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Biomedical subjects

A Y Hoshino

Publications and source records attributed to A Y Hoshino.

7 recordsLinked to original sources

The effect of work shift on nurses' evaluations of patient behavior: implications for team decision making.

The authors conceptualized multidisciplinary team decision making in terms of information collection, communication, and combination. The study explored the potentially biasing effects of situational variables on information collection. When compared with evening shift nurses, day shift nurses rated patients as much less competent. The authors discuss how this biased information collection can be transmitted throughout the decision process and suggest that more attention be paid to situational influences on information used in team decision making.

Attitude of Health Personnel↗

Serum glycoproteins in schizophrenia.

A comparative investigation of the individual protein-bound carbohydrate components and the distribution of carbohydrates in the electrophoretic glycoprotein fractions was carried out in sera from 20 normal subjects and 30 schizophrenic patients matched for age and sex. The mean concentration of each of the protein-bound carbohydrate components was significantly elevated in schizophrenics. The electrophoretic patterns for serum glycoprotein showed increases in alpha-2 and beta globulins in schizophrenics. The serum glycoproteins contained glucose and L-arabinose, in addition to mannose, galactose, fucose, sialic acid, and a trace of xylose. The identity of glucose and arabinose was confirmed by g.l.c.-electron-impact mass spectrometry and by specific enzymic reactions. The contents of glucose and arabinose were higher in serum glycoproteins from schizophrenic patients. This elevation of serum glycoprotein paralleled serum glycosaminoglycan elevation previously reported by us, but was opposite to decrease of urinary glycoprotein in schizophrenics.

Carbohydrates↗

Simple gas-chromatographic measurement of valproic acid in psychiatric patients: effect on levels of other simultaneously administered anticonvulsants.

A simple, rapid and precise gas-chromatographic procedure which involves one-step extraction and on-column methylation for routine clinical monitoring of plasma valproic acid levels is described. Six other commonly, simultaneously administered anticonvulsants can also be determined by substituting methylene chloride for chloroform for extraction and changing the column temperature. Also, described is the effect of valproic acid on blood levels of other simultaneously administered anticonvulsants.

Adult↗

Serum and mucopolysaccharide (glycosaminoglycans) levels in psychiatric patients.

Serum acid glycosaminoglycans (GAG) levels were measured in 50 normals and 177 samples from different types of psychiatric patients. Mean levels were significantly higher in paranoid type schizophrenia, organic brain syndrome associated psychosis and manic type manic-depressive psychosis. The levels returned to slightly above the normal range upon partial remission in paranoid schizophrenics. In catatonic and hebephrenic schizophrenias the values were in the upper part of normal range. The levels were either in upper normal range or slightly higher in non-psychotic organic brain syndrome. In depressed type manic depressive psychosis levels were either lower than normal or in the lower part of normal range.

Adolescent↗

Therapy for deliria.

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Alcohol Withdrawal Delirium↗