Bactericidal index in burns.
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Blood Bactericidal Activity↗
Biomedical subjects
A Y Sukhtankar
Publications and source records attributed to A Y Sukhtankar.
Cellular immunity in burns.
Evaluation of cellular immunity in burns was undertaken using the following parameters: T-cell count; blastoid transformation and macrophage migration inhibition factor index (MIF). Their influence upon bactericidal index was also measured as T-cell count per mm3 and in percentage was found to be depressed in parallel, probably due to some cellular immune in parallel, probably due to some cellular immune functions active at the burned site. Blastoid transformation and MIF index were found to be depressed in parallel especially in major burns, i.e. above 25 per cent. These parameters had a significant influence upon the bactericidal index thus enhancing its activity to a considerable extent when values of the former were approaching near normal limits.
Burns↗
Humoral immunity in burns.
Evaluation of serum immunoglobulin levels for IgG, IgA and IgM in burned patients was performed by Johanson's modification of Mancini's technique. Influence of serum immunoglobulin levels upon the bactericidal capacities was also measured. Levels of all three immunoglobulins were found to be affected in burned individuals compared with healthy control group. For burns below 25 per cent, immunoglobulin G showed two troughs on the third and seventh days post burn, signifying mechanical depletion and possibly loss in opsonic activities respectively; immunoglobulin A was found persistently below normal limits signifying possibly major loss in opsonic activities; immunoglobulin M showed only an occasional fall signifying minimal loss. The role of immunoglobulins in enhancing the bactericidal index was also made very clear in the present study.
Antibody Formation↗