Biomedical subjects

A Yiğit

Publications and source records attributed to A Yiğit.

6 recordsLinked to original sources

PubMed2001

Wernicke's encephalopathy due to hyperemesis gravidarum: an under-recognised condition.

We present a case of a 25-year-old woman with drowsiness, nystagmus, severe ataxia and areflexia, which developed six weeks after admission to an obstetric clinic for hyperemesis gravidarum. She had been treated with intravenous dextrose and electrolyte solutions and antiemetics. Magnetic resonance imaging (MRI) performed on the fifth day of her neurologic symptoms showed increased intensity in both thalami, periaqueductal grey matter, the floor of the fourth ventricle and superior cerebellar vermis in T2 weighted and FLAIR images. Clinical signs and MRI findings were consistent with the diagnosis of Wernicke's encephalopathy. On the third day of thiamine replacement, neurologic signs improved dramatically In addition to our case, we review 29 previously reported cases of Wernicke's encephalopathy associated with hyperemesis gravidarum, and emphasize the importance of thiamine supplementation to women with prolonged vomiting in pregnancy especially if they are given intravenous or parenteral nutrition.

Adult↗

PubMed2001

Effect of sodium valproate on somatosensory evoked potentials in juvenile myoclonic epilepsy.

We analysed somatosensory evoked potentials (SEPs) in the patients with juvenile myoclonic epilepsy (JME) in order to find out if sodium valproate (VPA) affects SEP latencies and amplitudes. SEPs were studied in 23 patients with JME receiving VPA monotherapy, eight patients with JME not receiving VPA, and a control group consisting of 20 healthy subjects. The N20, P24, and N34 latencies bilaterally were significantly prolonged in the JME group receiving VPA as compared with the control group. In the untreated patients the P24, and N34 latencies bilaterally and the N20-P24 interpeak latency on the right, were significantly prolonged as compared with the control group. In addition, in the patient group without treatment, the N20-P24 amplitudes bilaterally and the P24-N34 amplitudes from left sided median nerve stimulation, were greater as compared with the control group. In the SEP latencies, no significant differences were observed between the patients treated and untreated with VPA. Regarding SEP amplitudes, in the untreated group, while the N20-P24 amplitudes from right sided median nerve stimulation were significantly enhanced, all the other amplitudes also showed increase, even insignificant, as compared with the patients treated by VPA. These findings suggest that the SEPs latencies are prolonged, and the amplitudes are enhanced in JME. The changes of the SEPs latency in JME could be due to abnormal synaptic transmission and not influenced by VPA. On the other hand, the increase of the amplitude tends to be lowered by VPA.

Adolescent↗

PubMed1999

Functional imaging in reading epilepsy: a case report.

Reading epilepsy is an uncommon epileptic syndrome preferentially related to the temporoparietal region of the language dominant hemisphere. We report ictal and interictal brain perfusion SPECT images in a 28-year-old woman who was reading epilepsy.

Adult↗

PubMed1998

Cavernous angioma presenting with hemidystonia.

We present a 34-year-old woman with right hemidystonia. She had a cavernous angioma (CA) of left thalamo-mesencephalic junction, revealed by magnetic resonance imaging (MRI). Her symptoms were moderately alleviated by biperiden 20 mg daily. We identified 11 patients reported in the literature to have movement disorders due to a cavernous angioma. None of them presented with hemidystonia. Some clinical properties of patients with CA associated with a movement disorder were evaluated.

Adult↗

PubMed1996

The one-and-a-half syndrome in systemic lupus erythematosus.

We report a case of one-and-a-half syndrome occurring as the first manifestation of central nervous system (CNS) involvement in systemic lupus erythematosus (SLE). The lesion in the pons was documented with magnetic resonance imaging (MRI). The patient responded quite satisfactorily to high-dose i.v. methyl-prednisolone therapy.

Aged↗

PubMed1992

Sneddon's syndrome associated with anticardiolipin antibody: a case report.

We report the case of a young man suffering from the rare combination of livedo reticularis and recurrent ischemic cerebrovascular disease (Sneddon's syndrome). He also had a circulating anticardiolipin antibody. in the absence of systemic lupus erythematosus, we suggest the likelihood of a primary antiphospholipid syndrome.

Adult↗