[False positives in breast pathology].
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Biomedical subjects
Publications and source records attributed to A Willemin.
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Malignant tumor in the breast create a stroma-reaction that gives the typical aspect of malignant picture with retractile fibrosis, oedema and microcalcifications (10 to 15%). The diagnosis is really uncertain in only 2% of the cases. Cytology after fine needle puncture permit the diagnosis.
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The discovery of carcinomatous cells in a discharge from a breast, without any other clinical, mammographic or thermographic sign, allowed the removal of a carcinoma in its pre-clinical stage. The histological study in a series of cuts showed a carcinoma that was still intraductal and which showed signs of cellular regression accompanied by marked peri-canalicular sclerosis associated with inflammatory infiltration. This observation allows commentaries to be made concerning the immunological process that goes with carcinoma in its intra-epithelial stage and permits the possibility of predicting an advance in the understanding and treatment of carcinomata which should be diagnosed very early.