[Allergotoxic brain reaction to flupentixol-depot].
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Biomedical subjects
Publications and source records attributed to A Wasik.
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Control CT assessments of the brain of 15 alcohol dependent patients who showed an improvement in their clinical state were performed after a mean of 16 months. A partial decrease of the widening of cerebral sulci and the third ventrical was noticed. Also, the neuroradiological pictures of the vermis and cerebellum were seen to improve in most patients.
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In the group of 35 in-patients (30 female, 5 male) from the Department of Psychiatry, Medical Academy in Wrocław with depression resistant to antidepressive pharmacotherapy, the evaluation of ES therapy was made. The high efficacy (63% of full remissions) showed combined ES therapy with tricyclic antidepressants; only in 2 female and in 1 male patient there was no effect. At the same time neither serious side-effects nor complications were found, even in older patients.
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In order to examine the circulatory and bronchospasmolytic activity, new 7-beta-hydroxy-gamma-N4-alkylpiperazinopropyl-8- benzylaminotheophyllines (1, 2, 3) were synthesized and converted to the water soluble dihydrochlorides (1a, 2a, 3a). They showed hypotensive and bronchodilatory effect.
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