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Biomedical subjects

A Zidi

Publications and source records attributed to A Zidi.

13 recordsLinked to original sources

[Thoracic involvement in Behçet's vasculitis].

Thoracic involvement of Behcet's disease is unusual but serious. It is related to the well known vascular tropism of the disease. It may involve the superior vena cava, pulmonary arteries, aorta and subclavian vessels. Imaging is useful for diagnosis and assess the degree of thoracic involvement. CT scan and MRI are obviously more accurate than angiography. The spectrum of thoracic manifestations of the disease is presented based on a review of 22 cases.

Aneurysm↗

[Hydatid cyst of the mediastinum: 14 case reports].

PURPOSE: The objective of this study was to describe the different radiological features of the hydatid cyst of the mediastinum. MATERIALS AND METHODS: We conducted a retrospective study on 14 patients (seven women, seven men), diagnosed with mediastinal hydatid cyst, aged 13-67 years (mean, 48 years) over a period of 16 years in our hospital where 71 cases of hydatid disease are annually diagnosed. The patients were explored by chest radiography (n=14), chest ultrasonography (n=10), abdomen ultrasonography (n=14), computed tomography (CT scan) (n=13), and magnetic resonance imaging (MRI) (n=8). RESULTS: The chest x-ray showed an opacity of the anterior (n=11), middle (n=1), and posterior (n=1) mediastinum. The thoracic ultrasound confirmed the liquid nature of the mass with a multivesicular aspect (n=9). CT and thoracic MRI made it possible to precisely locate the mediastinal compartment involved and study the relationship to adjacent structures. A purely mediastinal location was found in only six cases. In the remaining cases, it was associated with hepatic (n=7) and pleural (n=1) locations. CONCLUSION: Hydatid cysts of the mediastinum are very uncommon. Diagnosis can be made by chest sonography. CT scan is the main tool for diagnosis and the study of possible extension. Our study showed a more frequent location to the anterior mediastinum.

Adolescent↗

[Abundant hemothorax revealing extralobular pulmonary sequestration].

Hemothorax is an exceptional, serious and misleading manifestation of extralobular sequestration. We report the case of a 15-year-old patient who consulted for chest pain and sudden onset dyspnea. The chest x-ray revealed fluid pleural effusion. Pleural puncture produced a bloody fluid and the angioscan showed a hyperdense formation without a systemic artery. Thoracotomy was performed. A left intrapleural pyramidal formation vascularized with a pedicle from the thoracic aorta was identified and sequestrectomy performed. At two years, the patient has remained symptom free. Extralobular sequestration is an exceptional cause of hemothorax. The absence of an aberrant systemic vessel on the angioscan should not rule out the diagnosis of sequestration. Precautions must be taken at surgery to avoid vessel damage.

Adolescent↗

[Febrile osseous pain in children with sickle cell disease: MRI findings].

PURPOSE: The aim of this study was to report the MRI findings that can suggest a vaso-occlusive crisis in cases of febrile osseous pain in children suffering from sickle cell disease. MATERIALS AND METHODS: MRI (T1 and T2 weighted sequences and T1 weighted sequence with fat saturation before and after gadolinium injection) was performed in 10 children with sickle cell disease, presenting with febrile osseous pain. The diagnosis of vaso-occlusive crisis was made after fast improvement due to symptomatic treatment and negative bacteriological result. RESULTS: MRI was abnormal in all cases. A multifocal localisation was found in 2 cases. Bone marrow abnormalities were constant. In 10 cases, high T1 and T2 signal and metaphyso-diaphysial lesions were noted. Heterogeneous medullar enhancement with "ink stain" feature was constant. Early periosteal abnormalities were noted in 8 cases with inflammatory or stratified features. Cortical thinning was found in 1 case. Soft tissue abnormalities were observed in 5 cases with inflammatory features in 4. CONCLUSION: Multifocal synchronous localisation, medullar abnormalities resulting from hemoglobin degradation, heterogeneous enhancement, early periosteal abnormalities and associated soft tissues swelling are MRI findings suggesting acute vaso-occlusive disease.

Adolescent↗

[Idiopathic pulmonary hemosiderosis in adults].

Idiopathic pulmonary hemosiderosis (IPH) is a rare cause of diffuse alveolar hemorrhage characterized by abnormal deposition of hemosiderin iron in the macrophages of alveoli. Most cases occur in children. In adults, IPH is rare: almost 10 cases reported during the late 10 years. We report the case of a 20-year-old-girl with IPH. There was no evidence of pulmonary vasculitis or capillaritis. Long-term treatment with systemic corticosteroids was followed by clinical remission lasting 4 years.

Adult↗

Tracheobronchopathia osteochondroplastica presenting as a respiratory insufficiency: diagnosis by bronchoscopy and MRI.

Tracheobronchopathia osteochondroplastica (TO) is a rare benign disorder affecting the trachea and occasionally the bronchi. We report a case of TO presenting as a respiratory insufficiency. Chest radiograph revealed an irregular narrowing of the intra thoracic trachea and a parenchymal consolidation of the left lower lobe. Magnetic resonance examination of the chest showed a diffuse irregular thickening of the trachea and central bronchi, which had an intermediate signal intensity with punctiform low signal intensity suggesting calcifications and no contrast enhancement. The diagnosis was confirmed by bronchoscopy and biopsies.

Adult↗

[Ultrasonographic, CT, and MRI findings of chest wall hydatidosis].

The chest wall is an uncommon localization for hydatid disease even in countries where echinococcosis is endemic. Only isolated sporadic cases have been reported in the literature. We reviewed retrospectively 15 patients who underwent surgery for chest wall hydatid disease. Various imaging techniques were used for diagnosis of our cases. These included chest radiograph, thoracic ultrasonography, computed tomography and magnetic resonance imaging. Hydatid cyst involved soft tissues (n=5), ribs and vertebrae (n=5), ribs (n=4) and sternum (n=1). Imaging techniques were of value for diagnosis (radiographs and sonography) and for evaluation of the extent of involvement (CT and MRI). Chest wall hydatidosis requires surgical treatment but recurrence is frequent.

Adolescent↗

[Value of CT scanning in the investigation of thoracic sarcoidosis].

INTRODUCTION: Sarcoidosis is a systemic disease of unknown aetiology that includes a pulmonary or mediastinal component in 90% of cases. The aim of this study is to clarify the contribution of thoracic CT scanning in the diagnosis and differential diagnosis of sarcoidosis and its role in the follow-up and the evaluation of the activity of the disease. METHODS: It is a retrospective study of 39 patients with histologically confirmed sarcoidosis. All patients had one or more thoracic CT scans. RESULTS: The most common parenchymatous lesions were lymphatic micronodules and peri-bronchovascular thickening. The right paratracheal chain and the hilar nodes were the most frequently involved. CONCLUSIONS: The CT scan is better than the chest x-ray at studying the parenchymal lesions and lymph node involvement in sarcoidosis. It helps in the differential diagnosis of sarcoidosis and other granulomatous disorders, especially tuberculosis. It also allows follow up of patients for the detection of complications, particularly fibrosis. Its role in the assessment of disease activity remains controversial.

Adult↗

[Tuberculosis of the lung bases].

Tuberculosis of the lung bases is a rare condition that can mimic pneumonia, bronchial carcinoma, lung abscess or bronchiectasis. Diagnostic delays, that can lead to serious complications not amenable to surgical resection, are often the result of repeatedly negative bacteriological examinations. We report a series of 10 cases of tuberculosis of the lung bases collected between 1993 and 1998 that were examined by computerised tomography. The chest x-ray most commonly showed a heterogeneous opacity. On the CT scan this corresponded with an area of alveolar consolidation which, when it was associated with centrilobular micronodules and cavitated nodules and masses, suggested the diagnosis of basal tuberculosis. Indeed the absence of apical lesions and the frequency of involvement of mediastinal and bronchial lymph nodes support the hypothesis of bronchial dissemination of the bacilli from tuberculous nodes. This explanation is supported by the high incidence of endobronchial lesions found at bronchoscopy in this form of tuberculosis.

Adult↗

[Carotid body tumors: contribution of the various imaging techniques. A report of six cases].

INTRODUCTION: Carotid body tumors are rare hypervascular lesions arising from neural crest paraganglion cells. MATERIALS AND METHODS: We retrospectively analyzed the imaging features of six patients with carotid body tumors to precise their imaging characteristics in order to find specific signs and elaborate a strategy for diagnosis. RESULTS: Imaging features detect the vascular nature of these tumors of the carotid space causing characteristic widening of the carotid bifurcation. Two patients had multiple (two or more) localizations and one had a family history of glomus tumor. CONCLUSION: MRI with MRA is considered as the gold standard imaging technique for the evaluation of glomus tumors as it allows a multiplanar approach which is important in the preoperative study.

Adult↗

[Pulmonary hyalinizing granuloma: review of two cases].

Pulmonary hyalinizing granuloma is a rare fibrosing nodular disease of the lung characterized by solitary or multiples pulmonary nodules. This report describes two cases of this rare disorder. MRI was available in one case. For the first case, the stability of the lesions and past history of retroperitoneal fibrosis suggested the diagnosis. For the second case, open lung biopsy was required for diagnosis. When multiple nodules are present, metastatic disease cannot be excluded and biopsy may be required. Evolution is usually benign but follow up is necessary.

Biopsy↗