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Biomedical subjects

Aaron R Biesbrock

Publications and source records attributed to Aaron R Biesbrock.

At least 19 recordsLinked to original sources
PubMed2003

Initial impact of a national dental education program on the oral health and dental knowledge of children.

Oral health educational programs have been reported to have a variable impact on the oral health status of program participants. This paper reports the impact of an educational oral health program conducted within a single Boys & Girls Club of America. The objective of this 4-week examiner-blind study was to determine the impact of the educational program on the gingival health (gingivitis and plaque) of participating children who were between the ages of 5 and 15. The multi-week program taught the participants the basics of oral biology and disease, as well as proper oral health prevention including oral hygiene, dietary modification, and the importance of visiting the dentist. A calibrated examiner measured whole mouth Loe-Silness Gingival Index (GI) and Turesky Modification of Quigley-Hein Plaque index (PI) at baseline (immediately prior to the initiation of the educational program) and 4 weeks later. The primary efficacy analysis was based on change from baseline for 75 subjects who were enrolled at baseline, participated in the educational program, and were examined 4 weeks later. Mean baseline GI score was 0.37, while the 4 week mean GI score was reduced to 0.18. This represents a 51% reduction in GI score with p<0.001. Mean baseline PI score was 3.80, while the 4 week mean PI score was reduced to 2.68. This represents a 29% reduction in PI score with p<0.001. In addition, subjects completed a questionnaire (5 questions) at baseline and at 4 weeks to assess their oral health knowledge. The subject population was found to have statistically significantly (p<0.05) greater knowledge with respect to optimal brushing time and optimal frequency of dental recall visits following the program at week 4. Collectively, these data support the role of the educational program in promoting improved oral health in these children over a one month period.

Adolescent↗
PubMed2003

Effect of three concentrations of sodium fluoride dentifrices on clinical caries.

PURPOSE: To assess whether the anti-caries effectiveness of three concentrations of fluoride dentifrice (placebo, 500 ppm F- and 1450 ppm F-) could be differentiated with small sample sizes in short time frames. MATERIALS AND METHODS: A controlled fluoride (F) dose-response study was conducted in concurrence with a supervised school oral hygiene regimen to assess whether dentifrices with increasing fluoride levels could be differentiated with small sample sizes in short time frames. The study was a randomized, double-blind study conducted for a period of 21 months. Subjects (N = 657 with approximately 219 per group) were randomized to placebo dentifrice, 500 ppm F- dentifrice or 1450 ppm F- dentifrice treatments for the first 9 months of the study. Subjects in the placebo group were then switched to either 500 ppm F- or 1450 ppm F- dentifrice for the remainder of the study, while subjects in the fluoride groups continued with their original treatment assignments. A calibrated examiner measured visual-tactile caries as DMFS that was supplemented with a radiographic examination at baseline, 9 months and 21 months for each subject. RESULTS: The mean caries increments at 9 months were 0.35 surfaces, 0.34 surfaces, and 1.28 surfaces for the 1450 ppm F-, 500 ppm F-, and placebo groups, respectively. The mean caries increments at 21 months were 0.21 surfaces, 0.26 surfaces, 1.75 surfaces and 1.90 surfaces for the 1450 ppm F-, 500 ppm F-, placebo/1450 ppm F-, and placebo/500 ppm F- groups, respectively. The 500 ppm F- and 1450 ppm F- fluoride dentifrices delivered statistically significantly (P< 0.05) lower DMFS scores than the placebo control dentifrice at 9 months, while at 21 months the 500 ppm F- and 1450 ppm F- fluoride dentifrices delivered statistically significantly lower DMFS scores as compared to the both the placebo/500 ppm F- and the placebo/1450 ppm F- dentifrice groups. There was no evidence of a dose response (1450 ppm F- < 500 ppm F-) at 9 months or at 21 months. In this study, the effectiveness of the two fluoride dentifrices was observed at 9 months and these outcomes were still present at 21 months, confirming that caries benefits can be observed in time frames as short as 9 months with approximately 200 subjects per treatment group.

Analysis of Variance↗
PubMed2003

The impact of bristle profile on plaque removal efficacy of a battery-powered toothbrush.

PURPOSE: To compare the plaque removal efficacy of a control powered toothbrush (original Crest SpinBrush, flat bristle profile) to a prototype powered toothbrush (new Crest SpinBrush, rippled bristle pattern). MATERIALS AND METHODS: This study was a randomized, controlled, examiner-blind, 4-period crossover design, which examined plaque removal following a single use. The 20 subjects repeated the single use in each of four periods, twice with each toothbrush. Plaque was scored before and after brushing using the Turesky Modification of the Quigley-Hein Index. RESULTS: Baseline plaque scores were 1.59 and 1.65 for the prototype powered toothbrush and control toothbrush treatment groups, respectively. With respect to all surfaces examined, the prototype powered toothbrush delivered an adjusted (via analysis of covariance) mean difference between baseline and post-brushing plaque scores of 0.54 while the control toothbrush delivered an adjusted mean difference of 0.48. The experimental toothbrush group, on average, had a 13.1% larger plaque removal score than the control toothbrush. These results were statistically significant (P= 0.031). Similar results were observed on buccal and lingual surfaces.

Adult↗
PubMed2003

Dental caries in school-age children residing in five Guatemalan communities.

OBJECTIVE: The caries epidemiology within the country of Guatemala is poorly understood. This work reports the cross-sectional prevalence of caries in the permanent teeth of children between the ages of 6 and 12 years in five different communities within Guatemala, and relates the caries experience to the fluoride levels in the communal drinking water in each of these cities. METHODOLOGY: These cities were selected because they represent geographically distinct regions of Guatemala, where there is no fluoridation of public drinking water. A total of 1,145 children were enrolled and examined in this study, with 227, 230, 231, 228 and 229 enrolled at Coban, Solola, Guatemala City, Chiquimula, and Estanzuela, respectively. Caries examinations were performed by a calibrated examiner using a visual tactile examination method performed with the aid of an artificial light, mouth mirror, compressed air, and a dental explorer employing a modified Radike criteria. Fluoride concentrations from drinking water, collected from the primary drinking water spigot at each elementary school in each city, were determined using ion chromatography. RESULTS: The cross-sectional mean DMFS in children 6-8 years old was 4.61, 4.34, 3.75, 3.52 and 2.71 for Coban, Solola, Guatemala City, Chiquimula, and Estanzuela, respectively. The cross-sectional mean DMFS in children 9-12 years old was 10.96, 10.09, 8.67, 8.71 and 6.02 for Coban, Solola, Guatemala City, Chiquimula, and Estanzuela, respectively. The prevalence of caries in children between the ages of 9 and 12 years was greater than 90% in all five cities. The natural fluoride concentration in water was 0.05 ppm, 0.23 ppm, 0.14 ppm, 0.50 ppm, and 0.60 ppm for Coban, Solola, Guatemala City, Chiquimula, and Estanzuela, respectively. CONCLUSION: Collectively, these data demonstrate that the high prevalence of caries in Guatemala appears to be directly correlated to levels of fluoride in the community drinking water.

Altitude↗
PubMed2003

Plaque removal efficacy of a prototype power toothbrush compared to a positive control manual toothbrush.

PURPOSE: Recently, a new experimental battery-powered toothbrush was developed as a second generation to Crest SpinBrush. The brush head of this new prototype toothbrush (Crest SpinBrush Pro) incorporates a dual moving head design with one oscillating and the other translating back and forth. The objective of this study was to compare the plaque removal efficacy of a positive control manual toothbrush (Oral-B Cross Action) to this prototype power toothbrush following a repeated single use study design. In addition, this paper reports the results of a study examining the relative plaque removal efficacy of the positive control manual toothbrush to seven representative manual toothbrushes. METHODS: This study was a randomized, controlled, examiner-blind, four-period crossover design, which examined plaque removal with the two toothbrushes following a single use in 40 subjects. Plaque was scored before and after brushing using the Turesky Modification of the Quigley-Hein Index. RESULTS: Baseline plaque scores were 2.61 and 2.66 for the prototype power toothbrush and control toothbrush treatment groups, respectively. With respect to all surfaces examined, the prototype power toothbrush delivered an adjusted (via analysis of covariance) mean difference between baseline and post-brushing plaque scores of 0.98 while the control toothbrush delivered an adjusted mean difference of 0.74. The experimental toothbrush group, on average, had a 32.8% larger plaque removal score than the control toothbrush. These results were statistically significant (P < 0.001). Similar results were observed on buccal and lingual surfaces. In addition, results from the study comparing manual toothbrushes showed that the positive control manual toothbrush had higher plaque removal scores compared to seven representative manual toothbrushes. The plaque removal score differences reached statistical significance for five of the seven toothbrushes.

Adult↗
PubMed2003

The prevention of induced stain using two levels of sodium hexametaphosphate in chewing gum.

OBJECTIVE: This study was a randomized, controlled, examiner-blind, four-period crossover design that examined the prevention of induced stain deposition through the use of chewing gums containing either 2.0% or 3.0% sodium hexametaphosphate (Na Hex). METHODOLOGY: The test treatments were an experimental chewing gum containing 2.0% Na Hex, a second experimental chewing gum containing 3.0% Na Hex, a placebo chewing gum (0.0% Na Hex) and no chewing gum. The study was carried out over a four-week period, with each treatment period lasting two days. Treatment periods were separated by a washout period of three to five days. Twelve subjects who met the inclusion and exclusion criteria were given a thorough dental prophylaxis limited to the anterior twelve teeth, and then underwent a baseline digital imaging assessment (DIA) procedure. Each treatment period involved two days of stain induction, which consisted of rinsing for 60 seconds with 10 ml of 0.12% chlorhexidine, followed by chewing with two pellets of the assigned chewing gum for five minutes or by no gum chewing, followed by rinsing with 10 ml of cold tea solution for 60 seconds. This regimen was repeated eight times throughout the day, approximately once an hour. Imaging was completed at baseline and at the end of day 2 of the induced stain regimen. Subjects refrained from any oral hygiene during the two-day stain induction periods. RESULTS: Average baseline L* scores ranged from 76.30 to 76.57. At the end of the two-day stain induction regimen (eight hourly cycles per day) when no gum was chewed ("no gum"), subjects' teeth were 5.18 units darker on average than they were at baseline. At the end of the two-day regimen when the placebo gum was chewed, subjects' teeth were 4.54 units darker on average than they were at baseline. The difference between "no gum" and placebo gum was statistically significant (p = 0.017), and represented a 12.4% reduction in tooth darkness for the placebo gum treatment. Use of the 2.0% Na Hex gum resulted in teeth 3.64 units darker on average versus baseline, and the 3.0% Na Hex gum resulted in teeth 4.02 units darker. Both the 2.0% and 3.0% Na Hex gums resulted in teeth that were statistically significantly less dark (p < or = 0.042) than both the "no gum" and placebo gum treatments. On average, the reduction in tooth darkness for the 2.0% Na Hex gum was 29.7% versus "no gum" and 19.8% versus the placebo gum. The 2.0% Na Hex and 3.0% Na Hex gum treatments did not differ significantly (p = 0.114). CONCLUSION: This study demonstrated that 2.0% and 3.0% levels of Na Hex in a chewing gum prevented the deposition of extrinsic dental stain better than a chewing gum without Na Hex, which in turn prevented the deposition of stain better than no chewing gum.

Adult↗
PubMed2003

A plaque removal study comparing two advanced-design oscillating battery-powered toothbrushes.

OBJECTIVE: The objective of this study was to compare the plaque removal efficacy of two advanced-design battery-powered toothbrushes (Crest SpinBrush Pro and Oral-B CrossAction Power) following a single use. METHODOLOGY: This study was a randomized, controlled, examiner-blind, four-period crossover design, which examined plaque removal with the two toothbrushes following a single use by 40 subjects. Plaque was scored before and after brushing using the Turesky Modification of the Quigley-Hein Index. RESULTS: Average baseline plaque scores were 2.915 and 2.883 for the SpinBrush Pro and CrossAction Power toothbrush treatments, respectively. The SpinBrush Pro toothbrush delivered an adjusted (via analysis of covariance) mean difference between baseline and post-brushing plaque scores of 0.802, while the CrossAction Power toothbrush delivered an adjusted mean difference of 0.667. The SpinBrush Pro toothbrush, on average, had 20.2% greater plaque removal scores relative to the CrossAction Power toothbrush. These results were statistically significant (p < 0.001). The observed results on the buccal and lingual surfaces were consistent with the overall results, and were statistically significant. CONCLUSION: The results of this study support the conclusion that the SpinBrush Pro removes statistically significantly greater amounts of plaque over a one-minute brushing period compared to the CrossAction Power toothbrush.

Adult↗
PubMed2003

Dose response efficacy of sodium fluoride dentifrice at 9 and 21 months with supervised brushing.

PURPOSE: To assess whether a fluoride dose response could be detected with a relatively small sample size in a short duration using a novel randomized, double-blind study design. METHODS: Subjects (N = 644, with approximately 215 per group) with a mean age of 10.4 years old (9-12 years old) used a placebo dentifrice, an 1100 ppm F dentifrice or a 2800 ppm F dentifrice for the first 9 months of the study. Subjects in the placebo group were then switched to either 1100 ppm or 2800 ppm F dentifrice for the remainder of the study, while subjects in the fluoride groups continued with their original treatment assignments. Three calibrated examiners measured visual-tactile caries as DMFS that was supplemented with a radiographic examination at baseline, 9 months and 21 months for each subject. RESULTS: The results of this study are consistent with the previous results reported for sodium fluoride dentifrices. For all examiners, the 1100 ppm and 2800 ppm fluoride dentifrices delivered statistically significantly (P < 0.05) lower DMFS scores than the placebo control dentifrice at 9 months, while at 21 months the 1100 ppm and 2800 ppm fluoride dentifrices delivered statistically significantly lower DMFS scores compared to the both the placebo/1100 ppm and the placebo/2800 ppm dentifrice groups. In addition, one of the three examiners observed a directional (P = 0.11) dose response (2800 ppm F < 1100 ppm F) at 9 months, while at 21 months all three examiners observed evidence of a dose response, with one examiner observing a statistically significant difference between 1100 ppm and 2800 ppm F. Caries scores on occlusal surfaces provided the strongest evidence of an 1100 ppm F vs. 2800 ppm F difference.

Cariostatic Agents↗
PubMed2002

The clinical effectiveness of a novel power toothbrush and its impact on oral health.

This review details the invention and clinical testing of a new power toothbrush designed to provide a low cost, effective toothbrush, which has a combination of a round oscillating head in conjunction with fixed bristles. The data demonstrate this power toothbrush (Crest SpinBrush) is an effective cleaning toothbrush with respect to plaque removal. Four independent 4-period crossover studies, where subjects used each brush twice, have demonstrated that brushing with this power toothbrush results in 10-40% greater plaque removal relative to a series of control manual toothbrushes. Separate research has confirmed that adults and children tend to brush longer, 35.8% and 38.3% respectively, when using this power toothbrush relative to manual toothbrushes. In addition, it has been shown to be superior to a battery-powered toothbrush (Colgate ActiBrush) in two independent studies and has demonstrated comparable efficacy to a leading powered toothbrush (Oral-B Ultra Plaque Remover). In parallel, this power toothbrush has also been shown to be safe relative to manual and power toothbrushes.

Adult↗
PubMed2002

Comparative efficacy of two battery-powered toothbrushes on dental plaque removal.

A number of clinical studies have consistently demonstrated that power toothbrushes deliver superior plaque removal compared to manual toothbrushes. Recently, a new power toothbrush (Crest SpinBrush) has been marketed with a design that fundamentally differs from other marketed power toothbrushes. Other power toothbrushes feature a small, round head designed to oscillate for enhanced cleaning between the teeth and below the gumline. The new power toothbrush incorporates a similar round oscillating head in conjunction with fixed bristles, which allows the user to brush with optimal manual brushing technique. The objective of this randomized, examiner-blind, parallel design study was to compare the plaque removal efficacy of a positive control power toothbrush (Colgate Actibrush) to an experimental toothbrush (Crest SpinBrush) following a single use among 59 subjects. Baseline plaque scores were 1.64 and 1.40 for the experimental toothbrush and control toothbrush treatment groups, respectively. With regard to all surfaces examined, the experimental toothbrush delivered an adjusted (via analysis of covariance) mean difference between baseline and post-brushing plaque scores of 0.47, while the control toothbrush delivered an adjusted mean difference of 0.33. On average, the difference between toothbrushes was statistically significant (p = 0.013). Because the covariate slope for the experimental group was statistically significantly greater (p = 0.001) than the slope for the control group, a separate slope model was used. Further analysis demonstrated that the experimental group had statistically significantly greater plaque removal than the control group for baseline plaque scores above 1.43. With respect to buccal surfaces, using a separate slope analysis of covariance, the experimental toothbrush delivered an adjusted mean difference between baseline and post-brushing plaque scores of 0.61, while the control toothbrush delivered an adjusted mean difference of 0.39. This difference between toothbrushes was also statistically significant (p = 0.002). On average, the results on lingual surfaces demonstrated similar directional scores favoring the experimental toothbrush; however these results did not achieve statistical significance. In conclusion, the experimental Crest SpinBrush, with its novel fixed and oscillating bristle design, was found to be more effective than the positive control Colgate Actibrush, which is designed with a small round oscillating cluster of bristles.

Adult↗
PubMed2002

Dental plaque removal with a novel battery-powered toothbrush.

PURPOSE: To compare the plaque removal efficacy of a positive control power toothbrush (Oral-B Ultra Plaque Remover) to an experimental power toothbrush (Crest SpinBrush) following a single use. MATERIALS AND METHODS: This study was a randomized, controlled, examiner-blind, 2-period crossover design which examined plaque removal with the two toothbrushes following a single use in 38 completed subjects. Plaque was scored before and after brushing using the Turesky Modification of the Quigley-Hein Index. RESULTS: Baseline plaque scores were 1.89 and 1.91 for the experimental toothbrush and control toothbrush treatment groups, respectively. With respect to all surfaces examined, the experimental toothbrush delivered an adjusted (via analysis of covariance) mean difference between baseline and post-brushing plaque scores of 0.46 while the control toothbrush delivered an adjusted mean difference of 0.45. These results were not statistically significant (P=0.645). A 95% one-sided upper confidence limit on the Ultra Plaque Remover minus SpinBrush difference in amount of plaque removed was calculated as 9.4% of the Ultra Plaque Remover adjusted mean. A common criterion for what is known as an "at least as good as" test is that the 95% one-sided confidence limit on the product difference is below 10% of the control product mean. Using this criterion, the SpinBrush is at least as good as the Oral-B Ultra Plaque Remover. With respect to buccal and lingual surfaces, the experimental toothbrush delivered very similar results relative to the control toothbrush. These results were also not statistically significant (P> 0.564).

Adult↗
PubMed2002

Caries prevention in Chinese children with sodium fluoride dentifrice delivered through a kindergarten-based oral health program in China.

Caries in China appears to be a significant problem, especially among preschool children. The effect of caries prevention in the primary teeth of preschool children through the use of fluoridated dentifrices and prevention programs has not been widely addressed. The purpose of this study was to examine the caries preventive effects of an 1100 ppm sodium fluoride dentifrice used in the context of a kindergarten-based oral health program compared to a matched placebo dentifrice in the absence of a kindergarten-based oral health program. This was a randomized, placebo-controlled, examiner-blind, two-year caries study. A population of 1,334 preschool school children, three years of age, was recruited from 24 school kindergartens in Huairoi and Miyun counties, located approximately 60 kilometers northeast of Beijing, China. Classrooms were stratified based on mean baseline dmfs scores derived from the visual-tactile baseline examination, and randomly assigned to one of the two dentifrice treatment groups: 0.243% sodium fluoride (1100 ppm fluoride ion) or placebo (0 ppm fluoride ion). Children attending the schools participating in the program brushed twice a day (morning and afternoon) at school under the supervision of classroom teachers during the school week. The children randomized to schools receiving the placebo dentifrice were supplied with toothbrushes and dentifrice for ad libitum use at home and did not participate in the school program or supervised classroom brushing. For the primary examiner, the two-year caries increment data demonstrated evidence of anticaries efficacy for the sodium fluoride dentifrice/school program group as compared to the placebo/no school program group. In the evaluable subset, the 1100 ppm fluoride treatment group had a 20.7% reduction in dmfs compared to the placebo treatment group, that was statistically significant (p = 0.004). The secondary examiner observed a similar overall treatment effect, as the 1100 ppm fluoride treatment group had an 22.1% reduction in dmfs compared to the placebo treatment group that was statistically significant (p = 0.014). In contrast to the primary examiner, there was a county-by-treatment interaction for the secondary examiner's results necessitating that the counties be examined independently. In Miyun county, the sodium fluoride/school program group had a 39.9% reduction in caries compared to the placebo/no program group that was statistically significant (p = 0.001). In Huairou county, the sodium fluoride/school program group had a 6.8% reduction in caries compared to the placebo/no program group that was not statistically significant (p > 0.05). These results demonstrate that fluoride in conjunction with increased dental awareness can deliver important reductions in caries in preschool children.

Cariostatic Agents↗
PubMed2002

Comparative clinical trials and the changing marketplace for oral care: innovation, evidence and implications.

The development of a trayless bleaching system (Crest Whitestrips) and a novel battery-powered toothbrush (Crest SpinBrush) has fueled growth in the bleaching and power toothbrush markets. Beyond offering convenient, low-cost options for patients, the effectiveness of each product is supported by a robust clinical program. New comparative research involving these products expands evidence on the clinical meaningfulness of the benefits of this whitening system and powered toothbrush for patient care.

Clinical Trials as Topic↗
PubMed2002

Dental plaque removal with two battery-powered toothbrushes.

PURPOSE: To compare the plaque removal efficacy of a positive control power toothbrush (Colgate Actibrush) to an experimental power toothbrush (Crest SpinBrush) following a single use. MATERIALS AND METHODS: This study was a randomized, controlled, examiner-blind, 4-period crossover design which examined plaque removal with the two toothbrushes following a single use in 39 completed subjects. Plaque was scored before and after brushing using the Turesky Modification of the Quigley-Hein Index. RESULTS: Baseline plaque scores averaged 2.18 and 2.16 for the experimental toothbrush and control toothbrush treatment groups, respectively. With respect to all surfaces examined, the experimental toothbrush delivered an adjusted (via analysis of covariance) mean difference between baseline and post-brushing plaque scores of 0.66 while the control toothbrush delivered an adjusted mean difference of 0.43. This represents an increase of 55% plaque removal relative to the control power toothbrush. The difference between brushes was statistically significant (P < 0.001). With respect to buccal and lingual surfaces, the experimental toothbrush delivered very consistent results relative to the control toothbrush. The differences between brushes were also statistically significant (P < 0.001).

Adolescent↗
PubMed2002

Plaque removal efficacy of a battery-operated power toothbrush compared to two control manual toothbrushes in single use studies.

PURPOSE: Recently, a power toothbrush (Crest SpinBrush) has been reported to remove plaque more effectively than a manual toothbrush (Colgate Navigator). The objective of these studies was to compare the plaque removal efficacy of two control manual toothbrushes (Colgate Wave and Colgate Plus) to an experimental power toothbrush (Crest SpinBrush). The Colgate Plus has an ordinary flat bristle trim design, while the Colgate Wave has an advanced design multilevel bristle trim for greater interproximal penetration. MATERIALS AND METHODS: Each of these two studies were randomized, controlled, examiner-blind, 4-period crossover designs which examined plaque removal with the experimental toothbrush relative to a control manual toothbrush following a single use in 37 and 35 subjects, respectively. Plaque was scored before and after brushing using the Turesky Modification of the Quigley-Hein Index. RESULTS: In the first study, average baseline plaque scores were 2.88 and 2.89 for the experimental toothbrush and advanced designed manual control toothbrush (Colgate Wave) treatment groups, respectively. With respect to all surfaces examined, the experimental toothbrush delivered an adjusted (via analysis of covariance) mean difference between baseline and post-brushing plaque scores of 0.70 while the control toothbrush delivered an adjusted mean difference of 0.59. The difference between the brushes was statistically significant (P < 0.001). The experimental toothbrush removed, on average, 19.9% more plaque than the control toothbrush. In the second study, baseline plaque scores averaged 3.07 and 3.04 for the experimental toothbrush and ordinary flat trim manual control toothbrush (Colgate Plus) treatment groups, respectively. With respect to all surfaces examined, the experimental toothbrush delivered an adjusted (via analysis of covariance) mean difference between baseline and post-brushing plaque scores of 0.87 while the control toothbrush delivered an adjusted mean difference of 0.62. The difference between brushes was statistically significant (P < 0.001). The experimental toothbrush removed, on average, 40.0% more plaque than the control toothbrush.

Adolescent↗
PubMed2002

Dental plaque removal efficacy of a battery-powered toothbrush vs. a control Japanese manual toothbrush.

PURPOSE: Recently, a new powered toothbrush has been marketed with a design that fundamentally differs from other marketed powered toothbrushes, in that it incorporates a round oscillating head, in conjunction with fixed bristles. The objective of this study was to compare the plaque removal efficacy of a control manual toothbrush (Lion Dentor Systema) to this experimental powered toothbrush (Crest SpinBrush) following a single use. MATERIALS AND METHODS: This study was a randomized, controlled, examiner-blind, 4-period crossover design which examined plaque removal with the two toothbrushes following a single use in 36 subjects. Plaque was scored before and after brushing using the Turesky Modification of the Quigley-Hein Index. RESULTS: Baseline plaque scores were 2.90 for the experimental toothbrush and 2.95 for the control toothbrush treatment groups. With respect to all surfaces examined, the experimental toothbrush delivered an adjusted (via analysis of covariance) mean difference between baseline and post-brushing plaque scores of 0.70 while the control toothbrush delivered an adjusted mean difference of 0.54. The difference between treatment groups was statistically significant (P < 0.001). The experimental toothbrush removed, on average, 29.6% more plaque than the control toothbrush. With respect to buccal surfaces, the experimental toothbrush delivered an adjusted mean difference between baseline and post-brushing plaque scores of 1.09 while the control toothbrush delivered an adjusted mean difference of 0.90. This difference between treatment groups was also statistically significant (P = 0.001) and represents, on average, 21.1% more plaque removal with the experimental toothbrush. Results on lingual surfaces also demonstrated statistically significantly (P< 0.001) greater plaque removal for the experimental toothbrush with an average of 83.3% more plaque removal.

Adult↗
PubMed2002

Laboratory evaluations of two battery-powered toothbrushes and a manual toothbrush for efficacy and safety.

Two laboratory testing procedures, predictive of clinical efficacy and safety, have been used to evaluate two battery-powered toothbrushes (a new prototype, Crest SpinBrush Pro and a commercially available product, Crest SpinBrush) and a standard manual toothbrush (Oral-B Indicator). Interproximal access efficacy (IAE) and depth of deposit removal (DDR) have been evaluated in laboratory methods using pressure-sensitive paper placed around simulated anterior and posterior teeth at a brushing pressure of 250 g with horizontal or vertical brushing motions. Twenty-four tests on each toothbrush design were conducted, and results were statistically analyzed using ANOVA and the post hoc Tukey test. Both of the battery-powered toothbrushes had a significantly (p < 0.001) higher mean overall IAE value compared to the Oral-B Indicator product. The Crest SpinBrush Pro was significantly statistically higher (p < 0.05) compared to the Crest SpinBrush for mean overall IAE (access to interproximal spaces). On overall DDR, both of the powered toothbrushes had a significantly (p < 0.05-0.001) lower mean overall value compared to the Oral-B Indicator toothbrush (higher mean indicates higher irritation potential). Based on these results, both the new prototype Crest SpinBrush Pro and the commercially available Crest SpinBrush are predicted to be more effective clinically for plaque removal, and at least as safe on hard and soft intraoral tissues as the standard manual toothbrush (Oral-B Indicator) tested. In addition, the results support that the new prototype Crest SpinBrush Pro is more effective than the Crest SpinBrush with respect to IAE and predicted plaque removal.

Analysis of Variance↗