given. Unexpectedly, we also found a general small significant threshold shift at 500 Hz, which has never before been described in the literature. The biological mechanism is discussed and the results suggest that the explanation of the hearing loss could be an endolymphatic hydrops resulting from perilymphatic hypotonia due to loss of liquor, during and after the spinal anesthesia.

Adult

[Surgical treatment of chronic maxillary sinusitis. Report of a new surgical technic and an evaluation of results of traditional surgery].

During recent years, a new operative procedure for treatment of chronic maxillary sinusitis has been strongly recommended as being more effective and more physiological than the traditional Caldwell-Luc operation. The principle of the method is endoscopically guided endonasal resection of the anterior ethmoid cells and enlargement of the natural ostium of the maxillary sinus in the middle meatus. In contrast, the principle in the Caldwell-Luc operation is opening into the sinus in the canine fossa, providing direct approach to the lumen, and finally creation of a fenester towards the inferior meatus. However, the publications hitherto presented have not documented clearly the efficiency of this new method, which also appears to have an increased risk of complications, some of which are serious. The present study elucidates the efficiency and side effects of the traditional Caldwell-Luc operation in 77 patients (107 maxillary sinuses). Four to nine years after the operation 73% of the patients had had satisfactory subjective effect of the operation. Consistency was present between the subjective estimation and the objective findings at follow-up. The effects included only slight disturbances of the sensibility in the infraorbital nerve (n = 9) or teeth (n = 6). However, only two patients (3%) had more troublesome change of the sensibility in the infraorbital nerve and in one patient only a subjectively "dead" tooth was also avital at vitality testing. The survival of the teeth was estimated roughly by comparison of the number of teeth on the operated side versus the non-operated side and was unimpaired.(ABSTRACT TRUNCATED AT 250 WORDS)

Adolescent

Two malignant melanomas in skin and tonsil during consecutive pregnancies.

A patient is described with two primary malignant melanomas which developed during consecutive pregnancies four years apart. The first melanoma was of the cutaneous nodular type located on the arm. The second, of the superficial spreading type, was located in the oral mucosa near the right tonsil. The influence of pregnancy on the development and outcome of malignant melanomas is discussed, and the risk of a subsequent pregnancy is emphasised.

Adult