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Biomedical subjects

A el-Din

Publications and source records attributed to A el-Din.

7 recordsLinked to original sources

Wallstent endoprostheses for the relief of prostatic urethral obstruction in high risk patients.

Twenty-one patients with prostatic urethral obstruction who were unfit for surgery were treated with self-expandable stainless steel endoprostheses inserted under fluoroscopic guidance. The procedure was technically successful in all patients, although in one case a second stent was required 2 months later. One patient developed a urethral stricture in the 12-16 month follow up period. One case of epididymoorchitis and one case of septicaemia after stenting were treated successfully with antibiotics. Endoprostheses represent a satisfactory alternative to prostatectomy in high-risk patients.

Aged

Self-expandable stainless steel braided endoprosthesis for biliary strictures.

A new type of biliary stent was inserted in 45 patients with symptomatic biliary strictures, 40 malignant and five benign. The stent is made of stainless steel woven into a tubular mesh. It is introduced in compressed form on a 7- or 9-F delivery catheter and released at the site of the stricture. Fully open, the stent has an internal diameter of 1 cm. The 30-day mortality was 7%. The early (less than 72 hours) complication rate was 16%. Recurrent jaundice occurred in 42%; late complications of sepsis without jaundice occurred in an additional 11%. None of the stents migrated. This new design allows a large-diameter stent to be inserted percutaneously without increased risk of complications. The frequency of recurrent jaundice, however, was not less than that observed with plastic stents, but this may have reflected the spectrum of patients treated, many with hilar strictures and previous interventions.

Aged

[Percutaneous implantation of vascular endoprostheses (stents) in the iliac and femoral arteries].

Flexible, self-expanding metallic mesh stents were implanted via a percutaneous catheter delivery system, immediately after balloon dilatation, in 68 patients (59 males and 9 females; mean age 56.6 [40-73] years). All had stenoses or occlusion of the iliac or femoral arteries. The bridged vessel segments were 3.5-27 cm long; the stent lumen ranged from 6 to 12 mm diameter. Good blood flow was restored in all 68 patients. The Doppler sonographic index increased on average by 0.33 to a mean of 0.9 (0.4-1.2). An early stent occlusion occurred in three patients (one femoral artery with a stented length of 27 cm thrombosed after 24 hours, two iliac stents were found to be occluded four and eight weeks, respectively, after insertion). Transitory peripheral emboli occurred in two patients with femoral stents. In five patients (four with femoral stents, one with an iliac stent) marked intimal hyperplasia with stenosis developed after 4-10 months; in four of them they were successfully treated by the percutaneous technique. The described percutaneous stent placement method is suitable for treating arterial stenoses or occlusions which cannot be satisfactorily dilated by balloon, as well as restenoses and local complications after angioplasty. It is particularly effective in iliac arteries.

Adult

Venous stenoses in dialysis shunts: treatment with self-expanding metallic stents.

A flexible, self-expanding metallic endoprosthesis was employed for the treatment of venous outflow stenoses in four patients with a polytetrafluoroethylene shunt and two patients with a Brescia-Cimino shunt. The stenoses had led to shunt occlusion in five patients and to flow impairment in one. In the occluded shunts, thrombectomy and subsequent balloon angioplasty were performed in four patients, and percutaneous recanalization with angioplasty was performed in one. One shunt with decreasing flow was percutaneously dilated. Since the underlying stenoses recurred in four patients after 24 hours and did not respond sufficiently to angioplasty in two patients, up to four stents were placed in the venous segments. Thrombosis of the stents occurred in two patients after 24 hours and in one after 6 weeks and was successfully recanalized with thrombectomy in two. At 2-6 months follow-up, the stents and the shunts were patent in five patients. In three of these patients, intima hyperplasia, associated with narrowing of the stent lumen in two, was noted within 4 months after stent placement.

Adult

Iliac and femoral artery stenoses and occlusions: treatment with intravascular stents.

Forty-five patients with atherosclerotic stenoses and occlusions of the iliac and superficial femoral arteries were treated with a flexible, self-expanding, metallic intravascular stent. Of these patients, 37 were treated immediately after inadequate angioplasty. At a follow-up period of 2-12 months, intravenous digital subtraction angiograms demonstrated patency of the vessels with stents in 40 of 45 patients. The mean Doppler ankle/arm index increased from 0.60 to 0.92 immediately after treatment and was 0.89 at follow-up. Early thrombotic stent occlusion occurred in two patients. Intimal hyperplasia was a late effect and led to stent stenoses in three patients after 5-9 months and stent occlusion in one patient after 6 months. In three patients, percutaneous recanalization with balloon and Simpson catheters was successful. Intravascular stents proved particularly useful for maintenance of patency after angioplasty in occlusions of the iliac and femoral arteries and in treatment of stenoses due to eccentric and severely ulcerated plaques. The stents also helped manage complications after angioplasty. Long-term results will depend on the degree, frequency, and progression of intimal hyperplasia narrowing the vascular lumen.

Adult