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Biomedical subjects

Abraham Rijbroek

Publications and source records attributed to Abraham Rijbroek.

2 recordsLinked to original sources

Endovascular repair of a type B aortic dissection with transposition of a coexistent aberrant subclavian (lusorian) artery.

PURPOSE: To report the endovascular treatment of a relatively uncommon entity: an aortic type B dissection combined with an aberrant subclavian artery (SA). CASE REPORT: A 59-year-old patient was admitted with chest pain and interscapular back pain. A transesophageal ultrasound and magnetic resonance angiography revealed a type B aortic dissection originating at the level of an aberrant SA orifice. After failure of medical therapy, the dissection was treated by transluminal implantation of an Excluder stent-graft covering the entry site of the dissection at the aberrant SA orifice. Prior to the endovascular procedure, a transposition of the aberrant SA to the right carotid artery was performed through a supraclavicular approach. The patient remains asymptomatic at 19 months after the endovascular repair. CONCLUSIONS: Endovascular repair of a type B aortic dissection in the presence of a lusorian artery appears to be a feasible, safe, and less invasive alternative to conventional surgery. The need for concurrent transposition of the SA remains to be determined.

Aortic Dissection↗

Evaluation of basis function and linear least squares methods for generating parametric blood flow images using 15O-water and Positron Emission Tomography.

PURPOSE: Parametric analysis of (15)O-water positron emission tomography (PET) studies allows determination of blood flow (BF), perfusable tissue fraction (PTF), and volume of distribution (V (d)) with high spatial resolution. In this paper the performance of basis function and linear least squares methods for generating parametric flow data were evaluated. PROCEDURES: Monte Carlo simulations were performed using typical perfusion values for brain, tumor, and heart. Clinical evaluation was performed using seven cerebral and 10 myocardial (15)O-water PET studies. Basis function (BFM), linear least squares (LLS), and generalized linear least squares (GLLS) methods were used to calculate BF, PTF, or V(d). RESULTS: Monte Carlo simulations and human studies showed that, for low BF values (<1 ml/min(-1)ml(-1), BF, PTF, and V(d) were calculated with accuracies better than 5% for all methods tested. For high BF (>2 ml/min(-1)ml(-1)), use of BFM provided more accurate V(d) compared with (G)LLS. CONCLUSIONS: In general, BFM provided the most accurate estimates of BF, PTF, and V(d).

Brain↗