Biomedical subjects

Abla Albsoul-Younes

Publications and source records attributed to Abla Albsoul-Younes.

5 recordsLinked to original sources

PubMed2006

Pharmacy education in Jordan, Saudi Arabia, and Kuwait.

The practice of pharmacy, as well as pharmacy education, varies significantly throughout the world. In Jordan, Kuwait, and Saudi Arabia, the profession of pharmacy appears to be on the ascendance. This is demonstrated by an increase in the number of pharmacy schools and the number of pharmacy graduates from pharmacy programs. One of the reasons pharmacy is on the ascendance in these countries is government commitment to fund and support competitive, well-run pharmacy programs. In this report we describe pharmacy education in 3 Middle East countries: Jordan, Kuwait, and Saudi Arabia. All 3 countries offer bachelor of pharmacy (BPharm) degrees. In addition, 2 universities in Jordan and 1 in Saudi Arabia offer PharmD degree programs. The teaching methods in all 3 countries combine traditional didactic lecturing and problem-based learning. Faculties of pharmacy in all 3 countries are well staffed and offer competitive remuneration. All 3 countries have a policy of providing scholarships to local students for postgraduate training abroad. The majority of students in Jordan and Kuwait are female, while the ratio of male to female students in Saudi Arabia is even. Students' attitudes towards learning are generally positive in all 3 countries. In Saudi Arabia and Kuwait, most pharmacy graduates work in the public sector, while in Jordan, the majority work in the private sector.

Education, Pharmacy↗

PubMed2006

Topical phenytoin ointment increases autograft acceptance in rats.

OBJECTIVE: To examine the effectiveness of topical phenytoin in preserving the skin viability and increasing acceptance rate of autograft. METHODS: We conducted this study in the Central Laboratory Animal House of Jordan University of Science and Technology, Irbid, Jordan during the period from September 2004 to June 2005. Forty-two rats were divided into 2 equal groups; full thickness dorsal skin wound (4 cm2) was created in the rats. Twenty-one rats were treated with phenytoin (10% w/w ointment), the other 21 (control) were treated with standard dressing and Vaseline. An autograft was performed one week after treatment. Rats were examined for the presence of healthy granulation tissue, reduction in wound surface dimensions, and time for complete graft attachment. RESULTS: Phenytoin ointment had significantly increased wound bed viability and the rate of graft acceptance (p-value <0.0001). Twenty rats had successful grafting (10% phenytoin); while only 3 rats out of the 21 control had successful grafts. The mean time to complete graft attachment and hair growth in the grafted skin was 6.6 +/- 0.5 days. The mean wound contraction measurements (taken just before grafting) were as follow: control group 59.2 +/- 11.6%, and phenytoin group 55.7 +/- 9.2, difference in skin contractility was not statistically significant. Skin viability was evident by increased vascularity and granular tissue formation at the edges of the wound. CONCLUSION: Phenytoin appears to be an effective method for enhancing the take of the full-thickness skin graft. Further clinical use and evaluation of topical phenytoin ointment in skin grafting are merited.

Animals↗

PubMed2005

Pharmacy in Jordan.

Explore the source record for details and available documents.

Biomedical Research↗

PubMed2005

Variable omeprazole kinetics in healthy Jordanian adults.

OBJECTIVES: The objective of this study was to examine the pharmacokinetics of orally administered omeprazole in healthy adult Jordanian men. METHOD: Plasma concentrations of omeprazole were measured over a 12 h period after administration of a single oral dose of 40 mg omeprazole (Losec), AstraZeneca, UK). Subjects were healthy adult Jordanian men age 18-38 (24 +/- 4, mean +/- SD). The pharmacokinetic parameters were derived from the plasma concentration-time profiles for AUC(0-t), AUC(0-inf), C(max), t(max), t(1/2e) and K(e). RESULTS: The pharmacokinetic of omeprazole were scattered over a wide range. The median AUC(0-inf) was 784.86 +/- 1182.88 (ng.h/ml), and the median C(max) was 521 +/- 354 (ng/ml) (median +/- SD). In general, most subjects showed normal distribution (approximately 90%). Some subjects (10%) did show very high AUC and C(max) compared with the reported AUC and C(max) levels. These subjects had higher half-lives and lower rates of elimination. CONCLUSION: Significant difference in the pharmacokinetics of omeprazole after a single dose administration was noted. Approximately 10% of the study group showed very high omeprazole plasma levels and AUCs. Differences in the pharmacokinetics might be due to differences in the genetic make-up of subjects.

Administration, Oral↗

PubMed2005

Clustering of coronary artery disease risk factors in Jordanian hypertensive patients.

OBJECTIVE: To assess the coronary artery disease risk factors in hypertensive Jordanian patients in various hospitals in Jordan. METHODS: Two hundred and seven patients were assessed by physicians in various hospitals in Jordan including King Hussein Medical Center , Prince Rashid Medical Hospital and King Abdullah University Hospital Primary Health Care Internal Medicine Clinic from March 2003 to October 2003. Clinical assessment included blood pressure (BP), anthropometric data, metabolic and chemical profile were collected. RESULTS: The average age of sample was 58.9 + 11.28 years old. The mean body mass index was 29.4 + 6.4 kg/m2, 77 patients (37.2%) were overweight and 83 patients (40.1%) were obese. Smoking habit was prevalent in 78 patients (37.7%). Analysis of data showed that female had a higher systolic BP than male, while male had a higher diastolic BP than female. The mean serum cholesterol level was 205.7 + 65.7 mg/dl, while the mean fasting blood glucose was 150.1 + 63.9 mg/dl. The sample was staged according to the Joint National Committee on Prevention, Detection, Evaluation and Treatment of High BP classification, 87 patients (42%) showed optimal and normal BP (<130/85 mm Hg), 40 patients (19.3%) showed high normal BP (130-139/85-89 mm Hg), 47 patients (22.7%) with stage 1 hypertension (140-159/90-99 mm Hg), 15 patients (7.2%) with stage 2 hypertension (160-179/100-109 mm Hg) and 18 patients (8.7%) with stage 3 hypertension (>180/110 mm Hg). The high prevalence of risk factors in hypertensive patients is alarming, particularly the high prevalence of poor control of BP, smoking in men, hypercholesterolemia and obesity in women. CONCLUSION: The BP control is inadequate in large percentage of this sample and a number of risk factors cluster in both adequately and inadequately controlled hypertensive patients.

Aged↗