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Abdul-Ghani Kibbi

Publications and source records attributed to Abdul-Ghani Kibbi.

5 recordsLinked to original sources
PubMed2005

HLA allele associations and V-beta T-lymphocyte expansions in patients with psoriasis, harboring toxin-producing Staphylococcus aureus.

HLA alleles have been associated with psoriasis. Toxin-producing strains of Staphylococcus aureus behave as superantigens, and if present in patients, might play a role in the exacerbation of psoriatic lesions by activating certain V-beta (V beta) T-lymphocyte subsets. Allele frequencies in 22 patients and 22 controls (alleles determined by DNA/SSP typing) were used to calculate a relative risk of $4.7$ ($P < .05$) for HLA-Cw6. S aureus was isolated from the throat of 11 patients. Enterotoxins A and C were detected by agglutination in the culture filtrate of one isolate. The enterotoxin A and/or C genes were detected by PCR in 9 isolates, and transcripts were detected by RT-PCR in 7 of them. None of the isolates from controls harbored enterotoxin genes. V beta expansions were detected by RT-PCR in all 22 patients. Low or no V beta expansions were obtained in controls. The association of HLA-Cw6 with psoriasis in Lebanese concurs with that reported for other ethnic groups. Toxin-producing isolates that colonize patients might play a role in the exacerbation of psoriatic lesions.

Journal Article↗
PubMedDate not supplied

Cutaneous gonococcal infections.

Cutaneous gonococcal infections are frequent in the United States and other industrialized countries. This bacterial infection commonly affects the genitourinary tract and may rarely involve the skin. Cutaneous lesions are either primary or secondary to disseminate disease. The diagnosis of gonorrhea is based on clinical ground and is best confirmed by the isolation of the organism. Preventive measures including periodic screening of high-risk individuals and behavioral counseling are effective in controlling the disease.

Diagnosis, Differential↗
PubMedDate not supplied

Less well-defined dermatoses of pregnancy.

Over the past several decades, many specific and nonspecific dermatoses of pregnancy have been described. The lack of a well-defined clinical and histological features as well as reproducibility in some of these entities has led to confusing reports in the literature. In this review article, an account of these nonspecific dermatoses of pregnancy will be presented in an attempt to shed light on their nosology and to better categorize them in view of the recent literature findings.

Female↗