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Biomedical subjects

AB Einstein

Publications and source records attributed to AB Einstein.

14 recordsLinked to original sources
PubMed1995

Hormonal Therapy for Prostate Cancer: When to Use It.

Androgen deprivation has been the standard treatment for advanced prostate cancer. With the development of antiandrogen drugs, combination hormonal therapy achieving "total androgen blockade" has been demonstrated to be superior to monotherapy for patients with low-tumor-burden metastatic disease. Combination therapy is now being used more aggressively in locally advanced disease, with phase II studies suggesting benefit as measured by prolonged disease-free survival. Phase III randomized, controlled trials currently are being conducted.

Journal Article↗
PubMed1995

Therapeutic Approaches to Invasive Bladder Cancer in the Elderly Patient.

Invasive transitional cell carcinoma (TCC) of the bladder is a potentially life-threatening problem. Radical cystectomy and full-dose radiation therapy have been the standard approaches to controlling local disease and, in some cases, may be curative. However, 60% or more of treated patients die of metastatic disease. Newer approaches using active chemotherapeutic drug combinations, both before and after primary local therapy, may downstage local tumors but have not yet been demonstrated to increase the overall survival rate. Choice of combined modality therapy should take into consideration the primary tumor stage, potential treatment-related toxicities and morbidities, the patient's functional status, present and past medical problems, and treatment preference, but not age alone.

Journal Article↗