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Biomedical subjects

A Zupi

Publications and source records attributed to A Zupi.

At least 19 recordsLinked to original sources
PubMed2004

Gemination of maxillary incisors.

Gemination is defined as a shape anomaly of teeth caused by an incomplete division of a single tooth bud. Its aesthetic and functional implications usually require a complex endodontic, restorative, periodontal, surgical, and orthodontic treatments. Three cases of gemination of maxillary incisors, resolved by different therapeutic approaches, are reported. The 1st case (germination of 2.1) was resolved by a simple crown-plasty. The 2nd case (gemination of 1.1 and 2.1) was resolved by a crown-plasty of 2.1 and an interradicular section of 1.1 with extraction of lateral root. The 3rd case (2.2 supernumerary and gemination of 1.2) was resolved by sacrifice of 1.2, extraction of 2.2 and its implantation in 1.2 region. In order to obtain an acceptable aesthetic and functional restoration, as in the cases presented, a good team-work, where all the specialists contribute to the selection of the more suitable treatment possible, is mandatory.

Adult↗
PubMed2002

Morbidity by plating in maxillofacial surgery.

BACKGROUND: Aim of this paper is to define the behaviour of osteosynthesis plates in maxillofacial area and to determine when to remove them. METHODS: The records of 123 patients treated with osteosynthesis plates were retrospectively assessed. Each case had a follow-up of not less than 5 years. Removal as a consequence of poor surgery was excluded from the study. RESULTS: Osteosynthesis occurred in the mandible in 198 cases and in the upper maxilla in 146 cases, with a further 23 cases treated by plating in other sites. Plates were removed in 21 cases; the most frequent cause of removal was infection (13 sites) followed by nerve palsy and dehiscence. CONCLUSIONS: Infections are without doubt the main cause of plate removal. In orthognathic patients, infections occurred less frequently, nevertheless they remain the main complication. Dysesthesia, along with infections, are the most frequent cause of removal. Plate exposure very rarely are reduction and fixation lost; thus the removal of the plate can be delayed.

Bone Diseases, Infectious↗
PubMed2001

Surgical therapy of parotid hemangiomas.

The goal of this review is to define the clinical characteristics of parotid hemangiomas in children and outline their therapeutic management. The records of 42 pediatric patients with hemangiomas were reviewed; 10 required surgical treatment. Two cases of temporary postoperative facial nerve palsy were observed. Treatment was commonly delayed, and there is a significant likelihood of spontaneous regression. The indications for surgical intervention are an increase in tumor size, rapid tumor growth, failure of tumor size to decrease and hemorrhage into the lesion.

Child, Preschool↗
PubMed2001

Intraosseous mucoepidermoid carcinoma. Report of a long-term evolution case.

Primary central mucoepidermoid carcinoma (CMC) of the jaws accounts only for 2-3% of all mucoepidermoid carcinomas reported. Bhaskar in 1963 first analysed the criteria for his central origin, histology and pathogenesis. The authors report a long-term evolution case of CMC of the mandible with peculiar clinical features observed at the Department of Maxillo-Facial Surgery of the School of Medicine and Surgery of the "Federico II" University of Naples (Naples, Italy) examining histopathologic and clinical features and problems related to the treatment.

Carcinoma, Mucoepidermoid↗
PubMed2000

Aggressive cemento-ossifying fibroma of the jaws.

The cemento-ossifying fibroma is probably the most frequent fibro-osseous lesion seen by oral pathologists. Occasionally, reports of lesions behaving in an aggressive fashion appear in the literature. At the present time, the relationship if these "aggressive" lesions to the "usual" fibromas is unclear. Two cases of "aggressive" cemento-ossifying fibroma are reported. Certainly, clinical, radiological, and histological characteristics of aggressive and usual fibromas do coincide. There are, however, diverging features warranting separation of different forms. These mild differences may be detected during preoperative assessment of the lesion, allowing a diagnosis of aggressive form to be made.

Adult↗
PubMed1999

Surgical management of the neck in squamous cell carcinoma of the tongue.

If the nodes are involved, survival of patients with squamous cell carcinoma of the tongue is considerably reduced. Surgery remains the treatment of choice and, to define its role, we have reviewed 82 consecutive cases. Sixty-two cases (76%) were T1-2, and 46 patients (56%) had involved nodes. The cervical region II was the most often involved (n=26). Occult nodal metastases were present in 12 cases. The extent of nodal spread and prognosis varies according to whether the body or the base of the tongue is involved. Lesions of the base with involved node should be treated by a selective posterolateral neck dissection, whilst in the case of a lesion of the body of the tongue, the dissection should be selective anterolateral. In lesions of the base, when there are no nodes involved, a prophylactic selective posterolateral neck dissection is recommended, whilst in the case of the lesions of the body, selective supraomohyoid neck dissection in T2-4 lesions is recommended.

Adult↗
PubMed1998

Perineural invasion of the lower alveolar nerve by oral cancer: a follow-up study of 12 cases.

Twelve previously untreated cases of oral cancer with perineural infiltration were studied retrospectively. Age, sex, site, clinical stage and outcome were evaluated. Management of the neoplasm in each case involved surgical removal and six patients required adjuvant radiotherapy. The most frequent site was the lip. At the time of diagnosis, five patients had sensory complaints and palpable lymphadenopathy was observed in three patients. The 5-year crude survival rate was 16.7%. In the cases with postoperative assessment of perineural infiltration, a median survival time of 30.8 months was observed; while in the case of preoperative assessment of nerve infiltration, extensive surgery was performed with a consequent median survival time of 44.5 months. The perineural infiltration of the lower alveolar nerve is more common (6.3%) than is generally thought. This frequency is due to the relationship with the lower lip and the mandibular region. In carcinoma of the lip, spread is generally limited to 10-15 mm along the lower alveolar nerve. In carcinoma of the mandibular region, spread is entirely dependent on the location of the tumour; the absence of clinical fixation to the bone and the small size of the carcinoma does not preclude the possibility of bone involvement. Neurological symptoms should be evaluated carefully, and a radiographic investigation of the nerve canal is mandatory.

Adult↗
PubMed1998

Surgical management of the neck in squamous cell carcinoma of the floor of the mouth.

Nodal involvement in squamous cell carcinoma considerably lowers survival rate. Despite its importance, neck management has still not been adequately explored. The Authors have retrospectively reviewed the records of 112 cases. Unilateral N+ were treated with a homolateral therapeutic and a controlateral prophylactic neck dissection; bilateral N+ were treated with a bilateral therapeutic neck dissection. On first observation the majority of cases (66.1%) were T1-2, N+ patients accounted for 45.5%. Among N- patients, 21.3% of occult nodal metastases were observed. The 5-year survival rate was 52.7%. With N+ lesions, a radical neck dissection should be performed; the dissection should be performed bilaterally. With N- lesions a prophylactic modified radical neck dissection is recommended in T2-4 lesions.

Adult↗
PubMed1997

Accuracy of fine needle aspiration biopsy in head and neck tumors.

PURPOSE: Fine-needle aspiration biopsy (FNAB) is frequently used in the diagnosis of lesions occurring in the head and neck region. This study evaluated the correlation between the findings on FNAB and the histological findings observed after surgery. MATERIALS AND METHODS: A review of 218 patients who underwent FNAB of a head or neck tumor was performed. Cytological reports were classified into the following diagnostic categories: negative or positive for malignant cells and unsatisfactory. False-positive, false-negative, true-positive (sensitivity), and true-negative (specificity) rates were calculated. RESULTS: Twelve specimens did not allow an adequate diagnosis (5.5%). Among benign tumors, 96.2% of the cases were correctly diagnosed, and 3.8% were nondiagnostic specimens. Among malignant tumors, 86.4% of cases were correctly identified. There were two (3.4%) false-negatives and six (10.2%) nondiagnostic specimens, with a total false-negative rate of 13.6%. CONCLUSIONS: Sampling errors present a minor problem with FNAB. Most nondiagnostic or incorrect specimens were caused by nonhomogenous lesions, with poor placement of the needle and an insufficient amount of aspirated material. FNAB is a useful modality for the diagnosis of head and neck masses.

Adenolymphoma↗
PubMed1997

Detection of latero-cervical metastases from oral cancer.

In squamous cell carcinoma of the oral cavity, the presence of nodal metastases greatly influences prognosis. The evaluation of regional lymph nodal involvement is crucial in the correct management of these neoplasms. The records of 45 patients with oral cancer were reviewed retrospectively to evaluate the accuracy and prognostic value of the techniques used to detect lymph node metastasis in the neck (clinical examination, echo-colour-Doppler, computed tomography and magnetic resonance imaging). Echo-colour-Doppler was the most accurate procedure with a predictive positive value of 95.6% and the lowest false-negative rate. Therefore, a diagnostic preoperative study must include echo-colour-Doppler preferably associated with computed tomography to achieve the greatest diagnostic accuracy.

Adult↗
PubMed1997

[Pathological fractures of the mandible caused by cancer of the oral cavity].

The pathological fracture of the mandible is a rare and undesirable consequence of cancerous bone invasion. This study investigates the retrospective incidence of this phenomenon in diagnosed cases of squamous cell carcinoma of the mandibular region, and reviews the methods of treatment used. A total of 194 patients with squamous cell carcinoma of the mandibular region were observed. Only six cases of pathological fractures were found. The treatment was conditioned by the need to eliminate the tumor, and was carried out in different methods according to the individual cases. This study underlines the importance of both knowing various techniques and collaborating with other specialists in treating the fracture.

Adult↗
PubMed1997

Cervical metastases from pulmonary epidermoid carcinoma.

A patient with a right latero-cervical swelling of three-months history was observed. Fine needle aspiration biopsy showed the presence of metastases of epidermoid carcinoma moderately differentiated. No signs or symptoms of head and neck neoplasm were presents. After instrumental evaluation the primary neoplasm was localised at the left lung and metastases were also localised in the right submandibular gland. Although metastases from pulmonary epidermoid carcinoma are normally bloodborne, in this case lymphatic metastases involving cervical areas were present, probably secondarily the submandibular involvement.

Biopsy, Needle↗
PubMed1996

Accuracy in the diagnosis of mandibular involvement by oral cancer.

Cancer of the mandibular region usually has a poor prognosis; this is particularly correlated to invasion of the mandible. To reduce the consequences of poor therapeutic planning, careful preoperative assessment of bone infiltration is necessary. We have examined the records of 50 patients evaluated by clinical examination, conventional radiography, computed tomography (CT), bone scintigraphy with 99mTc and magnetic resonance imaging (MRI). The highest sensitivity (100%) was attained by scintigraphy; the highest values of specificity (96.3%) were reached by CT scan and MRI. A CT scan showed the highest predictive positive value (95.4%) and efficiency (94%), this plus MRI have good values and the associated sensitivity and efficiency are higher than when these techniques are used alone.

Adult↗
PubMed1996

Swelling of the floor of the mouth: a clinical dilemma.

Swelling of the floor of the mouth is sometime difficult to diagnose clinically. Lithiasis and neoplasm are the most frequent causes of intraoral swelling. Also after plain radiology and computed tomography the diagnosis is often dubious. A case of swelling of the floor of the mouth due to an adenoid cystic carcinoma of the sublingual gland is reported.

Biopsy, Needle↗