[Therapeutic endoscopy].
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Biomedical subjects
Publications and source records attributed to A de la Torre Bravo.
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The endoscopic resection of the mucosa of the digestive tract (ERM) is a set of techniques that have as their end the remotion of the mucosa for the diagnosis and treatment of localized diseases. The technique consists of the elevation of the mucosa with a submucosa injection of liquid or with suction in the interior of a transparent overtube. The procedure is indicated in the treatment of incipient malignant tumors of the esophagus, stomach, and colon, with a success rate that vacillates between 60 and 95%. An indispensable condition is the precise selection of patients through endoscopy and high-frequency endoscopic ultrasound. Other indications are the resection of flat and sessile polyps, the biopsies of submucosa tumors, and the taking of biopsies of great volume for the study of infiltrating and inflammatory neoplastic diseases. Based on the literature, principally descriptive and not comparative, the treatment of incipient digestive tract carcinomas with ERM has encountered serious difficulties in the Western world because of the rarity of the diagnosis, the scarce availability of endoscopic ultrasound, and lack of information of long-term results. On the other hand, in the diagnostic field of mucosa diseases, and in the treatment of polyps, its utility is evident. In conclusion, ERM is added to the new endoscopic techniques for the obtaining of specimens of great volume and for the resection of sessile polyps. In the treatment of malignant tumors, ERM should be used with caution.
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We report our experience in the use of percutaneous cholangioscopy for extraction of retained stones in the biliary tract, at the Oncology Hospital, Centro Médico Nacional, IMSS, between July 1984 and January 1990. Ninety seven patients were evaluated; the endoscopic manipulation was successful in 82 patients (84.5%). The main causes of failure were: narrow fistula, impacted stone, very small stones and false way. There were minor complications on 13 patients, but in two cases intestinal perforation indicated laparotomy. No death was reported. The main disadvantage of cholangioscopy was the waiting period, necessary to obtain a strong fistula. Nevertheless, the endoscopist can also relay on other techniques, such as sphincterectomy; the choice depends of each particular case.
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The definitive diagnosis of esophageal and gastric carcinoma rests upon histological confirmation of the lesion and it is one of the basis for planning the proper treatment. With the advent of exfoliative citology in 1947 the possibility of studying isolated cells detached from the esophagogastric mucosa became a reality. Later on, the development of the fiberoptic endoscopy permitted the direct observation of the lesion, and histological and citological diagnosis. In this report we publish the results obtained in 270 consecutive cases of esophageal and gastric carcinoma. The biopsies were positive in 86.2% of the cases and the citology was positive in 61.8% of the cases. Both procedures combined yielded 90.3% of positive results. Most false negative studies were related to lesions located in the cervical esophagus, and in the esophago-gastric junction, It is suggested that retrograde esophagoscopy through a gastrostomy could improve the results. The false negative cases of gastric carcinoma are related to inadequate gastric evacuation or to submucosal extension of the tumor. The adequate handling of the specimens is vital if good standards are to be kept.
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