[Tuberculosis of bronchi and lymph nodes mimicking cancer in a patient with HIV-infection].
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AIDS-Related Opportunistic Infections↗
Biomedical subjects
A Yapi
Publications and source records attributed to A Yapi.
[Characteristics and evolutive data of chronic respiratory diseases after respiratory intensive care. Evaluation of the Pneumology Department of the Pavillon Saint-François in Strasbourg between 1980 and 1985].
Between 1980 and 1985, 66 patients with chronic obstructive lung disease (respiratory deficit of the restrictive type) were admitted to our department after an episode of acute respiratory failure treated with assisted ventilation in an intensive care unit. These patients were in a particularly poor clinical condition, due to their previous long stay in the intensive care unit (mean 43 days), the high percentage of tracheotomies (mean 44%), the loss of autonomy of movement in 30% of the cases and the presence of an associated pathology in 45% of the patients. These data explain the high mortality observed in this group: 40% of the patients died within one year of the acute respiratory failure episode. Other prognostic factors, notably the patients' nutritional status, must also be taken into account.
Aged↗
Species-specific field testing of Entamoeba spp. in an area of high endemicity.
Entamoeba histolytica has been separated in recent years into 2 morphologically identical species: the apathogenic E. dispar and the pathogenic E. histolytica, only the latter being pathogenic. Although various laboratory techniques allow discrimination between the 2 species there is a lack of field data about the suitability of available diagnostic tests for use in epidemiological studies and few epidemiological studies using species-specific diagnosis have been performed at community level in endemic areas, especially in sub-Saharan Africa. We conducted a repeated cross-sectional study of 967 schoolchildren in central Côte d'Ivoire to compare and evaluate light microscopy, 2 different antigen detection assays, and one polymerase chain reaction (PCR) assay. Microscopy and a non-specific antigen capture Entamoeba enzyme-linked immunosorbent assay (ELISA) were used for the primary screening of all children (time t0). The prevalence of the E. histolytica/E. dispar species complex at t0 was 18.8% by single microscopical examination and 31.4% using the non-specific ELISA. Approximately 2 months after the initial screening, fresh stool specimens were collected on 2 consecutive days (t1 and t2) from (i) all the children who were positive by microscopy at t0 (n = 182) and (ii) 155 randomly selected children who were negative at the primary screening. These samples were tested with a second antigen detection ELISA specific for E. histolytica (n = 238) and with a species-specific PCR assay (n = 193). The second and third examinations (t1 and t2) revealed an additional 43 infections with the species complex E. histolytica/E. dispar, so that the cumulative microscopical prevalence for t1 and t2 was 27.7%. The overall prevalence of E. histolytica by species-specific ELISA antigen detection was low (0.83%), while the prevalence of E. dispar was 15%. When analysing only microscopically positive samples by PCR (n = 129), the ratio E. histolytica: E. dispar was very low (1:46), suggesting that the vast majority of Entamoeba infections in this area were apathogenic. Both species-specific tests performed well but the ELISA was easier to use for large-scale field screening.
Adolescent↗
[Acute bacterial pneumonia in retroviral infections. Epidemiologic, clinical, radiologic, bacterial and developmental aspects].
From a prospective study starting January 8 to 1990 October 20, the authors discuss 70 cases of acute pneumopathy, supposed to be bacteriologic in patients infected by HIV. The observed pneumopathies are more frequent in young adults, with a pic between 20 to 40 (67.15 p.c). The positivity rate of hemocultures was estimated at 17.14 p.c. with a clear predominance of non typhic Salmonellae. The evolution observed, generally favourable at 72.85 p.c was fatal in 17.15 p.c.
Adult↗