Biomedical subjects

AJ Rae

Publications and source records attributed to AJ Rae.

3 recordsLinked to original sources

PubMed1994

Helicobacter pylori-induced Diarrhea Ileogastrostomy.

A retrospective study of all ileogastrostomy procedures (n = 26) performed in 1993 by one surgeon (IGMC) was carried out to investigate the hypothesis that Helicobacter pylori may be implicated in certain severe cases of postoperation nausea and diarrhea. Ten of 26 persons (38.5%) displayed nausea and notable diarrhea (greater than or equal to ten bowel movements per day), seven of which warranted upper GI investigation. One hundred per cent (seven of seven) of these persons were found to possess H. pylori upon C-14 breath test. In four of six cases eradication therapy (1 g amoxicillin b.i.d./20 mg omeprazole b.i.d. for 2 weeks) corresponded with a resolution of severe nausea and diarrhea (one additional case involved omeprazole use only), suggesting that H. pylori should be considered as a possible cause of these symptoms post-ileogastrostomy. Additionally, in four of seven cases persons were re-tested (C-14 breath analysis) at least 1 month post-therapy and in this group three persons were found to be free of the organism. All three cases of notable diarrhea and nausea resolved with treatment, providing the strongest evidence for a possible association between infection and these symptoms.

Journal Article↗

PubMed1994

Laparoscopic Ileogastrostomy.

Laparoscopic ileogastrostomy was successfully performed on two of three morbidly obese persons. In our first case, access ports proved too short and the patient was converted to an open procedure. Aims were to carry out surgery for the morbidly obese patient through a laparoscope and, as a consequence, increase ambulation, while reducing pain, morbidity, and the chance of apnea (due to impaired breathing in the first 24 h following conventional surgery). Length of laparoscopic surgeries for the second and third patients were 5 and 4 h, respectively, while hospital stays were 10 days and 5 days. Pulmonary function tests at 24 h were carried out and showed a great advantage in favor of the laparoscopic approach. Response of the medical team to this procedure was that it was more time-consuming and demanding than open surgery. Although gastric banding and gastric stapling have been accomplished laparoscopically, we believe these to be the first procedures with anastomoses carried out on morbidly obese patients.

Journal Article↗

PubMed1993

Quality of Life Assessment, of Ileogastrostomy.

Twenty of 26 (77%) consecutive Patients undergoing ileogastrostomy, performed by the same surgeon (IGMC) between February 1989 and May 1992, responded to a mailed quality of life survey. Average present weight was reported as 50.9 kg less than a mean preoperative weight of 139.7 kg. Mean time of follow-up was 24.75 months. When comparing perceptions before and after surgery, several quality of life improvements were noted in the areas of vocation, relationships, emotional well-being and physical well-being. Post-surgery, jobs were rated more satisfying, eating habits improved, self-image and self-confidence increased and body disparagement declined. Satisfaction with sexual relations increased, as did frequency. In general, relations with partners, coworkers and friends seemed to improve. Exercise also increased significantly. In contrast, foul flatus, bloating, and bowel movements regularly hampered activities or caused embarrassment when in public. Despite these physical side-effects, we observed that a large majority of persons undergoing ileogastrostomy noted significant improvements in quality of life.

Journal Article↗