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Biomedical subjects

Acke Ohlin

Publications and source records attributed to Acke Ohlin.

8 recordsLinked to original sources

Vertebral fractures in late adolescence: a 27 to 47-year follow-up.

The long-term outcome of thoracic and lumbar fractures in late adolescence is sparsely described and it is unclear whether a fractured vertebral body in these years, as in young children, can be resituated in height. The purpose of this study was to in late adolescence determine the incidence, the long-term outcome and the modelling capacity in fractures of the thoracic and lumbar region. The incidence of vertebral fractures 1950-1971 in individuals aged 16-18 years was through the radiological archives evaluated in a city cohort of 228,878 citizens, of whom 13,893 were aged 16-18. A follow-up, 27-47 years after the injury, including subjective, objective and radiological evaluation was conducted in 18 boys and 5 girls. Twenty-nine boys and 11 girls were registered with a thoracic or lumbar vertebral fracture during the study period conferring an annual incidence of 0.14 per thousand. Of the 23 individuals that attended the follow-up, 14 had one-column compression fractures, one a Denis type A, six a Denis type B, one a Denis type D and one a Chance fracture. At injury, one had a partial paresis in one leg and one developed a transient paraparesis during the first week. All were treated non-operatively. At follow-up, 18 individuals had no complaints while 5 had occasional back pain, 20 were classified as Frankel E and 3 as Frankel D. The radiographic ratio of anterior height to posterior height of the fractured vertebral body was unchanged during the study period. Thoracic and lumbar vertebral fractures in late adolescence with no or minor neurological deficits have a predominantly favourable long-term outcome, even if no modelling capacity of the fractured vertebral body remains in late adolescence.

Adolescent↗

Vertebroplasty and kyphoplasty: New treatment strategies for fractures in the osteoporotic spine.

During the last decade, two new treatment modalities for osteoporotic vertebral fractures have gained more interest: percutaneous vertebroplasty and kyphoplasty. The techniques and the short-term clinical results and complications have been presented but there is no scientific evidence-based information regarding the efficacy of the procedures, such as randomized controlled trials (RCT). Instead, we have to rely on prospective and retrospective uncontrolled short-term observational studies and case-control studies. These studies have shown consistently that the short-term results after the procedures are favorable as regards both pain relief and functional status. It is currently unknown, however, whether a vertebroplasty or a kyphoplasty gives a better outcome than nonoperative treatment, and whether the long-term results are as favorable as the short-term results.

Humans↗

Grisel syndrome after velopharyngoplasty.

We describe two patients with Grisel syndrome (atlantoaxial dislocation) after velopharyngoplasty. One required open fixation, while the other was treated with closed reduction and skull traction. Both patients recovered well after long-term follow-up. Early detection and appropiate treatment improve the prognosis.

Atlanto-Axial Joint↗

Vertebroplasty and kyphoplasty in the fractured osteoporotic spine.

Percutaneous vertebroplasty and kyphoplasty have during the last decade gained an increasing popularity in the treatment of osteoporotic fractures of the spine. The techniques, clinical results and complications are described. There is however a disturbing lack of scientific evidence regarding the efficacy of the procedures, no controlled studies are published. An ongoing prospective randomised study is presented.

Fractures, Spontaneous↗

A modeling capacity of vertebral fractures exists during growth: an up-to-47-year follow-up.

STUDY DESIGN: The study is an observational cohort study. OBJECTIVES: To determine the incidence and the long-term outcome of thoracic or lumbar vertebral fractures in children. SUMMARY OF BACKGROUND DATA: The incidence of vertebral fractures in children is described as rare and the outcome as favorable. However, no studies evaluate the clinical and radiographic long-term outcome and if a fractured vertebra could be rebuilt during growth. METHOD: The incidence of vertebral fractures in children was evaluated through the radiographic archives. Twelve boys and 12 girls, aged 7-16 when sustaining the fracture, 21 one-column compression fractures and 3 burst fractures Denis type B, all without neurologic deficits, attended the follow-up. Primary treatment consisted of immediate mobilization without brace. Clinical and radiographic examinations were performed 27-47 years after the injury. RESULTS: The annual incidence of thoracic and lumbar vertebral body fractures in individuals below age 16 was 0.07%. Twenty-one individuals had, at follow-up, no subjective complaints, 3 had occasional back pain (Oswestry Scores 8, 22, and 26), 23 were classified as Frankel E, and 1 as Frankel D. The radiographic ratio anterior height/posterior height of the fractured vertebral body increased from 0.75 after injury to 0.87 at follow-up (P < 0.001). The posttraumatic kyphosis in the fractured region decreased in 8 individuals (33%), all aged 13 or less at fracture. No increased disc degeneration was observed. CONCLUSION: Thoracolumbar vertebral fractures without neurologic deficits, sustained during growth, have a favorable long-term outcome. A modeling capacity, reducing the fracture deformity, exists at least in the youngest patients.

Adolescent↗

Posterior transpedicular stabilisation of the infected spine.

BACKGROUND: Six men and seven women, aged 62 years, bedridden due to back pain from a septic spondylitis in the thoracolumbar region and not responding to conservative treatment, were operated on with transpedicular stabilisation of the affected segments to enhance mobilisation. All patients experienced immediately reduced back pain, allowing them to leave their bed and start mobilisation during the first postoperative day. At follow-up after a mean of 29 months (range 13-60 months) only one was using analgesics. RESULTS: Nine of the 11 patients with pathological neurology at surgery had improved, none had deteriorated, and all were ambulatory without bladder or bowel disturbances. Seven had achieved a solid interbody fusion, with a continued radiographic decrease in the spondylitic change in the rest, indicating that a progressive interbody fusion was in progress. Three individuals had increased kyphosis, a mean of 11 deg compared with the postoperative radiographs.

Aged↗

[Treatment of osteoporotic vertebral compression. Explosive interest for vertebroplasty and kyphoplasty].

During the last 15 years, two new treatment strategies have gained worldwide attention in the treatment of osteoporotic vertebral fractures. The exponential increase in the use of percutaneous vertebro- or kyphoplasty has up to now not been supported by scientific sound evidence-based data. There exist no prospective randomised controlled trials (RCT) that support the efficacy of the treatments, not even adequate controlled studies. Instead we have to rely on prospective and retrospective uncontrolled short-term observational studies and case-control studies. These studies consistently indicate that the short-term results after the procedures in the treatment of osteoporotic vertebral fractures are favourable, regarding both pain relief and functional status. However, if a vertebro- or a kyphoplasty produces a better outcome than conservative treatment, and if the long-term results are as favourable as the short-term results in the treatment of osteoporotic vertebral fractures, is currently unknown.

Aged↗